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Method and apparatus for determination of a constituent in a fluid

  • US 5,269,891 A
  • Filed: 01/26/1993
  • Issued: 12/14/1993
  • Est. Priority Date: 03/09/1989
  • Status: Expired due to Fees
First Claim
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1. A method of amperemetric detection of at least one constituent of a fluid sample of animal or human whole blood by means of a measuring apparatus containing an integrated electrode device including at least one enzyme sensor electrode and a reference electrode having an exposed surface part at a free end portion of the integrated electrode device and extending longitudinally through said end portion, said method being characterized in that the reference electrode used is an Ag/AgCl electrode working at a chloride ion concentration of about 145 meq/l and that before applying the sample on the exposed surface of the electrode device, said electrode device is moved longitudinally outward by an increment and subsequently the outer end section of said free end portion of the integrated electrode device is removed by means of removing means mounted movably on the measuring apparatus, so as to provide a new exposed surface part of the integrated electrode device, and that subsequently said new exposed surface part of the integrated electrode device is exposed to said fluid sample, so as to generate a measuring signal representative of said constituent of the sample.

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