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Anti-cancer quinazoline derivatives

  • US 5,236,927 A
  • Filed: 12/12/1990
  • Issued: 08/17/1993
  • Est. Priority Date: 05/31/1985
  • Status: Expired due to Fees
First Claim
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1. A compound of formula I:

  • ##STR12## wherein R is1) hydrogen;

    or2) an alkyl, alkenyl or alkynyl group of up to 6 carbon atoms;

    n is O;

    1 or 2;

    Z represents --CH═

    CH-- [or --O--] or --S--;

    each X independently represents halogeno, C1 -C4 alkyl, C1 -C4 alkoxy, nitro or trifluoromethyl; and

    Y represents a group of formula;

    ##STR13## or a pharmaceutically acceptable salt or ester thereof.

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