Method and apparatus for extracting injectable collagen from adipose tissue

• US 5,261,612 A
• Filed: 10/09/1991
• Issued: 11/16/1993
• Est. Priority Date: 10/09/1991
• Status: Expired due to Fees

• Current Assignee: Newman-Ftaiha, Inc.
• Original Assignee: Newman-Ftaiha, Inc.
• Inventors: Ftaiha, Zaki
• Primary Examiner(s): Rosenbaum, Mark
• Assistant Examiner(s): HUSAR, JOHN
• Application Number:
  US07/773,469
• Time in Patent Office: 769 Days
• Field of Search: 241/2, 241/24, 241/79, 241/301, 241/21, 241/20, 241/62, 241/81, 241/199.12, 241/46.02, 241/46.06, 530/356
• US Class Current: 241/2
• CPC Class Codes: A61F 2310/00365 Proteins; Polypeptides; Degradation products thereof
• CPC Class Codes: A61L 27/24 Collagen

Abstract

A method and apparatus for extracting injectable collagen from human adipose tissue, such as removed by liposuction procedures. The apparatus includes a clear container with inlet and outlet fittings to be attached to the suction line of a liposuction machine to collect globules of adipose tissue. The container has a needle-like rod disposed in its center and an electric motor and belt drive to rotate the rod at a speed sufficient to cause interstitial reticular fiber from adipose tissue to adhere to and wrap around the rod. Water may then be flowed in through the inlet fitting and drawn out through the outlet fitting to flush the adipose tissue out of container, leaving the reticular fibers on the rod. The rod is then retracted (lowered) through a sleeve which has a rotating chopping blade, scrapping the fiber into a cup area of chopping blades. A pharmaceutical carrier such as saline solution is injected into the container. The rotating chopping blades are driven by the motor and belt to emulsify the reticular fibers into the saline solution. The emulsion is then extracted for use as injectable collagen.

Claims

1. A method of extracting injectable collagen from human adipose tissue, comprising the steps of:

(a) collecting globules of human adipose tissue in a container;

(b) isolating interstitial reticular fiber tissue from the adipose tissue;

(c) removing the adipose tissue from the container while retaining the isolated reticular fiber tissue inside the container;

(d) introducing a pharmaceutical carrier liquid into the container;

(e) chopping the reticular fibers sufficiently fine to emulsify the fiber tissue in the carrier;

(g) removing the emulsion from the container for use as injectable collagen.

2. A method as in claim 1, further comprising:

collecting the adipose tissue from a suction line of a liposuction device.

3. A method as in claim 1, further comprising

isolating interstitial reticular fiber tissue from the globules of adipose tissue by spinning a needle-like member in the adipose tissue such that reticular fiber tissue adheres to the member.

4. A method as in claim 1, further comprising:

removing the adipose tissue from the container while retaining the isolated reticular fiber inside the container by flushing the adipose tissue out of the container with water.

5. An apparatus for extracting injectable collagen from human adipose tissue, comprising:

a container for collecting globules of human adipose tissue;

means for isolating reticular fibers from the adipose tissue inside the container;

means for removing the adipose tissue from the container while retaining the isolated reticular fiber inside the container;

means for introducing a pharmaceutical carrier liquid into the container;

a cutting and blending device for reducing the reticular fibers sufficiently fine to emulsify the reticular tissue in the carrier; and

means for extracting the emulsion for use as injectable collagen.

6. An apparatus as in claim 5, wherein the means for isolating reticular fibers from the adipose tissue inside the container comprises:

a needle-like rod disposed within the container to be surrounded by adipose tissue; and

means for rotating the rod at a speed sufficient to isolate interstitial reticular fiber from the globules of adipose tissue.

7. An apparatus as in claim 5, wherein the container is placed in the suction line of a liposuction device between a suction probe and a suction source, to collect globules of adipose tissue removed from a human patient by the suction probe.

8. An apparatus as in claim 7, wherein the means for isolating reticular fibers from the adipose tissue inside the container comprises:

a needle-like rod disposed within the container to be surrounded by adipose tissue; and

means for rotating the rod at a speed sufficient to isolate interstitial reticular fiber from the globules of adipose tissue.

9. An apparatus as in claim 7, wherein the container is a vessel of optically clear material having inlet and outlet fittings for connection to the suction line of a liposuction device.

10. An apparatus for extracting injectable collagen from human adipose tissue, comprising:

a support structure for supporting a needle-like rod in a vertical orientation with freedom of movement in the vertical direction and rotational freedom around the rod'"'"'s long axis;

an open-mouthed container placed in the suction line of a liposuction device between a suction probe and the suction source, and to collect globules of adipose tissue removed from a human patient by the suction probe;

means for attaching the container to the support structure such that when the container is attached to the structure, the mouth of the container is closed by the structure and the rod is aligned to move vertically into the container;

means for moving the rod vertically into the container;

means for rotating the rod at a speed sufficient to cause interstitial reticular fiber from the globules of adipose tissue to adhere to and wrap around the rod;

a cutting and blending device comprising rotating blades surrounding the rod within the container;

means for lowering the rod vertically through the cutting device to scrape reticular fiber from the rod into the cutting and blending device;

means for introducing a pharmaceutical carrier liquid into the container;

means for rotating the blades of the cutting and blending device to emulsify the reticular fibers into the carrier; and

means to remove the emulsion from the carrier as an injectable collagen.