Automatic sample analyzer

• US 5,270,006 A
• Filed: 09/03/1991
• Issued: 12/14/1993
• Est. Priority Date: 09/05/1990
• Status: Expired due to Term

• Current Assignee: Kyoto Daiichi Kagaku Company Limited
• Original Assignee: Kyoto Daiichi Kagaku Company Limited
• Inventors: Takagi, Yasumitsu, Nishimura, Hideki, Uchigaki, Takatoshi
• Primary Examiner(s): Wityshyn, Michael G.
• Assistant Examiner(s): Beisner, William H.
• Application Number:
  US07/754,002
• Time in Patent Office: 833 Days
• Field of Search: 422/56, 422/57, 422/62, 422/58, 422/63, 422/65, 422/66, 422/104, 422/99, 436/808, 436/810, 435/287, 435/288, 435/291, 435/289, 435/805, 435/808, 221/123, 221/131, 221/198, 221/287
• US Class Current: 422/63
• CPC Class Codes: G01N 2035/00039 Transport arrangements specific to flat sample substrates, e.g. pusher blade
• CPC Class Codes: G01N 2035/00089 Magazines
• CPC Class Codes: G01N 2035/00118 for multiple tests
• CPC Class Codes: G01N 2035/00752 bar codes
• CPC Class Codes: G01N 35/00029 provided with flat sample substrates, e.g. slides G01N35/028 takes precedence

Abstract

An automatic sample analyzer comprising, a plurality of sticks which have a plurality of reagent portions corresponding to different examination items so as to be divided into a plurality of groups of sticks by combinations of the examination items, a plurality of cassettes each having an outlet and a discriminatory mark, the discriminatory mark corresponding to one of the group of the sticks so as to accommodate the one of the group of the sticks, a removal device for automatically taking a desired one of the sticks of the cassettes by using a single removal mechanism.

Claims

1. An automatic sample analyzer comprising:

a plurality of sticks each having a plurality of different reagent portions, the sticks being divided into a plurality of groups of sticks and the groups being for different examination items;

a plurality of cassettes, each cassette having a plurality of said sticks from the same group and each cassette comprising,

a bottom face,

an outlet adjacent the bottom face and a slit defined in the bottom face, said outlet and said slit being configured such that the sticks can be discharged through the outlet by a push pin which travels within the slit,

a slide plate movable between an upper end and the bottom face of the cassette, said sticks being positioned between said slide plate and said bottom face,

a torsion spring provided in said cassette, the torsion spring being provided between the upper end of the cassette and the slide plate, the torsion spring urging the slide plate away from the upper end of the cassette,

an engageable claw provided on said slide plate,

an engageable member provided on an upper portion of a side of said cassette, the engageable claw being detachably engageable with the engageable member to at least temporarily hold the slide plate in a selected position, and

a removal device including a single removal mechanism and push pin for taking a desired one of said sticks out of said cassettes by using the single removal mechanism, said pin being movable in a horizontal direction orthogonally to the cassette through the slit in the cassette;

an examining device for analyzing the reagent portions of the sticks;

a conveyor for receiving said desired stick taken out of said cassette by said removal device and for conveying said desired stick to said examining device.

2. The automatic sample analyzer as claimed in claim 1, wherein each of said slits has a predetermined length and a predetermined width, the pin being movable along the length of the slit to remove said sticks one-by-one from the cassette, said sticks each having a generally uniform width and the width of the slit being less than the width of the sticks, the bottom face of the cassette supporting the sticks and preventing deformation thereof.

3. The automatic sample analyzer as claimed in claim 1, wherein each of the sticks has a face on which first and second pads are provided, the first and second pads being provided on opposite ends of the face of the sticks, the plurality of reagent portions being provided between said first and second pads on the face of each stick, the first and second pads having a thickness greater than a thickness of each of the reagent portions.

4. The automatic sample analyzer as claimed in claim 3, wherein the first pad is disposed closer to said outlet than the second pad when the stick is in the cassette, neighboring reagent portions being provided adjacent to the first pad and to the second pad, a length of each pad being defined in a direction between the ends of the stick and the length of the first pad being larger than a distance between said first pad and the neighboring reagent portion and being larger than a distance between the second pad and the neighboring reagent portion.

5. An automatic sample analyzer comprising:

a plurality of sticks each having a plurality of different reagent portions at predetermined positions, the sticks being divided into a plurality of groups;

a plurality of cassettes, each cassette having a plurality of said sticks from the same group and each cassette comprising,

a bottom face,

an outlet adjacent the bottom face and a slit defined in the bottom face, said outlet and said slit being configured such that the sticks can be discharged through the outlet by a push pin which travels within the slit,

a slide plate movable between an upper end and the bottom face of the cassette, said sticks being positioned between said slide plate and said bottom face,

a torsion spring provided in said cassette, the torsion spring being provided between the upper end of the cassette and the slide plate, the torsion spring urging the slide plate away from the upper end of the cassette,

an engageable claw provided on said slide plate,

an engageable member provided on an upper portion of a side of said cassette, the engageable claw being detachably engageable with the engageable member to at least temporarily hold the slide plate in a selected position, and

a discriminatory mark disposed on one side of the slit, said discriminatory mark corresponding to one of said groups for said sticks;

a cassette accommodating section accommodating a plurality of said cassettes juxtaposed to each other;

a base assembly including a push pin and a reader, the base assembly being arranged below said cassette accommodating section, the push pin being constructed so as to push individual sticks out of each cassette by traveling along the slits in the cassettes to thereby remove the sticks from the cassettes, the reader being constructed so as to read said discriminatory mark on the cassettes;

a drive mechanism for moving the reader so as to read the discriminatory marks of each cassette in the cassette accommodating section and provide a position of each group of sticks within the cassette accommodating section, and for driving said base assembly in a horizontal direction orthogonally to the cassettes such that said base assembly pushes the sticks one-by-one out of the cassettes; and

a dripping section for receiving sticks removed from the cassettes by the base assembly, said dripping section including dripping means for dripping a sample on each of the reagent portions of said sticks received in said dripping section, said sample dripped on each of said reagent portions being examined by color comparison.

6. The automatic sample analyzer as claimed in claim 5, wherein each of said slits has a predetermined length and a predetermined width, the pin being movable along the length of the slit to remove said sticks one-by-one from the cassette, said sticks each having a generally uniform width and the width of the slit being less than the width of the sticks, the bottom face of the cassette supporting the sticks and preventing deformation thereof.

7. The automatic sample analyzer as claimed in claim 5, wherein each of the sticks has a face on which first and second pads are provided, the first and second pads being provided on opposite ends of the face of the sticks, the plurality of reagent portions being provided between said first and second pads on the face of each stick, the first and second pads having a thickness greater than a thickness of each of the reagent portions.

8. The automatic sample analyzer as claimed in claim 7, wherein the first pad is disposed closer to said outlet than the second pad when the stick is in the cassette, neighboring reagent portions being provided adjacent to the first pad and to the second pad, a length of each pad being defined in a direction between the ends of the stick and the length of the first pad being larger than a distance between said first pad and the neighboring reagent portion and being larger than a distance between the second pad and the neighboring reagent portion.

9. A cassette and a plurality of sticks which are accommodated in the cassette comprising:

a bottom face;

an outlet adjacent the bottom face and a slit defined in the bottom face, said outlet and said slit being configured such that the sticks can be discharged through the outlet by a push pin which travels within the slit;

a slide plate movable between an upper end and the bottom face of the cassette, said sticks being positioned between said slide plate and said bottom face;

a torsion spring provided in said cassette, the torsion spring being provided between the upper end of the cassette and the slide plate, the torsion spring urging the slide plate away from the upper end of the cassette;

an engageable claw provided on said slide plate; and

an engageable member provided on an upper portion of a side of said cassette, the engageable claw being detachably engageable with the engageable member to at least temporarily hold the slide plate in a selected position.

10. The cassette and plurality of sticks as claimed in claim 9, wherein each of said slits has a predetermined length and a predetermined width, the pin being movable along the length of the slit to remove said sticks one-by-one from the cassette, said sticks each having a generally uniform width and the width of the slit being less than the width of the sticks, the bottom face of the cassette supporting the sticks and preventing deformation thereof.

11. The cassette and plurality of sticks as claimed in claim 9, wherein each of the sticks has a face on which first and second pads are provided, the first and second pads being provided on opposite ends of the face of the sticks, a plurality of reagent portions being provided between said first and second pads on the face of each stick, the first and second pads having a thickness greater than a thickness of each of the reagent portions.

12. The cassette and plurality of sticks as claimed in claim 11, wherein the first pad is disposed closer to said outlet than the second pad when the stick is in the cassette, neighboring reagent portions being provided adjacent to the first pad and to the second pad, a length of each pad being defined in a direction between the ends of the stick and the length of the first pad being larger than a distance between said first pad and the neighboring reagent portion and being larger than a distance between the second pad and the neighboring reagent portion.