Multi-liquid medicament delivery system with reflex valves

• US 5,298,024 A
• Filed: 12/28/1992
• Issued: 03/29/1994
• Est. Priority Date: 12/28/1992
• Status: Expired due to Term

• Current Assignee: Frank Richmond
• Original Assignee: Frank Richmond
• Inventors: Richmond, Frank
• Primary Examiner(s): Rosenbaum, C. Fred
• Assistant Examiner(s): ELGART, VANITHA M
• Application Number:
  US07/997,522
• Time in Patent Office: 456 Days
• Field of Search: 604/194-199, 604/218, 604/231-232, 604/235, 604/236, 604/237, 604/249, 604/82-93, 604/200-205, 604/225, 604/226, 604/244-246, 604/68, 604/70, 604/81 , 604/183, 604/184, 604/139, 604/71, 604/131, 604/149, 604/191, 604/150
• US Class Current: 604/90
• CPC Class Codes: A61M 2005/1787 Syringes for sequential delivery of fluids, e.g. first medicament and then flushing liquid
• CPC Class Codes: A61M 2005/31508 provided on the piston-rod
• CPC Class Codes: A61M 39/02 Access sites
• CPC Class Codes: A61M 5/31595 Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
• CPC Class Codes: A61M 5/31596 comprising means for injection of two or more media, e.g. by mixing

Abstract

A syringe for sequentially injecting a plurality of liquids into an intravenous (IV) infusion component that has a connector fitting includes a syringe vessel having a preferably needleless injection port that is engageable with the connector fitting of the IV component. A syringe plunger is slidably disposed in the syringe vessel, and at least one barrier plunger is slidably disposed in the syringe vessel between the injection port and the syringe plunger. The barrier plunger is formed with a pathway for fluid communication therethrough, and a valve is positioned in the pathway of the barrier plunger to block fluid communication through the pathway. A nipple extends inwardly from the injection port for opening the valve of the barrier plunger when the barrier plunger is urged against the nipple. A first liquid is disposed in the syringe vessel between the barrier plunger and the injection port and a second liquid is disposed in the syringe vessel between the two plungers. The syringe plunger can be advanced against the second liquid toward the injection port, thereby urging the barrier plunger against the first liquid to expel the first liquid through the injection port. As the syringe plunger is advanced further into the vessel, the barrier plunger is urged against the nipple of the injection port to open the valve, thereby establishing a pathway for fluid communication through the channel of the barrier plunger for expelling the second liquid through the injection port.

Claims

1. A multi-liquid medicament delivery system, comprising:

a syringe vessel having a wall and an injection port formed through the wall, the injection port being configured for engaging a needleless IV fitting;

a syringe plunger slidably disposed in the syringe vessel;

a barrier plunger slidably disposed in the syringe vessel between the syringe plunger and the injection port, the barrier plunger including a channel; and

valve means for blocking the channel of the barrier plunger, the valve means having an open configuration, wherein fluid communication through the channel is permitted, and a closed configuration, wherein no fluid communication through the channel is permitted.

2. The system as recited in claim 1, further comprising a first liquid disposed in the syringe vessel between the barrier plunger and the injection port, and a second liquid disposed in the syringe vessel between the syringe plunger and the barrier plunger, for sequential expulsion of the liquids from the syringe vessel.

3. The system as recited in claim 2, wherein the injection port includes a nipple protruding inwardly toward the barrier plunger.

4. The system as recited in claim 3, wherein the valve means is biased to the closed configuration, and the nipple of the injection port is configured for engaging the valve means and moving the valve means to the open configuration.

5. The system as recited in claim 4, wherein the valve means is a valve, and the valve includes a hollow body defining a fluid passageway therethrough, the valve also including a resilient valve disc positioned in the fluid passageway and being biased into a closed configuration, wherein the disc blocks fluid flow through the fluid passageway, the disc being movable to an open configuration wherein fluid flow is permitted through the fluid passageway.

6. The system of claim 5, wherein the valve disc has a center and the valve further includes a support element positioned on the valve for supporting the valve disc at the center of the disc.

7. The system of claim 6, wherein the valve further includes a retainer element positioned in the valve on the opposite side of the disc from the support element, to hold the center of the disc against the support element.

8. The system of claim 7, further comprising an urging member reciprocally disposed in the fluid passageway of the valve on the same side of the disc as the retainer element, the urging member being movable between a first position, wherein the urging member is distanced from the valve disc, and a second position, wherein the urging member contacts the valve disc to move the disc into its open configuration.

9. The system of claim 8, wherein the urging member is moved to its second position by the nipple of the injection port.

10. The system as recited in claim 5, further comprising a handle attached to the syringe plunger.

11. The system as recited in claim 10, wherein the handle can be manipulated to urge the syringe plunger into the second liquid toward the injection port, thereby urging the barrier plunger into the first liquid to expel the first liquid through the injection port.

12. The system as recited in claim 11, wherein the handle can be manipulated to expel substantially all of the first liquid from the injection port and urge the barrier plunger against the nipple of the injection port to open the valve means, thereby establishing a pathway for fluid communication through the channel of the barrier plunger for expelling the second liquid through the injection port, the handle includes at least one stop for abutting the syringe vessel.

13. The system as recited in claim 12, further comprising a third plunger slidably disposed in the syringe vessel between the second liquid and the syringe plunger, and a third liquid disposed in the syringe vessel between the first and third plungers, the third plunger having a channel therethrough and means disposed in the channel for selectively blocking fluid communication through the channel.

14. A syringe for sequentially injecting a plurality of liquids into an intravenous (IV) infusion component having a needleless connector fitting, comprising:

a syringe vessel having an injection port engageable with the connector fitting of the IV component;

a syringe plunger slidably disposed in the syringe vessel;

a barrier plunger slidably disposed in the syringe vessel between the injection port and the syringe plunger, the barrier plunger being formed with a pathway for fluid communication through the barrier plunger;

a valve positioned in the pathway of the barrier plunger to block fluid communication therethrough; and

a nipple extending inwardly from the injection port for opening the valve of the barrier plunger when the barrier plunger is urged against the nipple.

15. The syringe of claim 14, further comprising a first liquid disposed in the syringe vessel between the barrier plunger and the injection port and a second liquid disposed in the syringe vessel between the two plungers.

16. The syringe of claim 15, further comprising a third plunger slidably disposed in the syringe vessel between the second liquid and the syringe plunger, and a third liquid disposed in the syringe vessel between the syringe plunger and the third plunger, the third plunger having a channel formed therethrough and a valve disposed in the channel for selectively blocking fluid communication through the channel of the third plunger.

17. The syringe of claim 16, further comprising a handle attached to the syringe plunger, wherein the handle can be manipulated to urge the syringe plunger against the second liquid toward the injection port, thereby urging the barrier plunger against the first liquid to expel the first liquid through the injection port.

18. The syringe as recited in claim 17, wherein the handle can be manipulated to expel substantially all of the first liquid from the injection port and urge the barrier plunger against the nipple of the injection port to open the valve and thereby establish a pathway for fluid communication through the channel of the barrier plunger for expelling the second liquid through the injection port.

19. A system for holding a plurality of liquids and sequentially expelling the liquids from the system into a needleless connector fitting, comprising:

a syringe vessel having an injection port engageable with the connector fitting, the vessel holding a first liquid and a second liquid;

a barrier plunger slidably disposed in the syringe vessel between the two liquids, the barrier plunger being formed with a pathway for fluid communication through the barrier plunger;

a valve positioned in the pathway of the barrier plunger to block fluid communication therethrough; and

a nipple extending inwardly from the injection port for opening the valve of the barrier plunger when the barrier plunger is urged against the nipple.

20. The system of claim 19, further comprising a syringe plunger slidably disposed in the syringe vessel with the second liquid being disposed between the syringe plunger and the barrier plunger, the syringe plunger having a handle attached thereto for grasping the handle and urging the syringe plunger toward the injection port of the syringe vessel, thereby urging the barrier plunger toward the first liquid to expel the first liquid through the injection port.