Multidimensional imaging using a single point detector for a phase encoded modulated optical carrier

• US 5,309,912 A
• Filed: 11/08/1991
• Issued: 05/10/1994
• Est. Priority Date: 11/08/1991
• Status: Expired due to Term

• Current Assignee: United States Department Of Health And Human Services
• Original Assignee: United States Department Of Health And Human Services
• Inventors: Knuttel, Alexander
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): GILBERT, SAMUEL G
• Application Number:
  US07/789,517
• Time in Patent Office: 914 Days
• Field of Search: 128/653.1, 128/654, 128/655, 356/345, 356/349
• US Class Current: 600/425
• CPC Class Codes: G01N 2021/1759 Jittering, dithering, optical path modulation
• CPC Class Codes: G01N 2021/1765 Method using an image detector and processing of image signal
• CPC Class Codes: G01N 2021/4173 Phase distribution
• CPC Class Codes: G01N 21/4795 spatially resolved investigating of object in scattering medium in vivo A61B
• CPC Class Codes: G01N 2201/067 Electro-optic, magneto-optic, acousto-optic elements

Abstract

Optical imaging of an object utilizes a plurality of amplitude modulated light rays propagating through the object, either sequentially or simultaneously, for detection by a single photodetector. The light rays may propagate geometrically (i.e., directly) or diffusively. Each of the rays is encoded with a different phase to provide sufficient information for decoding the light intensity detected by the photodetector. The rays may be applied simultaneously in an array, in which case different carrier frequencies as well as different phases are applied to the different rays by any of a number of modulators. Alternatively, the rays may be individually applied to the object in a sequence of phase encoded rays. In either case, the single photodetector receives sufficient information to image each of the voxels of interest in the object being imaged. Information may be obtained for different voxels selected for imaging without mechanical scanning.

Claims

1. In an apparatus for imaging attenuation and phase shift characteristics of an object including applying means for applying to a surface of the object a plurality of electromagnetic rays each having a carrier frequency in an optical frequency spectrum, each of said rays modulated by a modulation frequency, and detecting means for detecting the electromagnetic rays after attenuation and phase shifting by each of a plurality of voxels (volume elements of interest),

the improvement wherein said voxels are disposed in an array of n dimensions where n is at least equal to 1 and said detecting means comprises only a single optical detecting cell for detecting electromagnetic radiation resulting at a single point from attenuation and phase shift of said plurality of rays by said plurality of voxels, and

processing means for processing an output signal from said single cell to provide data identifying optical attenuation and phase shift characteristics of each of said voxels thereby to image said plurality of voxels.

2. An improved imaging apparatus in accordance with claim 1 wherein said electromagnetic rays are applied to the object substantially simultaneously in an array of a plurality of rays, and further comprising phase array means for providing a predetermined phase shift to each of said electromagnetic rays thereby to phase encode the electromagnetic rays incident on the surface of the object.

3. An improved imaging apparatus in accordance with claim 2 wherein said phase array means comprise a plurality of optical paths having various different path lengths, thus providing various different phase shifts to said rays.

4. An improved imaging apparatus in accordance with claim 3, wherein said phase array means comprises a plurality of free space optical paths each including means for receiving a respective rays and means establishing a predetermined free space optical path for the respective ray, said means establishing including a corner cube reflector displaced by a predetermined distance from said means for receiving thereby providing a predetermined optical path and a predetermined phase shift to the respective ray prior to incidence of the respective ray on a respective voxel to be imaged thereby.

5. An improved imaging apparatus in accordance with claim 3, wherein said phase array means comprises a plurality of fiber optical paths each optical path including means for receiving a respective ray and a predetermined length of optical fiber between said means for receiving and said surface of said object thereby providing a predetermined optical path and a predetermined phase shift to the respective ray prior to incidence of that ray on a respective voxel to be imaged thereby.

6. An improved imaging apparatus in accordance with claim 2 wherein said phase array means comprises a plurality of condition responsive optical devices for modulating each of said electromagnetic rays and for providing predetermined phase shifts to each of said rays modulated thereby.

7. An improved imaging apparatus in accordance with claim 6 wherein said condition responsive optical devices comprise a plurality of electro-optic means each receiving an unmodulated electromagnetic ray and connected to receive an electrical signal from a source of electrical signals to modulate the ray received thereby at a predetermined frequency and phase to provide said predetermined phase shifts to each of said rays.

8. An improved imaging apparatus in accordance with claim 6 wherein said condition responsive optical devices comprise a plurality of acousto-optic means each receiving an unmodulated electromagnetic ray and connected to receive an electromagnetic signal which is transformed thereby to an acoustic signal to modulate the received ray at a predetermined frequency and phase to provide said predetermined phase shifts to each of said rays.

9. An improved imaging apparatus in accordance with claim 6, wherein said condition responsive optical devices comprise a plurality of opto-optic means each receiving an unmodulated electromagnetic ray and connected to receive an optical signal to modulate an intensity of the ray received thereby at a predetermined frequency and phase to provide said predetermined phase shifts to each of said rays.

10. An improved imaging apparatus in accordance with claim 1, wherein said applying means comprises modulating means for modulating each of said plurality of electromagnetic rays by a respective modulation frequency thereby producing a plurality of electromagnetic rays modulated at respective modulation frequencies, and for applying said plurality of modulated electromagnetic rays to said surface of said object.

11. An improved imaging apparatus in accordance with claim 10, wherein said plurality of electromagnetic rays are applied to the object substantially simultaneously in an array, and wherein said applying means further comprise phase array means for providing a respective predetermined phase shift to each of said modulated electromagnetic rays thereby to phase encode the electromagnetic rays incident on the surface of the object.

12. An improved imaging apparatus in accordance with claim 11 wherein said phase array means comprises a plurality of optical paths having various different path lengths, thus providing various different phase shifts to said rays.

13. An improved imaging apparatus in accordance with claim 10, wherein the modulating frequency applied by said modulating means operates to amplitude modulate a beam intensity of each said electromagnetic ray is less than approximately one percent of the carrier frequency.

14. An improved imaging apparatus in accordance with claim 10, wherein said modulating means includes means for amplitude modulating a beam intensity of each said electromagnetic ray by a different modulation frequency.

15. An improved imaging apparatus in accordance with claim 1, wherein said applying means comprises sequencing means for sequentially applying said plurality of electromagnetic rays to the object.

16. In an apparatus for imaging attenuation and phase shift characteristics of an object including applying means for sequentially applying to a surface of the object a sequence of intensity modulated electromagnetic rays each having a carrier frequency in an optical frequency spectrum, and detecting means for detecting the electromagnetic rays after attenuation and phase shifting by each of a plurality of voxels (volume elements of interest),

the improvement wherein said voxels are disposed in an array of n dimensions where n is at least equal to 1 and said detecting means comprises only a single optical detecting cell for detecting electromagnetic radiation resulting at a single point from attenuation and phase shift of each of said sequence of rays by said plurality of voxels, and

processing means for processing an output signal from said single cell to provide data identifying optical attenuation and phase shift characteristics of each of said voxels thereby to image said plurality of voxels,

wherein said applying means comprises modulating means for modulating each of said sequence of electromagnetic rays, thereby producing a sequence of intensity modulated electromagnetic rays, and for sequentially applying said sequence of modulated electromagnetic rays to said surface of said object.

17. In an apparatus for imaging optical attenuation and phase shift characteristics of an object including applying means for applying to a surface of the object a plurality of electromagnetic rays each having a carrier frequency in an optical frequency spectrum, each of said rays modulated by a modulation frequency, and detecting means for detecting the electromagnetic rays after attenuation and phase shifting by each of a plurality of voxels (volume elements of interest),

the improvement wherein said voxels are disposed in an array of n dimensions where n is at least equal to 1 and said detecting means comprises only a single optical detecting cell for detecting electromagnetic radiation resulting at a single point from attenuation and phase shift of said plurality of rays by said plurality of voxels, and

processing means for processing an output signal from said single cell to provide data identifying optical attenuation and phase shift characteristics of each of said voxels thereby to image said plurality of voxels.