Method and apparatus for automatically analyzing particles using plural analyzing modules

• US 5,260,027 A
• Filed: 04/30/1992
• Issued: 11/09/1993
• Est. Priority Date: 06/05/1991
• Status: Expired due to Fees

• Current Assignee: Toa Medical Electronics Co., Ltd.
• Original Assignee: Toa Medical Electronics Co., Ltd.
• Inventors: Kuroda, Toshiaki
• Primary Examiner(s): Housel, James C.
• Assistant Examiner(s): Le, Long V.
• Application Number:
  US07/876,425
• Time in Patent Office: 558 Days
• Field of Search: 422/81, 422/63, 422/100, 422/67, 422/103, 436/180, 436/179, 436/174, 436/52, 436/53, 436/54, 436/43, 436/55, 73/864.83, 73/864.84, 73/864.87, 73/864.21, 73/864.22, 73/863.31, 73/863.32
• US Class Current: 422/81
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 35/00603 Reinspection of samples
• CPC Class Codes: G01N 35/00732 Identification of carriers, materials or components in automatic analysers
• CPC Class Codes: G01N 35/0092 Scheduling
• CPC Class Codes: Y10T 436/11 Automated chemical analysis
• CPC Class Codes: Y10T 436/12 Condition responsive control
• CPC Class Codes: Y10T 436/25 including sample preparation
• CPC Class Codes: Y10T 436/25625 Dilution
• CPC Class Codes: Y10T 436/2575 Volumetric liquid transfer

Abstract

In blood examinations, first basic items such as the number of red blood cells, the number of white blood cells and the volume of hemoglobins are measured (primary examination), then, on the basis of the results thereof, further specific additional items are measured such as leukocyte classification and measurement of reticulocytes (secondary examination). In this case, the basic items are measured by the basic analyzing module and the results of the measurement are analyzed to judge whether additional items are necessary or not, and only specimens requiring additional items are measured in the additional analyzing module. The additional analyzing module is provided with a temporary sump for temporarily retaining the measuring solution from the measuring solution preparing device. Thus, the blood examination may be done efficiently.

Claims

1. An apparatus for automatically analyzing particles using a plurality of analyzing modules, said apparatus comprising:

a plurality of analyzing modules for measuring differing measuring items, one of said plurality of analyzing modules comprises a basic analyzing module having a measuring unit for measuring basic items, and the others of said plurality of analyzing modules comprising additional analyzing modules each having valve means and a measuring unit for measuring additional items, said basic analyzing module further having measuring solution preparing means for preparing a measuring solution for the basic analyzing module and a measuring solution for the additional analyzing modules, said additional analyzing modules each have a temporary sump for temporarily retaining its measuring solution, and each said temporary sump being disposed upstream of its respective measuring unit and connected to its respective measuring unit through said valve means,

a control means for controlling the function of the analyzing modules, and

an analyzing device for analyzing data from the analyzing modules,

wherein said control means serving to initiate operation of said additional analyzing modules based on the analysis performed by said basic analyzing module said analyzing device such that the measuring solution in any one of said temporary sumps is disposed of or transferred to its respective measuring unit for measuring additional items.

2. The apparatus according to claim 1, wherein said measuring solution preparing means includes a quantitative sampling means comprising a sampling valve having a plurality of elements for separating a sample liquid into slices, a sample suction probe connected to the sampling valve, and sample suction means connected to the sampling valve, said apparatus further comprising first liquid dispensing means connected to the sampling valve and said basic analyzing module, and second liquid dispensing means connected to the sampling valve and said additional analyzing modules.

3. The apparatus according to claim 1, wherein at least one additional analyzing module having a second temporary sump and a valve additionally disposed at the upstream side of its respective measuring unit.

4. The apparatus according to claim 2, wherein at least one additional analyzing module having a second temporary sump and a valve additionally disposed at the upstream side of the measuring unit.

5. The apparatus according to claim 1, wherein for each sample said control means effects one of the following:

a) measurement of basic items and measurement of additional items on the basis of the result of a judgement made relative to the measurement of the basic items;

b) measurement of basic items only; and

c) measurement of basic elements and measurement of additional elements.

6. The apparatus according to claim 2, wherein for each sample said control means effects one of the following:

a) measurement of basic items and measurement of additional items on the basis of the result of a judgement made relative to the measurement of the basic items;

b) measurement of basic items only; and

c) measurement of basic elements and measurement of additional elements.