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Mass sensor method for measuring analytes in a sample

  • US 5,306,644 A
  • Filed: 04/01/1993
  • Issued: 04/26/1994
  • Est. Priority Date: 09/29/1988
  • Status: Expired due to Fees
First Claim
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1. A measurement system for determining the amount of at least one analyte in a liquid sample suspected of containing such analytes comprising:

  • a plurality of piezoelectric surface transverse wave sample devices comprising a receptor layer attached to the surface thereof, which receptor layer contains receptor molecules which are complementary to the analytes and which device generates data relating to the mass change on the surface of the device arising from contacting the device with the sample;

    at least one piezoelectric surface transverse wave reference device comprising a receptor layer having little or no affinity for the analyte(s) and which generates data as to the interferences arising from contacting the device with the liquid sample; and

    a measurement instrument capable of correlating the data from the sample and reference devices so as to provide data on at least one of the presence and amount of the analytes in the liquid sample.

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