Wound closure means and method using flowable adhesive

• US 5,259,835 A
• Filed: 08/29/1991
• Issued: 11/09/1993
• Est. Priority Date: 08/29/1991
• Status: Expired due to Term

• Current Assignee: Ethicon Incorporated (Johnson & Johnson)
• Original Assignee: TRI-Point Medical L.P.
• Inventors: Clark, Jeffrey G., Mulhauser, Paul J., Spranger, Douglas M., Lacotta, Paul R.
• Primary Examiner(s): Isabella, David
• Assistant Examiner(s): PREBILIC, PAUL B
• Application Number:
  US07/752,019
• Time in Patent Office: 803 Days
• Field of Search: 602/48, 602/54, 602/55, 602/58, 602/59, 606/213, 606/214, 606/215, 606/216, 604/289, 604/310
• US Class Current: 602/48
• CPC Class Codes: A61B 17/08 Wound clamps or clips, i.e. not or only partly penetrating the tissue suture bridges A61B17/0466; Devices for bringing together the edges of a wound
• CPC Class Codes: A61F 13/0226 characterised by the support layer
• CPC Class Codes: A61F 13/0246 characterised by the skin-adhering layer
• CPC Class Codes: A61F 2013/00459 with cyano-acrylic adhesive adhesives for mucosae A61F2013/00714 or for use on wounds A61F2013/00719
• CPC Class Codes: A61F 2013/00608 with reinforcing layers
• CPC Class Codes: A61F 2013/00672 cyano-acrylic
• CPC Class Codes: A61F 2013/00731 with absorbing pads
• CPC Class Codes: A61F 2013/00804 different adhesion of different adhesive layers plasters with a double adhesive layer A61F2013/00421; with cyano-acrylic adhesive A61F2013/00459; with adhesive connecting means A61F2013/00561; adhesives for plasters A61F2013/00655; with absorbent adhesives A61F2013/00757; with permeable adhesive layers A61F2013/00761; changing the adhesion force with strain value A61F2013/00838
• CPC Class Codes: A61F 2013/00817 handles or handling tabs
• CPC Class Codes: A61F 2013/00859 with macroscopic openings
• CPC Class Codes: A61F 2013/00897 package for individual plaster

Abstract

A wound closure device employs a porous bonding member which receives a flowable adhesive capable of providing long term wound support. The bonding member is positioned by a carrier member that is used to achieve initial apposition of the wound and which may later be removed. An intermediate barrier may be provided between the bonding pad and the wound site. Alternatively, a rigid applicator may be utilized for positioning the bonding pad at the wound site. The closure device can include a supply of flowable adhesive for adhering the bonding member to the skin of the patient. Suitable flowable adhesives are cyanoacrylates. A form of packaging supports the wound closure member for preapplication of the adhesive and can serve as a part of a sterile barrier package.

Claims

1. A wound closure system comprising:

a porous bonding member;

means for affixing the porous bonding member in a wound apposing position on the skin of a patient; and

a source of flowable adhesive and a means for delivering the flowable adhesive to the bonding member, whereby, upon application of the adhesive to the bonding member, the adhesive flows through the bonding member and adheres the porous member to the skin of the patient.

2. The wound closure system of claim 1, wherein the adhesive source of flowable comprises a container having a cyanoacrylate adhesive contained therein.

3. A wound closure system as in claim 1, further comprising a sterility barrier package, said bonding member and said positioning means being in a sterile condition within said barrier package.

4. A wound closure system as in claim 3, wherein the adhesive delivery means is disposed within said barrier package.

5. A wound closure system comprising:

a carrier member;

means on the carrier member for holding edges of a wound of a patient in apposed condition;

a porous wound apposing member for receiving a flowable adhesive;

means for mounting the wound apposing member on the carrier member; and

a source of flowable adhesive and a means for delivering the flowable adhesive to the porous wound apposing member.

6. A wound closure system as in claim 5, wherein the carrier member is formed of a flexible sheet material.

7. A wound closure system as in claim 6, further comprising an aperture in the carrier member, said wound apposing member being located on one side of the carrier member and overlying said aperture.

8. A wound closure system as in claim 6, wherein the means on the carrier member for holding the wound in apposed condition comprises a contact adhesive.

9. A wound closure system as in claim 6, wherein the means for mounting the porous wound apposing member on the carrier member comprises means for readily releasably securing the porous wound apposing member on the carrier member.

10. A wound closure system as in claim 5, wherein the porous wound apposing member is a body formed of fibrous material.

11. A wound closure system as in claim 5, further comprising a liquid impervious membrane, said membrane being positioned to cover at least a portion of a patient contact surface of the wound apposing member.

55. A wound closure system as in claim 5, wherein the means on the carrier member for holding the edges of the wound in apposed condition comprises a contact adhesive.

56. A wound closure system as in claim 5, wherein the porous wound apposing member is a body formed of fibrous material.

12. A wound closure system comprising:

an elongate carrier member;

an adhesive delivery port formed in the carrier member;

a porous wound apposing bonding pad;

means mounting the bonding pad on the carrier member adjacent the adhesive delivery port;

means for affixing the carrier member on a patient; and

a source of flowable adhesive and a means for delivering the flowable adhesive to the adhesive delivery port.

13. A wound closure system as in claim 12, wherein the affixing means is a contact adhesive.

14. A wound closure system as in claim 12, wherein the adhesive delivery port comprises a first opening in the carrier member and a second opening in the carrier member spaced longitudinally from the first opening, said bonding pad being located adjacent said first and second openings.

15. A wound closure system as in claim 13, further comprising a removable protective strip overlying the contact adhesive.

16. A wound closure system as in claim 12, wherein the bonding pad is releasably secured on the carrier member.

17. A wound closure system as in claim 12, further comprising an anti-backflow membrane disposed between the carrier member and the bonding pad.

18. A wound closure system as in claim 17, wherein the anti-backflow membrane comprises a perforated sheet.

19. A wound closure system as in claim 12, further comprising a screen member overlying the bonding pad.

20. A wound closure system as in claim 19, wherein the screen member comprises a perforated sheet bonded to the carrier member.

21. A wound closure system as in claim 12, wherein the carrier member includes perforations therein positioned outwardly of the location of the bonding pad.

22. A wound closure system as in claim 12, further comprising an adhesive impervious barrier member disposed over a portion of a patient contact surface of the bonding pad.

23. A wound closure system as in claim 12, wherein the carrier comprises a strip having a raised portion and the bonding pad is positioned on the carrier member at the raised portion.

24. A wound closure system as in claim 12, wherein the carrier member includes a grasping area at one end thereof free of means for affixing the carrier member on a patient.

25. A wound closure system as in claim 12, wherein a plurality of bonding pads are mounted on the carrier member.

26. A wound closure system as in claim 25, wherein the bonding pads are disposed transversely on the carrier member.

27. A wound closure system as in claim 12, further comprising capillary ducts located at an interface between the carrier member and the bonding pad.

28. A wound closure system as in claim 27, wherein the capillary ducts are formed in the carrier member.

29. A wound closure system as in claim 12, wherein the carrier member is a strip having a first side, adapted to be placed in contact with a patient, and a second side opposed to the first side;

and the bonding pad has a first end portion disposed on the first side of the carrier member, an intermediate portion disposed on the second side of the carrier member, and a second end portion disposed on the first side of the carrier member.

30. A wound closure system as in claim 29, wherein the carrier member includes a pair of spaced openings and the intermediate portion of the bonding pad extends between said openings.

31. A wound closure system as in claim 30, wherein the bonding pad is secured to portions of the carrier member disposed between the openings and the carrier member includes a weakened separation portion extending between the openings.

32. A wound closure system as in claim 30, further comprising a slit in the carrier member extending substantially longitudinally between the openings.

33. A wound closure system as in claim 12, wherein the carrier member includes a transversely extending weakened portion adjacent each end of the bonding pad, for permitting ready removal of ends of the carrier member.

34. A wound closure system as in claim 12, wherein the adhesive is a cyanoacrylate.

35. A wound closure system as in claim 12, wherein the a source of flowable adhesive comprises an adhesive container, means mounting the adhesive container on the carrier member, a supply of flowable adhesive in the container and means for providing fluid communication between the container and the bonding pad.

36. A wound closure system as in claim 34, wherein the container comprises a flexible film and a pressure rupturable closure for maintaining the adhesive within the container.

37. A wound closure system as in claim 35, wherein the container is integrally formed in a portion of the carrier member.

57. A wound closure system as in claim 35, wherein the adhesive container comprises a pierceable layer and means for piercing the pierceable layer.

38. A wound closure system comprising:

a porous bonding pad;

a contact adhesive on one surface of the bonding pad for maintaining the bonding pad in wound apposing position on a patient; and

a flowable adhesive for application to the bonding pad for securing the bonding pad on a patient.

39. A wound closure system as in claim 38, wherein the bonding pad includes means on a second surface thereof, opposite the first surface, for indicating a location for applying the flowable adhesive to the bonding pad.

40. A wound closure system as in claim 38, further comprising a removable protective means disposed over the contact adhesive.

41. A method of wound apposition comprising:

placing an elongate member in engagement with a first wound margin;

holding the wound in apposition by drawing the member across the wound and engaging an opposed wound margin;

placing a porous bonding member at apposed wound margins with a first portion thereof disposed at a first wound margin and a second portion thereof disposed at a second wound margin; and

applying a flowable adhesive to the first and second portions of the bonding member and allowing the adhesive to adhere the bonding member to the respective wound margins.

42. A wound closure method as in claim 41, further comprising the step of removing the elongate member from the wound after the bonding member is adhered to the wound margins.

43. A wound closure method as in claim 41, wherein the elongate member and the bonding pad are simultaneously applied to the wound.

44. A wound closure method as in claim 41, wherein the adhesive comprises a cyanoacrylate.

50. A wound closure method as in claim 41, wherein the first and second wound margins comprise the skin of a patient.

45. A method of wound apposition comprising:

placing a first part of an elongate member in engagement with a first wound margin;

holding the wound in apposition by placing a second part of the elongate member in engagement with a second wound margin opposed to the first wound margin;

placing a porous bonding member at opposed wound margins with a first portion thereof disposed at the first wound margin and a second portion thereof disposed at the second wound margin; and

applying a flowable adhesive to the first and second portions of the porous bonding member and allowing the adhesive to adhere the porous bonding member to the respective wound margins.

46. A wound closure method as in claim 45, further comprising the step of removing the elongate member from the wound after the bonding member is adhered to the wound margins.

47. A wound closure method as in claim 45, wherein the elongate member and the porous bonding pad are simultaneously applied to the wound.

48. A wound closure method as in claim 45, wherein the adhesive comprises a cyanoacrylate.

49. A wound closure method as in claim 45, wherein the first and second wound margins comprise the skin of a patient.

51. A method of closing a wound comprising the steps of:

placing a porous bonding member at a wound site with a first part of the bonding member disposed on a first portion of tissue at the wound site and a second part of the bonding member disposed on a second portion of tissue at the wound site to be apposed with the first portion of tissue; and

applying a flowable adhesive to the first and second parts of the porous bonding member and allowing the adhesive to flow into the porous bonding member and adhere the porous bonding member to the first and second portions of tissue.

52. A method of closing a wound as in claim 51, further comprising the step of maintaining the first and second tissue portions apposed while the adhesive adheres the bonding member to said tissue portions.

53. A method of closing a wound as in claim 51, wherein the flowable adhesive is a cyanoacrylate.

54. A method of closing a wound as in claim 53, wherein the first and second portions of tissue comprise the skin of a patient.