Erythrocyte sedimentation rate measuring apparatus

• US 5,316,729 A
• Filed: 11/27/1992
• Issued: 05/31/1994
• Est. Priority Date: 05/29/1991
• Status: Expired due to Fees

• Current Assignee: Dietmar Holst, Helmut Orth, Joachim Horrer
• Original Assignee: Dietmar Holst, Helmut Orth, Joachim Horrer
• Inventors: Orth, Helmut, Horrer, Joachim, Holst, Dietmar
• Primary Examiner(s): Housel, James C.
• Assistant Examiner(s): BHAT, NINA NMN
• Application Number:
  US07/982,313
• Time in Patent Office: 550 Days
• Field of Search: 422/73, 422/82.05, 422/101, 73/864.01, 73/61.63, 73/61.65, 73/61.66, 73/61.69, 436/70
• US Class Current: 422/73
• CPC Class Codes: G01N 15/05 in blood
• CPC Class Codes: G01N 2021/5969 Scanning of a tube, a cuvette, a volume of sample
• CPC Class Codes: G01N 2201/0415 Carrusel, sequential

Abstract

An apparatus for measuring the erythrocyte sedimentation rate comprising a measuring head having at least light barrier, which can be moved along a test cell containing a blood sample. The output signals of light detectors (52, 54, 60) of the light barriers are fed to an evaluating processor (74), which continuously compares the profiles of the optical density obtained at different measuring times with various reference curves having a known final value of the position of the interphase between the serum and the blood cake.

Claims

1. An apparatus for measuring erythrocyte sedimentation rate, comprising test cell support means (18, 20, 24, 26) adapted to position at least one test cell (22) in parallel orientation with respect to the vertical direction, comprising a measuring head (36) measuring the optical density of blood and including at least one light barrier (48, 52), comprising head drive means (34, 40) for providing relative movement between the test cell support means and the measuring head in a direction parallel to the positioning direction of the test cells (22), a position sensor (42, 76) providing a position signal corresponding to the relative position of said at least one test cell (22) and measuring head (36), and an evaluating processor (74) which receives the output signals of the measuring head (36) as well as the position signal and continuously stores (84) the output signals of the measuring head (36) and the associated position signals and compares the stored position signals with at least one reference curve (6, 90;

94-100) and from this comparison extrapolates a presumable final value of the position of the interphase defined between the serum and the blood cake and also determines the sedimentation rate.

2. The measuring apparatus in accordance with claim 1, wherein the evaluating processor (74) compares the stored position signals with a plurality of different reference curves (86, 90;

94-100) and determines the final value of the interphase and sedimentation rate on the basis of the reference curve giving the best fit.

3. The measuring apparatus in accordance with claim 1 wherein the evaluating processor (74) furthermore calculates further characteristic data from the stored signals, including the starting point, the end point and the slope of linear portions of the sedimentation curve representing the change in time of the position of the interphase.

4. The measuring apparatus in accordance with claim 1, wherein the measuring head (36) comprises at least one further light barrier (50, 54), having an operating wavelength that is absorbed by the blood sample more strongly or more weakly than the operating wave length of the first light barrier (48, 50) and the evaluating processor (74) processes the measuring signals obtained from the further light barrier (50, 54) in the same way as the signals obtained from the first light barrier (48, 52).

5. The measuring apparatus as in claim 1, wherein each reference curve comprises a set of reference profiles of the optical density (94-100) covering the vertical extension of the test call.

6. The measuring apparatus as in claim 1, wherein among the light barriers there is at least one (48, 52;

50,

     54) which is a transmission light barrier, the axis of which intersects the axis of the test cell.

7. The measuring apparatus as in claim 1, wherein the measuring head (36) comprises at least one reflection type light barrier (58, 60) and the evaluating processor (74) evaluates the measuring signals obtained therefrom in view of recognizing a bar code carried by the test cell (22).

8. The measuring apparatus in accordance with claim 7, wherein the test cell support means (18, 24, 26) comprises a plurality of receptacles (22) adapted to receive a test cell (22), and support drive means (14, 16) provided to intermittently move the test cell support means by a distance corresponding to the distance between two successive receptacles.