Multi-isotope imaging using energy-weighted acquisition for, e.g., myocardial perfusion studies

• US 5,249,124 A
• Filed: 04/16/1991
• Issued: 09/28/1993
• Est. Priority Date: 04/16/1991
• Status: Expired due to Fees

• Current Assignee: Siemens Gammasonics Incorporated
• Original Assignee: Siemens Gammasonics Incorporated
• Inventors: DeVito, Raymond P.
• Primary Examiner(s): NOT, DEFINED
• Assistant Examiner(s): Tran, Khai
• Application Number:
  US07/685,940
• Time in Patent Office: 896 Days
• Field of Search: 364/413.24, 364/414, 364/581, 364/724.12, 364/485, 364/413.16, 250/363.02, 250/363.04, 250/363.07, 250/367, 250/369, 378/901, 378/14, 378/15
• US Class Current: 250/363.04
• CPC Class Codes: A61B 6/037 Emission tomography
• CPC Class Codes: A61B 6/4258 for detecting non x-ray radiation, e.g. gamma radiation A61B6/037 takes precedence
• CPC Class Codes: G01T 1/1642 using a scintillation crystal and position sensing photodetector arrays, e.g. ANGER cameras

Abstract

A multi-isotope study is carried out using a plurality of imaging agents which are imaged simultaneously. The information obtained is weighted using as many energy weighting functions as there are isotopes. The weighting reduces "crosstalk" between each of the single-isotope images which are produced as a result of the study. This produces improved results in, for example, dual-isotope (Tc-99m and Tl-201) myocardial perfusion studies.

Claims

1. A method of conducting a multi-isotope study using a gamma camera and a plurality of isotopes, comprising the step of weighting information acquired by the gamma camera with as many weighting functions as there are isotopes.

2. The method of claim 1, further comprising the step of producing as many planar images as there are isotopes.

3. The method of claim 1, further comprising the step of producing as many tomographic images as there are isotopes.

4. A method of conducting a multi-isotope study using a gamma camera and a plurality of isotopes, said gamma camera producing information in an event-by-event format, the method comprising the step of weighting the information in real time using as many energy-based weighting functions as there are isotopes and producing as many images as there are isotopes.

5. A method of conducting a multi-isotope study using a gamma camera and a plurality of isotopes, said gamma camera producing information, in an event-by-event format, the method comprising the step of weighting the information using as many energy-based weighting functions as there are isotopes and producing as many images as there are isotopes, said weighting step being carried out in a post-processing mode after all the information has been accumulated.

6. A method of conducting a multi-isotope study using a gamma camera and a plurality of isotopes, said gamma camera producing information in a frame-by-frame format, the method comprising the step of weighting the information using as many energy-based weighting convolution functions as there are isotopes and producing as many images as there are isotopes, said weighting step being carried out in a post-processing mode after all the information has been accumulated.

7. A method of conducting a multi-isotope study using a gamma camera and a plurality of isotopes, said gamma camera producing information in a region-by-region format, the method comprising the step of spectrally deconvolving the information using as many energy spectrum-based deconvolution functions as there are isotopes and producing as many images as there are isotopes, said deconvolving step being carried out in a post-processing mode after all the information has been accumulated.