Method and apparatus for determining chemical states of living animal or human tissue using nuclear magnetic resonance
First Claim
1. Method for determining chemical states of living animal or human tissue using nuclear magnetic resonance with a homogeneous constant magnetic field, the tissue being measured by means of a nuclear magnetic resonance measurement and the measured values obtained then being evaluated by comparison with measured values from reference measurements on comparable tissue to assess whether the chemical state of the tissue corresponds to a chemical normal state or to a deviating abnormal end state, wherein the measured values obtained are compared with such a series of reference measurements which also contain detectable characteristic transition states between the chemical normal state and the abnormal end state, and wherein the chemical transition state of the measured tissue sample is determined from the comparison.
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Abstract
In a method for determining chemical states of living animal or human tissue using nuclear magnetic resonance with a homogeneous constant magnetic field, the tissue is measured by means of a high-resolution nuclear magnetic resonance measurement and the measured values obtained are then evaluated by comparison with measured values from resonance measurements on comparable tissue to determine whether the chemical state of the tissue corresponds to a chemical normal state or to a deviating abnormal state. In order to enable a determination of chemical intermediate states to be made, it is proposed to compare the measured values obtained with such a series of reference measurements which also contain the detectable characteristic transition states between the chemical normal state and the abnormal end state and that the chemical transition state of the measured tissue sample is determined from the comparison.
32 Citations
25 Claims
- 1. Method for determining chemical states of living animal or human tissue using nuclear magnetic resonance with a homogeneous constant magnetic field, the tissue being measured by means of a nuclear magnetic resonance measurement and the measured values obtained then being evaluated by comparison with measured values from reference measurements on comparable tissue to assess whether the chemical state of the tissue corresponds to a chemical normal state or to a deviating abnormal end state, wherein the measured values obtained are compared with such a series of reference measurements which also contain detectable characteristic transition states between the chemical normal state and the abnormal end state, and wherein the chemical transition state of the measured tissue sample is determined from the comparison.
- 20. Apparatus for determining chemical states of living animal or human tissue using nuclear magnetic resonance, comprising a nuclear magnetic resonance spectrometer (12) for carrying out a nuclear magnetic resonance measurement on the tissue, computer means (16) for determining measured values for the nuclear magnetic resonance measurement on the tissue, means (24) for storing reference values of measurements on comparable tissue, means for comparing the measured values for actual measurement and reference measurement, and a computation means (22) connected to said means for comparing for making an assignment of the actual measurement to a chemical transition state based on a comparison of the measured values wherein the means (24) for storing reference values consist of a database which contains such a series of reference values for reference measurements which also comprise detectable characteristic transition states between the chemical normal state and the chemically abnormal end state.
Specification