Electron spin resonance enhanced MRI using an echo planar imaging technique
First Claim
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1. A method of electron spin resonance enhanced magnetic resonance imaging of a subject performed by an echo planar imaging technique, said method comprising the following steps:
- (a) exposing said subject to a first radiation of a frequency selected to excite an electron spin resonance transition in a paramagnetic species in said subject,(b) exposing said subject to at least one pulse of a second radiation of a frequency selected to excite nuclear spin transitions in selected nuclei in said subject,(c) imposing on said subject at least one spatial information encoding magnetic field gradient,(d) imposing on said subject a series of magnetic field read gradient pulses, said gradient pulses or sets of said gradient pulses within said series being of alternating polarities,(e) during at least part of the time said read gradients are imposed, detecting the magnetic resonance signal from said selected nuclei, and(f) generating from said detected signals an image of at least part of said subject.
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Abstract
There is provided an improved magnetic resonance imaging procedure which essentially combines electron spin resonance enhanced MRI with echo planar imaging MRI.
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Citations
11 Claims
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1. A method of electron spin resonance enhanced magnetic resonance imaging of a subject performed by an echo planar imaging technique, said method comprising the following steps:
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(a) exposing said subject to a first radiation of a frequency selected to excite an electron spin resonance transition in a paramagnetic species in said subject, (b) exposing said subject to at least one pulse of a second radiation of a frequency selected to excite nuclear spin transitions in selected nuclei in said subject, (c) imposing on said subject at least one spatial information encoding magnetic field gradient, (d) imposing on said subject a series of magnetic field read gradient pulses, said gradient pulses or sets of said gradient pulses within said series being of alternating polarities, (e) during at least part of the time said read gradients are imposed, detecting the magnetic resonance signal from said selected nuclei, and (f) generating from said detected signals an image of at least part of said subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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- 9. A magnetic resonance imager for performing ESREMRI, comprising a first radiation source means for irradiating a sample with a first radiation of a frequency selected to excite an electron spin resonance transition in a paramagnetic species in said sample, a second radiation source means for irradiating said sample with at least one pulse of a second radiation of a frequency selected to excite nuclear spin transitions in selected nuclei in said sample, gradient imposing means for imposing at least one magnetic field gradient across said sample, detection means for detecting magnetic resonance signals from said sample, first control means for controlling said gradient imposing means, and second control means for controlling the operation of said detection means, wherein said first control means imposes across said sample magnetic field read gradients of alternating polarities and said second control means causes said detection means to operate during at least part of the time during which read gradients are imposed.
Specification