Externally moveable intracavity probe for MRI imaging and spectroscopy

• US 5,307,814 A
• Filed: 09/17/1991
• Issued: 05/03/1994
• Est. Priority Date: 09/17/1991
• Status: Expired due to Term

• Current Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Original Assignee: Medrad Incorporated (Bayer AG), Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Inventors: Kressel, Herbert Y., Rhinehart, Edward J., Imai, Yutaka, Lenkinski, Robert E., Schnall, Mitchell
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): ZELE, KRISTA MICHELLE
• Application Number:
  US07/760,463
• Time in Patent Office: 959 Days
• Field of Search: 128/653.2, 128/653.5, 128/778, 128/657, 128/772, 128/786, 606/191-194, 606/197, 604/55, 604/96, 604/104
• US Class Current: 600/423
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/4255 Intestines, colon or appendix
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: G01R 33/285 Invasive instruments, e.g. catheters or biopsy needles, specially adapted for tracking, guiding or visualization by NMR
• CPC Class Codes: G01R 33/34084 implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts
• CPC Class Codes: G01R 33/341 comprising surface coils

Abstract

An insertable intracavity probe for use in magnetic resonance imaging of an area of interest in a body cavity particularly the colon, has an elongate shaft with a handle at its proximal end and an inflatable balloon structure at its distal end. The balloon structure has an outer balloon containing a loop-type pickup coil for connection to an interfacing network. The coil is sandwiched between two internal separately inflatable balloons, and when the probe is inserted, the coil can be optimally positioned relative to the area of interest by controlled differential inflation of the balloons. The probe also has an insertable rod-like mandrel for providing twisting orbital-type movement of the balloon structure on the shaft, by rotation of the mandrel, useful to steer the probe along curves or bends in the body cavity when it is being inserted. In a modified form of the probe, the mandrel can be used to rotate the coil and the internal balloons as a unit within the outer balloon for optimal in situ angular positioning of the coil.

Claims

1. An insertable intracavity probe for use in magnetic resonance imaging with an interface network of a region of interest within a cavity of a patient comprising an elongate shaft having a proximal end and a distal end, a handle on the proximal end of the shaft, and a balloon structure on the distal end of the shaft, the balloon structure including an outer balloon, a pick-up coil in the outer balloon, the coil having an electrical lead extending through the shaft for connecting the coil to the interface network, first and second inflatable inner balloons within the outer balloon, the inner balloons being located on first and second sides of the coil, respectively, sandwiching the coil therebetween, and respective inflation tubes for inflating the inner balloons extending through the shaft.

2. The invention as defined in claim 1 including control means for selectively and individually controlling inflation pressure for the respective inner balloons.

3. The invention as defined in claim 2 wherein the control means includes a stopcock on each of said inflation tubes and connector means for attaching the tubes to an inflation source.

4. The invention as defined in claim 1 which includes a stiffener tube extending from the shaft through the balloon structure.

5. The invention as defined in claim 1 which includes a rod-like mandrel for insertion into the elongate shaft from a proximal end of the handle, the mandrel having a length to extend, when inserted substantially from a distal end of the balloon structure out of the proximal end of the handle.

6. The invention as defined in claim 5 wherein the mandrel has a curved distal end portion for providing orbital twisting movement of the balloon structure on the shaft when the mandrel is rotated in the shaft.

7. The invention as defined in claim 6 wherein the mandrel has a proximal end with a mark for indicating an orientation of the curved distal end portion of the mandrel.

8. The invention as defined in claim 7 wherein the mandrel as a knob at the proximal end and said mark is on the knob.

9. The invention as defined in claim 1 wherein the shaft includes identifying means for indicating an orientation of the coil.

10. The invention as defined in claim 9 wherein the identifying means is a longitudinal stripe on the shaft.

11. A insertable intracavity probe for use in magnetic resonance imaging with an interface network of a region of interest within a cavity of a patient comprising an elongate shaft having a proximal end and a distal end, a handle on the proximal end of the shaft, a balloon structure on the distal end of the shaft including therein a pickup coil having a lead extending through the shaft for connection to the interface network and an elongate rod-like mandrel having a curved distal end within the balloon structure, the mandrel being insertable within the shaft from a proximal end of the handle, and being for providing guidance and positioning of the balloon structure during insertion into the cavity.

12. The invention as defined in claim 11 which includes a stiffener tube extending from the shaft through the balloon structure and wherein the mandrel fits in a lumen in the stiffener tube.

13. The invention as defined in claim 12 wherein the stiffener tube is rotatably mounted in distal and proximal bearings in the balloon structure whereby rotation of the mandrel effects rotation of the stiffener tube and coil.

14. The invention as defined in claim 13 wherein the coil is embraced by first and second inflatable inner balloons for providing selective positioning of the coil.

15. The invention as defined in claim 11 wherein the mandrel has a proximal end provided with a knob and a mark for indicating orientation of the mandrel in the shaft.

16. An insertable intracavity probe for use in magnetic resonance imaging with an interface network of a region of interest within a cavity of a patient comprising an elongate shaft having a longitudinal axis, a proximal end and a distal end, a handle on the proximal end of the shaft, a balloon on the distal end of the shaft including therein a pickup coil having a lead extending through the shaft for connection to the interface network, a rotatable stiffener tube extending from the shaft through the balloon, bearing means rotatably mounting the stiffener tube within the balloon, an elongate mandrel extending substantially coaxially through the handle, the shaft and a lumen in the stiffener tube whereby rotation of the mandrel effects rotation of the stiffener tube, the mandrel having a proximal end portion extending outwardly from the handle, and attachment means within the balloon securing the coil to the stiffener tube and mandrel for rotation therewith whereby the coil can be angularly rotated and positioned within the balloon by rotation of said proximal end portion of the mandrel.

17. The invention as defined in claim 16 including first and second inflatable inner balloons within the balloon on the shaft, the inner balloons being located on first and second sides of the coil, respectively, sandwiching the coil therebetween, and respective inflation tubes for inflating the inner balloons extending through the shaft wherein the attachment means also secures the inner balloons to the stiffener tube and mandrel for rotation therewith.

18. The invention as defined in claim 16 wherein the bearing means includes a proximal rotary bearing at a proximal end of the balloon, and a distal rotary bearing at a distal end of the balloon.

19. The invention as defined in claim 16 wherein the mandrel includes indicator means for indicating angular orientation of the coil within the balloon.

20. The invention as defined in claim 19 wherein the mandrel has a cross-sectional shape for indicating the angular orientation of the coil within the balloon.

21. The invention as defined in claim 20 wherein the mandrel has a cruciform cross-section.

22. A method of magnetic resonance imaging of a region of interest within a cavity of a patient including the steps of inserting a pickup probe into said cavity, the probe having a distal end balloon structure including a pickup coil and first and second internal inflatable balloons within said structure embracing the coil on opposite sides of the coil, respectively, positioning the balloon structure proximate said region of interest, providing selective and independent inflation of the internal balloons to influence positioning of the coil within said structure so as to optimally position the coil in relation to said region of interest, and using the coil for said imaging.

23. A method as defined in claim 22 which further includes rotating the coil and inner balloons with said balloon structure to obtain optimal positioning of the coil.

24. In a method of magnetic resonance imaging of a region of interest within a cavity of a patient using a pcikup probe having an elonage shaft with a balloon structure at a distal end thereof including a pickup coil therein an an elongate mandrel having a curved distal end inserted into the shaft and extending into the balloon structure, the improvement which comprises manipulating the balloon structure by rotation of the elongate mandrel about a lengthwise axis of the shaft to assist in, positioning of the probe, and using the pickup coil for said imaging.

25. The method defined in claim 24 wherein the method further comprises providing orbital movement of the balloon structure about the shaft by rotation of the mandrel.

26. A method of magnetic resonance imaging a region of interest within a cavity of a patient including the steps of inserting a pickup probe into said cavity, the probe having a distal end balloon structure including a pickup coil therein, positioning the balloon structure proximate said region of interest, selectively rotating the coil within said balloon structure to optimally position the coil with respect to said region of interest and using the coil for said imaging.

27. A method as defined in claim 26 further including a step of influencing the coil laterally within the balloon structure to obtain optimum positioning of the coil in relation to said region of interest.