Antipsychotic chroman derivatives of benzodioxanmethylamine
First Claim
Patent Images
1. A compound of the formula:
- ##STR11## wherein R1 and R2 are, independently, hydrogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, aralkoxy of 7 to 12 carbon atoms, alkanoyloxy of 2 to 6 carbon atoms, hydroxy, halo, amino, mono- or dialkylamino in which each alkyl group has 1 to 6 carbon atoms, alkanamido of 2 to 6 carbon atoms, or sulfonamido, or R1 and R2 together are methylenedioxy, ethylenedioxy, or propylenedioxy;
R3 is hydrogen or alkyl of 1 to 6 carbon atoms;
n is an integer 2,3 or 4;
X is --C(═
O)-- or --(CH2)m --, in which m is the integer 0 or 1;
Y is methylene, ethylene or ethylidene;
or a pharmaceutically acceptable salt thereof.
2 Assignments
0 Petitions
Accused Products
Abstract
A compound of the formula: ##STR1## wherein R1 and R2 are, independently, hydrogen, alkyl, alkoxy, aralkoxy, alkanoyloxy, hydroxy, halo, amino, mono- or dialkylamino, alkanamido or sulfonamido, or R1 and R2 together are methylenedioxy, ethylenedioxy, or propylenedioxy; R3 is hydrogen or alkyl; n is one of the integers 2,3 or 4; X is --C(═O)-- or --(CH2)m --, in which m is the integer 0 or 1; Y is methylene, ethylene or ethenylene, or a pharmaceutically acceptable salt thereof, are antipsychotic agents.
18 Citations
12 Claims
-
1. A compound of the formula:
- ##STR11## wherein R1 and R2 are, independently, hydrogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, aralkoxy of 7 to 12 carbon atoms, alkanoyloxy of 2 to 6 carbon atoms, hydroxy, halo, amino, mono- or dialkylamino in which each alkyl group has 1 to 6 carbon atoms, alkanamido of 2 to 6 carbon atoms, or sulfonamido, or R1 and R2 together are methylenedioxy, ethylenedioxy, or propylenedioxy;
R3 is hydrogen or alkyl of 1 to 6 carbon atoms; n is an integer 2,3 or 4; X is --C(═
O)-- or --(CH2)m --, in which m is the integer 0 or 1;Y is methylene, ethylene or ethylidene;
or a pharmaceutically acceptable salt thereof. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
- ##STR11## wherein R1 and R2 are, independently, hydrogen, alkyl of 1-6 carbon atoms, alkoxy of 1-6 carbon atoms, aralkoxy of 7 to 12 carbon atoms, alkanoyloxy of 2 to 6 carbon atoms, hydroxy, halo, amino, mono- or dialkylamino in which each alkyl group has 1 to 6 carbon atoms, alkanamido of 2 to 6 carbon atoms, or sulfonamido, or R1 and R2 together are methylenedioxy, ethylenedioxy, or propylenedioxy;
Specification