Medication delivery pen having improved dose delivery features

• US 5,279,585 A
• Filed: 02/04/1992
• Issued: 01/18/1994
• Est. Priority Date: 02/04/1992
• Status: Expired due to Term

• Current Assignee: Becton, Dickinson & Co
• Original Assignee: Becton, Dickinson & Co
• Inventors: Balkwill, David
• Primary Examiner(s): Rosenbaum, C. Fred
• Assistant Examiner(s): Polutta, Mark O.
• Application Number:
  US07/830,816
• Time in Patent Office: 714 Days
• Field of Search: 604/187, 604/218, 604/224, 604/207-211, 604/232, 604/246, 604/157, 222/386, 222/390, 222/391, 222/43, 222/46, 222/47, 222/48, 222/336, 222/309
• US Class Current: 604/207
• CPC Class Codes: A61M 2205/581 by audible feedback
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31541 Means preventing setting of a dose beyond the amount remaining in the cartridge
• CPC Class Codes: A61M 5/31543 piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
• CPC Class Codes: A61M 5/31553 without axial movement of dose setting member
• CPC Class Codes: A61M 5/31568 Means keeping track of the total dose administered, e.g. since the cartridge was inserted
• CPC Class Codes: A61M 5/3158 performed by axially moving actuator operated by user, e.g. an injection button

Abstract

An injection device is provided for injecting fluids such as insulin within body tissue. The device includes a housing, a piston rod movably mounted within the housing, and a dose setting mechanism for controlling the movement of the piston rod with respect to a fluid containing cartridge removably positioned within the housing. The dose setting mechanism includes a units counter ring and a tens counter ring. A transmission key is provided for selectively coupling the units and tens counter rings so that they rotate together only during selected portions of the dose setting procedure. The piston rod includes a plunger and a lead screw slidably positioned within the plunger. The plunger and lead screw are coupled by a pair of half nuts. The half nuts may be uncoupled from the lead screw in order to allow it to slide freely with respect to the plunger. A new cartridge may accordingly be installed quickly and easily as the lead screw is easily displaced by a new cartridge.

Claims

1. An injection device for injecting selected dosages of fluid, comprising:

an elongate housing;

means for mounting a fluid containing cartridge of the type including an internal piston to said housing;

manually operable piston moving means including a piston rod axially movably mounted within said housing for displacing fluid from a cartridge by moving said piston is said cartridge;

dose setting means for selecting the amount of fluid to be delivered by said device including a manually rotatable unit counter ring, a tens counter ring positioned in adjoining relation to said units counter ring, and transmission means for connecting said units counter ring and said tens counter ring, said transmission means including means for causing said tens counter ring to rotate a selected number of degrees upon rotation of said units counter ring through a selected angular displacement; and

means responsive to said dose setting means for controlling the axial movement of said piston rod such that the distance said piston rod can be moved is dependent upon the rotational position of said units and tens counter rings.

2. An injection device as described in claim 1 including means for disengaging said transmission means from said tens counter ring once said tens counter ring has rotated through said selected number of degrees.

3. An injection device as described in claim 1 wherein said transmission means include a transmission key positioned within said housing and means for urging said key into engagement with said tens counter ring when said units counter ring is in selected rotational position.

4. An injection device as described in claim 3 wherein said piston moving means further includes a plunger connected to said piston rod and extending through said units and tens counter rings, and a zero detection clip positioned at least partially between said plunger and said units counter ring, at least one of said units and tens counter rings including means for urging said zero detection slip into engagement with said plunger, thereby holding said plunger in a selected axial position with respect to said housing, said units counter ring being engaged to and rotatable with said plunger

5. An injection device as described in claim 4 wherein said plunger includes a plurality of elongate ribs extending radially outwardly therefrom, said zero detection clip including means for engaging said ribs so that a clicking sound is produced as said plunger is rotated with respect to said housing.

6. An injection device as described in claim 5 wherein said zero detection clip includes means for engaging said tens counter ring such that a clicking sound is produced as said tens counter ring is rotated about said zero detection clip.

7. An injection device as described in claim 4 wherein said zero detection clip includes a spring member, at least one of said units and tens counter rings including means for urging said spring member into engagement with said plunger.

8. An injection device as described in claim 4 wherein said piston rod is a lead screw positioned at least partially within said plunger and slidable axially therein.

9. An injection device as described in claim 1 further including an elongate fluid containing cartridge having an internal piston at its proximal end and a pierceable seal at its distal end defining a reservoir for said fluid, said cartridge being movably mounted in said device.

10. An injection device as described in claim 9 further comprising a needle assembly including an elongate cannula and a cup shaped hub, said cannula having a sharp proximal end, a sharp distal end and a lumen therethrough, said cup shaped hub holding said cannula so that said sharp proximal end of said cannula projects outwardly from the interior of said cup-shaped hub, said needle assembly being removably attached to said device so that said sharp proximal end pierces said pierceable seal of said cartridge so that said lumen is in fluid communication with the fluid in said cartridge.

11. An injection device as described in claim 1 further comprising:

a plunger portion of said piston moving means positioned at least partially within said housing;

a lead screw portion of said piston rod positioned at least partially within said plunger and axially slidable therein;

means for threadably engaging said lead screw;

means for selectively moving said means for threadably engaging said lead screw into and out of engagement with said lead screw, whereby said lead screw is freely slidable with respect to said plunger when said means for threadably engaging said lead screw are disengaged from said lead screw, said lead screw and plunger being slidable as a unit with respect to said housing when said means for threadably engaging said lead screw are engaged with said lead screw.

12. A device as described in claim 11 wherein said means for threadably engaging said lead screw include a pair of at least partially threaded half nuts positioned in opposing relation to each other within said housing with the threaded portion of said half nut facing said lead screw.

13. A device as described in claim 12 wherein said means for moving said half nuts include a rotatable locking ring, said locking ring including an elliptical inner wall, wherein rotation of said locking ring causes said inner wall of said locking ring to contact said half nuts and move said half nuts to a position wherein said threaded portion of said half nuts contacts said lead screw.