Photometer

• US 5,307,144 A
• Filed: 12/01/1992
• Issued: 04/26/1994
• Est. Priority Date: 12/02/1991
• Status: Expired due to Fees

• Current Assignee: Seikagaku Kogyo Kabushiki Kaisha
• Original Assignee: Seikagaku Kogyo Kabushiki Kaisha
• Inventors: Shigenori, Tanaka, Hiroshi, Tamura
• Primary Examiner(s): Rosenberger, Richard A.
• Assistant Examiner(s): Pham, Hoa Q.
• Application Number:
  US07/984,535
• Time in Patent Office: 511 Days
• Field of Search: 356/244, 356/246, 356/414, 356/432, 356/435, 356/439, 356/440, 356/319, 356/320, 250/576, 250/238, 250/429, 422/101, 422/102, 422/186, 422/109, 422/58, 422/61, 436/165, 436/809
• US Class Current: 356/244
• CPC Class Codes: B01L 3/50851 specially adapted for heating or cooling samples laboratory heating apparatus B01L7/00; incubators C12M
• CPC Class Codes: B01L 3/50853 with covers or lids
• CPC Class Codes: B01L 7/02 Water baths; Sand baths; Air baths
• CPC Class Codes: G01N 2021/0325 Cells for testing reactions, e.g. containing reagents
• CPC Class Codes: G01N 21/031 Multipass arrangements
• CPC Class Codes: G01N 21/0332 with temperature control control of temperature G05D23/00; cryostats F17C3/08
• CPC Class Codes: G01N 21/253 for batch operation, i.e. multisample apparatus analytical automats G01N35/00
• CPC Class Codes: G01N 2201/0446 Multicell plate, sequential
• CPC Class Codes: Y10S 436/809 Multifield plates or multicontainer arrays

Abstract

The present invention intends to generally maintain the microplate having added test samples in wells therein at even temperature for measuring biochemical or biological reaction accompanying changes in absorbance such as enzyme reaction. Monochromatic lights with various wave lengths from a light source 3 are transmitted through the test samples added to a plurality of wells in a microplate 1 to measure absorbance of the test sample. For this end, a metal plate 2 with good heat conductivity is substantially contacted with the bottom of each well in the microplate 1 and a perforated board 7 is disposed with an air space over the microplate 1 at the starting position thereof. Warmed air heated by a heater 17 is blown onto the microplate 1 through the perforated board 7 and is circulated along the metal plate 2 within a chamber 9.

Claims

1. A photometer for transmitting monochromatic light with various wavelengths through test samples in a plurality of wells in a microplate for measuring the absorbance of the test samples,

characterized in comprising a metal plate with good heat conductivity disposed substantially in contact with the bottom surface of each well of said microplate, a board having a plurality of openings therein and disposed with an air space over said microplate at a starting position thereof, air circulation means for enforcedly circulating air, and heating means to heat the air wherein said microplate, said metal plate and said board are disposed in a chamber,

wherein air is blown onto the upper surface of said microplate by way of said board having openings and is circulate along said metal plate with good heat conductivity.

2. A photometer in accordance with claim 1 wherein said metal plate with good heat conductivity is formed with openings at the locations corresponding to the wells in said microplate under which said metal plate is placed.