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Spatially-addressable immobilization of anti-ligands on surfaces

  • US 5,252,743 A
  • Filed: 11/13/1990
  • Issued: 10/12/1993
  • Est. Priority Date: 11/13/1989
  • Status: Expired due to Term
First Claim
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1. A caged binding member compound having the formula:

  • ##STR30## wherein X and Z are selected from the group consisting of hydrogen and oxycarbonyls of lower alkyl, aryl, and benzyl groups, provided that when X is hydrogen, Z is not hydrogen or methyloxycarbonyl, and provided that when Z is hydrogen, X is not hydrogen or methyloxycarbonyl;

    R is selected from the group consisting of hydrogen, lower alkyl, aryl, lower alkyl formate, aryl formate, formamide, N-alkylformamide, N-succinimidyl, hydroxyl, alkoxyl, thiol, thioether, disulfide, hydrazide and amine groups, provided that when X or Z is methyloxycarbonyl, R is not methyl formate;

    U is O, S, or NH;

    Y is selected from the group consisting of sulfur oxygen, methylene, carbonyl, sulfinyl and sulfonyl groups or Y represents two hydrogen atoms attached to the respective carbons;

    n=1-7; and

    acid addition salts of the compound.

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