Disposable powder medicament inhalation device with peel-off cover

• US 5,239,991 A
• Filed: 05/19/1992
• Issued: 08/31/1993
• Est. Priority Date: 06/21/1989
• Status: Expired due to Term

• Current Assignee: Fisons PLC (Sanofi )
• Original Assignee: Fisons PLC (Sanofi )
• Inventors: Clark, Andrew R., Chawla, Brindra P. S.
• Primary Examiner(s): Burr, Edgar S.
• Assistant Examiner(s): Asher, Kimberly L.
• Application Number:
  US07/887,108
• Time in Patent Office: 469 Days
• Field of Search: 128/203.12, 128/203.13, 128/203.15, 128/204.11, 128/203.23, 128/203.14, 206/363, 206/530, 206/532, 206/534.1, 206/534.2, 206/538, 206/539, 220/23.4
• US Class Current: 128/203.15
• CPC Class Codes: A61M 15/00 Inhalators drug delivery in endotracheal tubes A61M16/04
• CPC Class Codes: A61M 2202/064 Powder

Abstract

A disposable device for the administration of powdered inhalation medicament is provided which comprises a rigid medicament reservoir (4) holding a unit dose of medicament (10) and having air inlet means (5,7) and medicament outlet means (8); and closure means (3) which are removable in use; wherein the medicament (10) held in the reservoir (4) is in loose powder form.

Claims

1. A disposable device for the administration of powdered inhalation medicament to a patient, said device comprising:

(a) a flat base member;

(b) a raised upper portion attached to the base member defining a rigid medicament reservoir holding a unit dose of medicament in loose powder form, said reservoir acting as a mouthpiece;

(c) an arm extending from the medicament reservoir defining an air passageway connecting an air inlet provided at one end of the arm with the medicament reservoir at the other end;

(d) medicament outlet means comprising a group of openings provided in a wall of the medicament reservoir through which the medicament is inhaled; and

(e) closure means comprising a cover sheet peelably attached to an outer surface of the device which seals both the openings of the air inlet means and the medicament outlet means;

such that in use upon removal of the closure means and inhalation through the mouthpiece by a patient, air is drawn into the air inlet and along the air passageway into the reservoir causing medicament to be entrained in the air stream and inhaled by the patient.

2. A disposable device according to claim 1, wherein the air inlet means comprise one or more openings having a total inlet cross sectional area and the medicament outlet means comprise one or more openings having a total outlet cross sectional area;

further characterized in that the ratio of the total outlet cross sectional area to the total inlet cross sectional area is in the range of from 1;

1 to 1;

10.

3. A disposable device according to claim 1, further characterized in that the device is provided with a sufficient number of reservoirs to provide one day'"'"'s supply of medicament to a patient.

4. A disposable device according to claim 1, further characterized in that the medicament held by the reservoir is selected from the group consisting of sodium cromoglycate and nedocromil sodium.

5. A disposable device according to claim 1, further characterized in that an inner surface of the reservoir is provided with a baffle so as to produce air turbulence in use.