Use of oral diazoxide for the treatment of disorders in glucose metabolism
First Claim
1. A method for normalizing blood glucose and insulin levels as measured by an oral glucose tolerance test in an individual exhibiting normal fasting blood glucose and insulin levels and exhibiting in an oral glucose tolerance test elevated glucose levels and at least one insulin level abnormality selected from the group consisting of a delayed insulin peak, an exaggerated insulin peak and a secondary elevated insulin peak, said method comprising administering diazoxide to said individual before ingestion of a food source in an amount effective to normalize said blood glucose and insulin levels, wherein said diazoxide is administered in an amount from about 0.4 to about 0.8 mg/kg body weight before each meal.
0 Assignments
0 Petitions
Accused Products
Abstract
A method is disclosed for normalizing blood glucose and insulin levels as measured by an oral glucose tolerance test in an individual exhibiting normal fasting blood glucose and insulin levels and exhibiting in an oral glucose tolerance test elevated glucose levels and at least one insulin level abnormality selected from the group consisting of a delayed insulin peak, an exaggerated insulin peak and a secondary elevated insulin peak. The method comprises administering diazoxide to the individual before ingestion of a food source in an amount effective to normalize the blood glucose and insulin levels. Diazoxide is administered in an amount from about 0.4 to about 0.8 mg/kg body weight before each meal.
-
Citations
9 Claims
- 1. A method for normalizing blood glucose and insulin levels as measured by an oral glucose tolerance test in an individual exhibiting normal fasting blood glucose and insulin levels and exhibiting in an oral glucose tolerance test elevated glucose levels and at least one insulin level abnormality selected from the group consisting of a delayed insulin peak, an exaggerated insulin peak and a secondary elevated insulin peak, said method comprising administering diazoxide to said individual before ingestion of a food source in an amount effective to normalize said blood glucose and insulin levels, wherein said diazoxide is administered in an amount from about 0.4 to about 0.8 mg/kg body weight before each meal.
Specification