Regenerative electrical

• US 5,314,457 A
• Filed: 04/08/1993
• Issued: 05/24/1994
• Est. Priority Date: 04/08/1993
• Status: Expired due to Term

• Current Assignee: Spinal Cord Society
• Original Assignee: Spinal Cord Society
• Inventors: Geisler, Mark S., Jeutter, Dean C.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US08/044,634
• Time in Patent Office: 411 Days
• Field of Search: 607/60, 607/65, 607/116, 607/32, 607/30, 607/115, 128/903
• US Class Current: 607/116
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators
• CPC Class Codes: Y10S 128/903 Radio telemetry

Abstract

A regenerative electrical stimulation device comprising a stimulator portion to be surgically implanted in patients and an external controller portion. The implanted stimulator portion provides electrical stimuli of selected parameters to damaged nerve tissue to stimulate regeneration and/or healing of the damaged nerve tissue. The external controller portion communicates with the implanted stimulator portion to turn the stimulator portion on and off, to change the parameters of the electrical stimuli, to recharge the batteries, and to monitor the status of the batteries. The implanted portion has an antenna coil, a receiver, a programmable control processor, rechargeable batteries, and a passive transmitter. The external controller portion has an antenna coil, a control processor, a transmitter, a receiver for receiving the data passively transmitted by the implantable portion, and a display means.

Claims

1. A nerve regeneration device of the type comprising an external controller portion and an implantable stimulator portion, the stimulator portion to provide electrical stimulus to nerve tissue;

the external controller comprising;

a first antenna coil;

a radio frequency transmitter connected to the antenna coil, the transmitter generating electromagnetic radiation at a selected transmission frequency;

whereby the antenna coil radiates the electromagnetic radiation as a signal;

a first receiver means connected to the first antenna coil to detect electromagnetic radiation reflected back to the first antenna coil, the receiver having means for generating a signal corresponding to the reflected electromagnetic radiation;

a control processor connected to the receiver means, the control processor having means for receiving and responding to said signal;

the stimulator portion comprising;

a second antenna coil that couples with the first antenna coil and absorbs a portion of the electromagnetic radiation;

a sensing means for detecting a specified condition of the stimulator portion, the sensing means providing a condition indicating signal which varies as a function of the condition;

a reflecting means for reflecting a portion of the electromagnetic radiation as a signal back to the first antenna coil;

a switching means for activating and deactivating said reflecting means;

a second control processor connected to the switching means and to the sensing means;

the control processor having means for operating the switching means in accordance with the condition indicating signal, whereby the reflected electromagnetic radiation forms an encoded signal corresponding to the specified condition.

2. The device of claim 1, wherein the signal produced by the first receiving means corresponds to the encoded signal.

3. The device of claim 2, wherein the control processor further comprises means for converting the signal from the first receiver means into a signal corresponding to the condition indicating signal, and wherein the external controller portion further comprises a display means, the display means connected to the first control processor the display means having means for responding to the signal from the first control processor for indicating the condition of the stimulator portion.

4. The device of claim 3, further comprising a full-wave bridge rectifier circuit connected to the tuned circuit whereby the rectifier circuit has a direct current voltage output and said output is connected to the rechargeable battery means, and wherein the transmitter and antenna coils are sized so that the direct current voltage output is sufficient to recharge the battery means.

5. The device of claim 4, wherein the stimulator portion further comprises a second receiving means connected to the second control processor, and wherein the radio frequency transmitter of the external controller portion comprises a modulator, said modulator connected to the first control processor, the first control processor having means for generating commands to the stimulator portion and to operate the modulator whereby the electromagnetic radiation radiated by the first antenna coil is modulated in accordance with said commands, the second receiving means having means for receiving said modulated electromagnetic radiation and means for conveying a signal corresponding to said commands to the second control processor, and wherein the second control processor includes means for responding to said commands.

6. The device of claim 1, wherein the reflecting means comprises a capacitor electrically connected to the second antenna coil forming a tuned circuit and a means for short circuiting said tuned circuit whereby said short circuiting effects the reflection of the electromagnetic radiation as a signal from the second antenna coil to the first antenna coil.

7. The device of claim 1, wherein the stimulator further comprises a battery means for providing power for the stimulator portion and said battery means is rechargeable.

8. A nerve regeneration device of the type comprising an external controller portion and an implantable stimulator portion that provides electrical stimulus to nerve tissue;

the external controller comprising;

a first antenna coil;

a radio frequency transmitter, the transmitter having means for generating a carrier wave, the transmitter including a means for modulating said carrier wave, the radio frequency transmitter connected to the first antenna coil whereby the antenna coil radiates the modulated carrier wave; and

a first control processor which includes a means for encoding commands to produce an encoded signal to be sent to the stimulator portion, the first control processor connected to the modulating means of the radio frequency transmitter for modulating the carrier wave as a function of the encoded signal; and

the stimulator portion comprising;

a second antenna coil;

a capacitor electrically connected to the antenna coil forming a tuned circuit whereby a coupling effect is created between first antenna coil and the second antenna coil when they are in proximity to each other, and whereby the modulating carrier wave is received by the second antenna coil;

a sensing means for detecting a condition of the stimulator portion, the sensing means providing a condition indicating signal which varies as a function of the condition;

a switching means connected to the tuned circuit, the switching means for short circuiting the tuned circuit whereby the carrier wave is reflected back to the first antenna coil;

a receiver means connected to the second antenna coil, the receiver means having means for receiving the modulated carrier wave and for generating an encoded signal corresponding to the encoded signal produced by the first control processor;

a second control processor connected to the receiver means for receiving and decoding the encoded commands from the external controller portion and for responding to said commands;

the control processor further comprising an operating means connected to the switching means for short circuiting the tuned circuit corresponding to the condition indicating signal to be communicated to the external controller portion;

a rechargeable battery means for providing power for the stimulator portion; and

a means for converting radio frequency power absorbed by the second antenna to recharge the battery means.

9. The device of claim 8, wherein the controller portion further comprises a first receiver means connected to the first antenna coil for detecting the carrier wave reflected back to the first antenna coil, the receiver means generating a signal corresponding to the reflected carrier wave.

10. The device of claim 9, wherein the means for converting the radio frequency power absorbed by the second antenna coil is comprised of a full wave bridge rectifier electrically connected to the tuned circuit.

11. The device of claim 10, wherein the condition is the battery temperature.

12. The device of claim 11, wherein the stimulator portion further comprises a second sensing means for monitoring battery voltage and generating a status indicating signal, said means connected to the control processor.

13. The device of claim 11, wherein the stimulator portion further comprising a plurality of electrodes to provide the electrical stimuli, and whereby electrodes have a voltage across them during stimulation and the stimulator portion further comprises a sensing means for monitoring said voltage and generating a third status indicating signal, said means connected to the control processor.

14. The device of claim 13, further comprising a sensing means for monitoring electrical current through said electrodes and for generating a condition indicating signal corresponding to said current, said means connected to the control processor.

15. The device of claim 14, wherein the carrier wave has a frequency between 1.5 and 2.5 MHz.

16. The device of claim 15, wherein the switching means is comprised of a metal-oxide-semiconductor field-effect transistor.

17. The device of claim 16, wherein the second control processor further comprises a storage means for retaining the commands from the external control portion.

18. The device of claim 17, wherein the stimulator portion further comprises switching means connected to the electrodes for controlling a parameter of the electrical stimuli, said means controlled by the second control processor.

19. The device of claim 18, wherein the electrical stimuli have a polarity and the parameter controlled by the switching means is the polarity of the electrical stimuli.

20. The device of claim 18, wherein the electrical stimuli have an amplitude and the switching means is for controlling said amplitude.

21. The device of claim 18, wherein the electrical stimuli have a frequency and the switching means is for controlling said frequency.

22. The device of claim 18, wherein the electrical stimuli have a pulse width and the analog switching means is for controlling said pulse width.