×

Method for producing protein microspheres

  • US 5,271,961 A
  • Filed: 06/23/1992
  • Issued: 12/21/1993
  • Est. Priority Date: 11/06/1989
  • Status: Expired due to Fees
First Claim
Patent Images

1. A method for producing protein microspheres comprising the steps of:

  • a) contacting a prolamine solution, wherein the prolamine solution contains at least one type of prolamine and a compound to be incorporated into the microspheres, with a second liquid, wherein the second liquid is of limited miscibility with the prolamine solvent such that the second liquid does not form a stable homogeneous solution with the prolamine solvent and does not dissolve the prolamine, in a ratio of prolamine solution to second liquid of at least 1;

    20, to form a prolamine-non-solvent mixture;

    b) agitating the prolamine-non-solvent mixture to form a dispersion of the prolamine solution in the second liquid at a temperature of less than about 65°

    C.; and

    c) removing the prolamine solvent to form stable prolamine microspheres without crosslinking or heat denaturation.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×