Gel-in-matrix containing a fractured hydrogel
First Claim
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1. A gel-in-matrix combination comprising a three-dimensional porous support matrix and a porous fractured hydrogel fixedly disposed therein, in which said fractured hydrogel has:
- (a) a void volume of about 10-90%; and
(b) a plurality of porous fractures comprising channels having a mean characteristic dimension of about 0.1-1,000 μ
m.
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Abstract
A three dimensional porous matrix, such as a reticulated open-cell foam, having within its matrix structure a mechanically-fractured hydrogel containing a network of fracture channels. The mechanically-fractured hydrogel may be a gel that has been partially dewatered by compression of the gel in situ.
The porosity of the gel-in-matrix makes it useful for chromatographic applications and for immobilization of biologically-active components, where efficient, intimate contact of the hydrogel with a liquid medium is important.
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Citations
50 Claims
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1. A gel-in-matrix combination comprising a three-dimensional porous support matrix and a porous fractured hydrogel fixedly disposed therein, in which said fractured hydrogel has:
- (a) a void volume of about 10-90%; and
(b) a plurality of porous fractures comprising channels having a mean characteristic dimension of about 0.1-1,000 μ
m. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50)
- (a) a void volume of about 10-90%; and
Specification