CO.sub.2 mainstream capnography sensor

• US 5,261,415 A
• Filed: 07/12/1991
• Issued: 11/16/1993
• Est. Priority Date: 07/12/1991
• Status: Expired due to Fees

• Current Assignee: CIBA Vision Corporation (Novartis Ag)
• Original Assignee: CIBA Vision Corporation (Novartis Ag)
• Inventors: Dussault, Richard A.
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): Casler, Brian L.
• Application Number:
  US07/729,509
• Time in Patent Office: 858 Days
• Field of Search: 128/719, 128/633, 128/664, 128/716, 606/3, 73/23.21, 73/23.23, 73/23.3, 356/436-439, 422/84, 374/133
• US Class Current: 600/532
• CPC Class Codes: A61B 5/0836 Measuring rate of CO2 production
• CPC Class Codes: A61B 5/7242 using integration
• CPC Class Codes: G01N 21/3504 for analysing gases, e.g. multi-gas analysis

Abstract

A capnography system has a 4.2 micron LED emitter of narrow-band radiation having a center wavelength very close to the 4.26 micron absorption band of CO₂ breathing gas in a breathing tube. The radiation passes through windows in an insert in the breathing passage between the LED source and an infrared detector in an opposite side of the insert. A mirror is optionally placed in the opposite wall to reflect the radiation back to the detector which is then placed on the same side as the emitter. The LED emitter is pulsed at a low frequency repetition rate with a regulated voltage from a power supply. The detector output is applied to processing electronics which includes amplification and dual integrators that integrate the detector output on two signal paths, one the integration of each pulse and the other the integration of detector background with the two differences to provide self calibration against drift and noise. A heater heats the emitter, infrared detector, local electronics and the windows thereby stabilizing these temperature sensitive components to minimize the measured CO₂ value error to a few mm of mercury and to prevent condensation on the insert particularly in the windows. A second emitter is optionally used as a reference and/or to detect additional gas concentrations.

Claims

1. A capnography system comprising:

a breathing passage for breathing gases between a patient and an exhaust;

an optical path across said breathing passage permitting the transmission of radiation therethrough;

an LED source of pulsed radiation, positioned adjacent said breathing passage, for emitting radiation of approximately 4.2 micron wavelength and of a bandwidth encompassing the absorption band of CO₂ in said optical path;

a detector for pulsed radiation positioned adjacent said breathing passage for the receipt of radiation emitted by said LED source and to provide a pulsed waveform output in response to the received pulsed radiation from said LED source; and

processing electronics electrically connected to said detector, said processing electronics responsive to the pulsed waveform output provided by said detector and generating an output capnogram representation of the concentration of CO₂ in said breathing passage.

2. The capnography system of claim 1 further including an insert cooperative with said breathing passage having at least one window disposed in the optical path of said breathing passage adjacent said LED source and at least one opposite optical element disposed in the optical path across said breathing passage from said at least one window selected from a group consisting of a window and a reflector.

3. The capnography system of claim 2 wherein said window is of sapphire.

4. The capnography system of claim 1 wherein said LED source is an InAsSbP/InAs emitter.

5. The capnography system of claim 4 wherein said LED is packaged in a TO housing with a sapphire window.

6. The capnography system of claim 1 further including:

a heater cooperative with said detector for maintaining the temperature of the detector.

7. The capnography system of claim 6 wherein said heater has a regulator which maintains the detector temperature within a range to provide a maximum error of approximately 3 mmHg of CO₂ over eight hours in said capnogram representation.

8. The capnography system of claim 1 further including:

a heater disposed adjacent said breathing passage for applying heat to said optical path to prevent condensation on said optical path from vapor in said breathing passage.

9. The capnography system of claim 1 further including:

a housing with said LED source and said detector removably mounted on said breathing passage for positioning said LED source to emit radiation across said optical path and for positioning said detector to receive the emitted radiation.

10. The capnography system of claim 9 further including a heat source disposed within said housing providing heat to said optical path when said housing is mounted to said breathing passage and for temperature control of at least one of said source and detector.

11. The capnography system of claim 10 further including a heater regulator connected to said heater for maintaining a temperature of the detector in said housing within approximately 0.01°

C.

12. The capnography system of claim 1 wherein said processing electronics include:

a power supply connected to said LED source, said power supply being regulated in voltage to maintain a stable emission spectrum of radiation power level emitted by said LED source.

13. The capnography system of claim 1 wherein said processing electronics includes:

an amplifier connected to said detector to amplify the pulsed waveform output of said detector.

14. The capnography system of claim 13 wherein said amplifier is a surface mounted amplifier.

15. The capnography system of claim 1 wherein said processing electronics includes:

an integrator connected to integrate the pulsed waveform output of said detector above a repetitively adjusted baseline.

16. The capnography system of claim 15 wherein said processing electronics includes:

a sample and hold circuit connected to said integrator for the integrated pulse output of the detector.

17. The capnography system of claim 16 wherein said sample and hold circuit maintains each integrated pulse output between output pulses of the detector and further including:

a low-pass filter connected to said sample and hold circuit having a cut-off point below a pulse repetition rate of pulse emissions from the LED source.

18. The capnography system of claim 1 wherein:

said LED source includes a source of reference radiation sensed by said detector; and

said processing electronics provides the capnogram representation with compensation for the reference radiation as sensed by the detector.

19. The capnography system of claim 1 wherein:

said LED source includes a source of radiation for a further gas in said breathing passage which radiation is sensed by said detector; and

said processing electronics provides an output capnogram representation of the concentration of the further gas in the breathing passage.

20. A capnography system comprising:

a breathing passage for breathing gases between a patient and a breathing gas source and an exhaust;

an LED source of pulsed radiation positioned adjacent said breathing passage, the radiation having a narrow band emission spectrum coinciding with an absorption band of CO₂ gas within said breathing passage;

a detector positioned adjacent said breathing passage for detecting pulsed radiation from said LED source through said passage and providing a pulsed waveform output in response to the reception of pulsed radiation from said LED source;

a mirror mounted adjacent said breathing passage;

an optical access disposed transversely through said breathing passage enabling the transmission of radiation across said breathing passage between said LED source and said detector by reflection of the pulsed radiation by said mirror from an opposite side to provide multiple traversals through the breathing gas by said radiation;

processing electronics electrically connected to said detector, said processing electronics responsive to the pulsed waveform output provided by said detector and generating an output capnogram representation of the concentration of CO₂ in said breathing passage.

21. The capnography system of claim 20 wherein said optical access includes an insert disposed in said breathing passage adjacent said detector defining at least one window opposing said mirror across breathing passage.

22. The capnography system of claim 21 wherein each said window is of sapphire.

25. The capnography system of claim 20 further including:

a heater positioned adjacent said detector for maintaining the temperature of the detector.

26. The capnography system of claim 25 wherein said heater further includes a controller for maintaining the detector temperature within a range to provide a maximum error of approximately 3 mmHg of CO₂ over eight hours in said capnogram representation.

27. The capnography system of claim 20 further including:

a heater positioned adjacent said optical access for preventing condensation on said optical access mirror from vapor in said breathing passage.

28. The capnography system of claim 20 further including:

a housing for said LED source and said detector removably mounted with respect to said optical access to place said source and detector in radiation transmission and receiving relationship to gases in said breathing passage when mounted to said optical access.

29. The capnography system of claim 28 further including a heat source mounted within said housing providing heat to said optical access and to at least one of said source and detector.

30. The capnography system of claim 29 including a heater regulator cooperative with said housing for maintaining a temperature within said housing within approximately 0.01°

C.

31. The capnography system of claim 20 wherein said processing electronics includes:

a power supply for said LED source cooperative with said processing electronics regulated in voltage to maintain an emission spectrum of said LED source.

32. The capnography system of claim 20 wherein said processing electronics includes:

an amplifier connected to said processing electronics and in close proximity to the detector for amplifying the detector pulsed waveform output.

33. The capnography system of claim 32 wherein said amplifier is a surface mounted amplifier.

34. The capnography system of claim 20 wherein said processing electronics includes:

an integrator connected to said processing electronics for integrating the pulsed waveform output of the detector above a repetitively adjusted baseline.

35. The capnography system of claim 34 wherein said processing electronics includes:

a sample and hold circuit connected to said processing electronics for holding the integrated pulsed waveform output of the detector.

36. The capnography system of claim 35 wherein said sample and hold circuit maintains each integrated pulse output between output pulses of the detector and further including:

a low pass filter having a cut-off point below a pulse repetition rate of pulsed emissions from the LED source.

37. The capnography system of claim 20 wherein:

said LED source includes a source of reference radiation sensed by said detector; and

said processing electronics provides the capnogram representation with compensation for the reference radiation as sensed by the detector.

38. The capnography system of claim 20 wherein:

said LED source further includes a source of radiation having a wavelength within the absorption band of a further gas in said breathing passage which radiation is sensed by said detector; and

said processing electronics provides an output capnogram representation of the concentration of the further gas in the breathing passage.

23. The capnography system of clam 20 wherein said LED source is an InAsSbP/InAs emitter.

24. The capnography system of claim 23 wherein said LED source is packaged in a TO housing with a sapphire window.

39. A capnography system comprising:

a breathing passage for breathing gases between a patient and a breathing gas source and an exhaust;

an LED source of pulsed radiation positioned adjacent said breathing passage, the radiation having a narrow band emission spectrum coinciding with an absorption band of CO₂ gas within said breathing passage;

a detector positioned adjacent said breathing passage for detecting pulsed radiation from said LED source through said passage and providing a pulsed waveform output in response to the reception of pulsed radiation from said LED source;

an optical access disposed transversely through said breathing passage providing for the transmission of radiation through said breathing passage between said LED source and said detector;

processing electronics electrically connected to said detector, said processing electronics responsive to the pulsed waveform output provided by said detector and generating an output capnogram representation of the concentration of CO₂ in said breathing passage, said processing electronics further including a first integrator for providing an integration of the detector pulsed waveform output above an adjusted baseline.

40. The capnography system of claim 39 wherein said optical access includes an insert disposed in said breathing passage having at least one window disposed adjacent said LED source and at least one opposite optical element selected from the group consisting of a window and a reflector disposed across said breathing passage from said at least one window.

41. The capnography system of claim 39 further including:

a housing for said LED source and said detector removably mounted on said optical access to place said LED source and detector in radiation transmission and receiving relationship to gases in said breathing passage when mounted to said optical access.

42. The capnography system of claim 41 further including a heat source disposed within said housing providing heat to said optical access and to at lest one of said source and detector.

43. The capnography system of claim 42 including a heater regulator connected to said heat source for maintaining a temperature of the detector within said housing within approximately 0.01°

C.

44. The capnography system of claim 39 wherein said processing electronics includes:

a second integrator for integrating an output of the detector between pulses; and

a difference circuit for taking a difference of the integrations of said first and second integrators.

45. The capnography system of claim 44 wherein said processing electronics includes:

a sample and hold circuit connected to said processing electronics for holding the difference of the difference circuit.

46. The capnography system of claim 45 wherein said sample and hold circuit maintains each integrated pulse output between output pulses of the detector and further including:

a low pass filter connected to said circuit having a cut-off point below a pulse repetition rate of pulsed emissions from the LED source.

47. A capnography system comprising:

a breathing passage for breathing gases between a patient and a breathing gas source and an exhaust;

an LED source of pulsed radiation positioned adjacent said breathing passage, the radiation having a wavelength within the absorption band of CO₂ gas within said breathing passage;

a detector positioned adjacent said breathing passage for detecting pulsed radiation from said LED source and providing a pulsed waveform output in response to the detected pulsed radiation from said LED source;

an optical access disposed transversely through said breathing passage providing the transmission of radiation across said breathing passage between said LED source and said detector;

processing electronics electrically connected to said detector, said processing electronics responsive to the pulsed waveform output provided by said detector and generating an output capnogram representation of the concentration of CO₂ in said breathing passage, said processing electronics further including a first integrator for providing an integration of the detector pulsed waveform output above an adjusted baseline;

a heater for at least one of said detector and source to limit an error in the representation of CO₂ ; and

a housing cooperative with said breathing passage for said heater, said source, and said detector for maintaining the temperature thereof.

48. The capnography system of claim 47 wherein said heater further includes control means for maintaining said temperature within a range to provide a maximum error of approximately 3 mmHg of CO₂ over eight hours in said capnogram representation.

49. The capnography system of claim 48 wherein said heater is in direct thermal contact with said optical access to prevent condensation on said optical access from vapor in said breathing passage.

50. The capnography system of claim 47 further including:

a housing cooperative with said breathing passage for said heater, said LED source, and said detector selectively mountable with said optical access to place said source and detector in radiation transmission and receiving relationship to gases in said breathing passage when mounted to said optical access.

51. The capnography system of claim 50 further including a conduit cooperative with said heater for directing heat from said heater within said housing to said optical access and to at least one of said source and detector.

52. The capnography system of claim 51 including a heater regulator connected to said heater for maintaining a temperature of the detector in said housing within approximately 0.01°

C.