Artificial bone connection prosthesis

• US 5,314,478 A
• Filed: 04/26/1991
• Issued: 05/24/1994
• Est. Priority Date: 03/29/1991
• Status: Expired due to Term

• Current Assignee: Kabushiki Kaisha Biomaterial Universe Corporation of Japan, Kyocera Corporation
• Original Assignee: Kabushiki Kaisha Biomaterial Universe Corporation of Japan, Kyocera Corporation
• Inventors: Ikada, Yoshito, Gen, Shokyu, Oka, Masanori, Okimatsu, Hideaki
• Primary Examiner(s): Green, Randall L.
• Assistant Examiner(s): Nguyen, Dinh X.
• Application Number:
  US07/692,202
• Time in Patent Office: 1,124 Days
• Field of Search: 623/17, 623/18, 623/16, 623/13, 623/19, 623/20, 623/21, 623/22, 623/23, 623/11, 424/422, 424/423
• US Class Current: 623/14.12
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/30756 Cartilage endoprostheses A61F2/3603 takes precedence
• CPC Class Codes: A61F 2/30965 Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
• CPC Class Codes: A61F 2/3603 implanted without ablation of the whole natural femoral head endoprosthetic cartilage A61F2/30756
• CPC Class Codes: A61F 2/44 for the spine, e.g. vertebrae, spinal discs
• CPC Class Codes: A61F 2/442 Intervertebral or spinal discs, e.g. resilient non-disc-shaped intervertebral inflatable pockets A61F2/441; non-disc-shaped intervertebral fusion implants A61F2/4455
• CPC Class Codes: A61F 2002/30113 circular
• CPC Class Codes: A61F 2002/30125 elliptical or oval
• CPC Class Codes: A61F 2002/30133 kidney-shaped or bean-shaped
• CPC Class Codes: A61F 2002/30153 rectangular
• CPC Class Codes: A61F 2002/30154 square
• CPC Class Codes: A61F 2002/30156 triangular
• CPC Class Codes: A61F 2002/30224 cylindrical
• CPC Class Codes: A61F 2002/30261 parallelepipedal
• CPC Class Codes: A61F 2002/30263 cubical
• CPC Class Codes: A61F 2002/3028 polyhedral different from parallelepipedal and pyramidal
• CPC Class Codes: A61F 2002/30563 having elastic means or damping means, different from springs, e.g. including an elastomeric core or shock absorbers
• CPC Class Codes: A61F 2002/30673 Lubricating means, e.g. synovial pocket
• CPC Class Codes: A61F 2002/30915 made of a stack of bonded perforated sheets, grids or wire meshes
• CPC Class Codes: A61F 2002/30971 Laminates, i.e. layered products
• CPC Class Codes: A61F 2230/0006 : circular
• CPC Class Codes: A61F 2230/0008 : elliptical or oval
• CPC Class Codes: A61F 2230/0015 : Kidney-shaped, e.g. bean-shaped
• CPC Class Codes: A61F 2230/0019 : rectangular
• CPC Class Codes: A61F 2230/0021 : square
• CPC Class Codes: A61F 2230/0023 : triangular
• CPC Class Codes: A61F 2230/0063 : Three-dimensional shapes
• CPC Class Codes: A61F 2230/0069 : cylindrical
• CPC Class Codes: A61F 2230/0082 : parallelepipedal
• CPC Class Codes: A61F 2230/0084 : cubical
• CPC Class Codes: A61F 2310/00023 : Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00203 : containing alumina or aluminium oxide
• CPC Class Codes: A61L 27/16 : obtained by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 27/52 : Hydrogels or hydrocolloids
• CPC Class Codes: C08L 29/04 : Polyvinyl alcohol; Partially hydrolysed homopolymers or copolymers of esters of unsaturated alcohols with saturated carboxylic acids

Abstract

A prosthesis used for a damaged bone, an artificial articular cartilage or an artificial intervertebral disc being characterized in that the prosthesis is a composite body comprising polyvinyl alcohol hydrogel and ceramic or metallic porous body. With this prosthesis, PVA hydrogel enhances lubrication and shock absorbing functions, and the porous body allows the ingrowth and ossification of the bone tissue of a living body therein to affinitively connect said hydrogel to the bones of the living body.

Claims

1. A prosthesis used for replacing damaged articular bone portions having bone tissue grown thereon and damaged articular cartilage of a living body, the prosthesis comprising:

polyvinyl alcohol hydrogel and a porous body, wherein the hydrogel is carried into said porous body via infiltration and fixation thereby forming a resulting porous body such that said porous body is shaped in the form of said bone portions or articular cartilage it replaces, and wherein the resulting porous body is positioned at and brought into contact with the articular bone portions so that the bone tissue is allowed to grow into and ossify within said resulting porous body to connect said hydrogel to the bone portions of the living body.

2. A prosthesis according to claim 1 wherein said porous body is selected from the group consisting of ceramic and metallic mesh.

3. A prosthesis according to claim 1, wherein said polyvinyl alcohol hydrogel has a water content of 10 to 60 weight %.

4. A prosthesis used for replacing damaged articular bone portions having bone tissue grown thereon and damaged articular cartilage of a living body, the prosthesis comprising:

polyvinyl alcohol hydrogel and a porous body, wherein said polyvinyl alcohol has a polymerization rate of at least 1700 and a saponification rate of at least 99.5 mol % is carried into said porous body via infiltration and fixation thereby forming a resulting porous body, and wherein the resulting porous body is positioned at and brought into contact with the articular bone portions so that the bone tissue is allowed to grow into and ossify within said resulting porous body to connect said hydrogel to the bone portions of the living body.

5. A prosthesis used for replacing damaged articular bone portions having bone tissue grown thereon and damaged articular cartilage of a living body, the prosthesis comprising:

polyvinyl alcohol hydrogel and a porous body of titanium mesh, wherein the hydrogel is carried into said porous body via infiltration and fixation thereby forming a resulting porous body, and wherein the resulting porous body is positioned at and brought into contact with the articular bone portions so that the bone tissue is allowed to grow into and ossify within said resulting porous body to connect said hydrogel to the bone portions of the living body.

6. A prosthesis according to claim 5, wherein the porous body is alumina.

7. A prosthesis device for replacing bone or articular cartilage, the device comprising:

a porous body; and

polyvinyl alcohol hydrogel, wherein said hydrogel is fixed within the porous body such that said porous body is shaped in the form of said bone or articular cartilage it replaces.

8. The prosthetic device according to claim 7, wherein the porous body is selected from the group consisting of ceramic and metallic mesh.

9. The prosthetic device according to claim 8, wherein the ceramic porous body is alumina having a porosity of 20% to 80%.

10. The prosthetic device according to claim 7, wherein the porous body is titanium mesh.

11. A prosthetic device for replacing damaged bone and articular cartilage, the device comprising:

a porous body;

polyvinyl alcohol hydrogel having a water content of approximately 10 to 60 weight %;

said porous body being selected from the group consisting of ceramic and metallic mesh;

said hydrogel being fixed within the porous body when the bone and articular cartilage are replaced; and

said porous body having the hydrogel fixed therein being shaped in the form of the bone and the articular cartilage replaced.

12. A prosthetic device according to claim 11, wherein the ceramic porous body is alumina.

13. A prosthetic device according to claim 11, wherein the metallic mesh porous body is titanium.