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Affinity peptides

  • US 5,284,933 A
  • Filed: 02/22/1988
  • Issued: 02/08/1994
  • Est. Priority Date: 03/10/1987
  • Status: Expired due to Term
First Claim
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1. A fusion protein comprising a biologically active polypeptide or protein linked by its amino- and/or carboxyl-terminus to one or two affinity peptides, which affinity peptides have the formula


  • space="preserve" listing-type="equation">R.sup.1 --(His).sub.2-6 --R.sup.2,
wherein R1 is hydrogen or a peptide chain formed from about 1 to about 30 amino acids; and

R2 is Q, Q-Ile-Glu-Gly-Arg- or Q-Asp-Asp-Asp-Asp-Lys, where Q is a peptide bond or a peptide chain formed from about 1 to about 30 amino acids.

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