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3-hydroxy-pyridin-4-ones useful for treating parasitic infections

  • US 5,256,676 A
  • Filed: 07/24/1992
  • Issued: 10/26/1993
  • Est. Priority Date: 04/27/1992
  • Status: Expired due to Fees
First Claim
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1. A method for the treatment of a patient having a condition caused by an iron dependent parasite which comprises administering to that patient a therapeutically effective amount of a 3-hydroxypyridin-4-one of formula (I) ##STR6## in which R1 is a C3 or C4 hydroxyalkyl group in which the hydroxy group is terminally substituted on the alkyl group, R2 is methyl or ethyl and R3 and R4 are each separately hydrogen, methyl or ethyl but with the proviso that the total number of carbon atoms in R1 to R4 is no more than six, the compound optionally being in the form of a physiologically acceptable salt and/or pro-drug thereof.

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