Method for manufacturing an ampule

• US 5,312,577 A
• Filed: 05/08/1992
• Issued: 05/17/1994
• Est. Priority Date: 05/08/1992
• Status: Expired due to Term

• Current Assignee: Bioject Incorporated
• Original Assignee: Bioject Incorporated
• Inventors: Casey, James P. Sr., Ashley, John W., Bartholomew, Victor L., McKinnon, Charles N. Jr., Peterson, Steven F.
• Primary Examiner(s): Silbaugh, Jan H.
• Assistant Examiner(s): Fiorilla, Christopher A.
• Application Number:
  US07/880,249
• Time in Patent Office: 739 Days
• Field of Search: 264/154, 264/161, 264/162, 264/328.1, 425/577, 425/468, 249/149
• US Class Current: 264/154
• CPC Class Codes: A61M 2207/00 Methods of manufacture, assembly or production
• CPC Class Codes: A61M 5/30 Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
• CPC Class Codes: A61M 5/3007 with specially designed jet passages at the injector's distal end
• CPC Class Codes: A61M 5/3134 characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
• CPC Class Codes: B29C 33/304 centering cores
• CPC Class Codes: B29C 39/10 incorporating preformed parts or layers, e.g. casting around inserts or for coating articles coating a surface by casting in general B05D1/30, B29C39/126 takes precedence
• CPC Class Codes: B29C 45/261 having tubular mould cavities
• CPC Class Codes: B29C 45/36 having means for locating or centering cores
• CPC Class Codes: B29C 70/766 on the end part of a tubular article
• CPC Class Codes: B29K 2069/00 Use of PC, i.e. polycarbonates or derivatives thereof, as moulding material
• CPC Class Codes: B29L 2031/7544 Injection needles, syringes

Abstract

A method and mold for making an ampule for a needleless or jet injector device. The tip of a core pin is guided into a clearance hole sufficiently large to prevent the tip from hitting the mold cavity. Plastic is injected into the mold and flows into the space between the core pin tip and the clearance hole forming a vestigial nozzle pilot cylinder around and over the ampule nozzle. The ampule is removed from the mold and the vestigial nozzle pilot cylinder is removed to form a finished ampule. A core pin tip is made of drawn wire or is separately replaceable on the core pin. A nozzle of an ampule is cast in place. An ampule is molded with an enlarged nozzle and a separate orifice is installed in the ampule to provide the desired nozzle opening.

Claims

1. In a method of fabricating a nozzle section of a jet injection ampule having a nozzle opening at a front end of the nozzle section, by thermoplastic injection molding of the type using a mold cavity housing and a core pin, and including the steps of moving the core pin into the mold cavity housing to form a mold cavity and injecting thermoplastic into the mold cavity, the improvement comprising the steps of:

guiding a core pin tip on the core pin at least partially into a clearance hole formed by clearance hole walls in the mold cavity housing, without allowing the core pin tip to hit the clearance hole walls, the clearance hole extending beyond the nozzle section of the molded ampule;

allowing the thermoplastic to flow into the clearance hole and around the core pin tip during said injecting step without allowing the core pin tip to hit the clearance hole walls;

allowing the thermoplastic to at least partially solidify and form a nozzle pilot cylinder within the clearance hole and around the core pin tip, with the core pin tip and nozzle pilot cylinder extending beyond the nozzle section;

removing the nozzle section from the mold cavity housing; and

removing the nozzle pilot cylinder from the nozzle section to expose the nozzle opening.

2. The method of claim 1 wherein the thermoplastic is polycarbonate.

3. The method of claim 1 wherein the core pin tip is drawn wire.

4. The method of claim 1 wherein the core pin tip is tungsten wire.

5. The method of claim 1 wherein the core pin tip is detachable from the core pin for replacement.