Hypodermic syringe for lyophilized medicament

• US 5,320,603 A
• Filed: 08/20/1992
• Issued: 06/14/1994
• Est. Priority Date: 08/21/1991
• Status: Expired due to Term

• Current Assignee: Arzneimittel GmbH Apotheker Vetter & Co. Ravensburg
• Original Assignee: Arzneimitel GmbH Apotheker Vetter & Company
• Inventors: Vetter, Helmut, Geprags, Peter
• Primary Examiner(s): Yasko, John D.
• Assistant Examiner(s): Wilkens, Frank
• Application Number:
  US07/932,989
• Time in Patent Office: 663 Days
• Field of Search: 604/187, 604/218, 604/191, 604/192, 604/232, 604/82, 604/89-92, 604/407, 604/405, 604/416, 604/199, 604/111, 604/239-243, 215/354, 215/356
• US Class Current: 604/82
• CPC Class Codes: A61M 2005/3104 Caps for syringes without needle
• CPC Class Codes: A61M 2005/3106 Plugs for syringes without needle
• CPC Class Codes: A61M 2005/3118 via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
• CPC Class Codes: A61M 2005/3123 having air entrapping or venting means, e.g. purging channels in pistons
• CPC Class Codes: A61M 2005/3139 Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
• CPC Class Codes: A61M 5/284 comprising means for injection of two or more media, e.g. by mixing
• CPC Class Codes: A61M 5/3134 characterised by constructional features of the distal end, i.e. end closest to the tip of the needle cannula
• CPC Class Codes: A61M 5/34 Constructions for connecting the needle , e.g. to syringe nozzle or needle hub connecting catheter tubes to hubs A61M25/0014
• CPC Class Codes: B65D 51/241 provided with freeze-drying means

Abstract

A hypodermic syringe has a tubular body extending along and centered on an axis and having at an axial front end a small-diameter collar formed with a front radially outwardly open seat and, axially spaced backward therefrom, a rear radially outwardly open seat. An end piece provided with a deformable plug fittable sealingly in the collar is adapted to receive a needle. Mounting fingers extending axially back from the end piece have rear ends that engage in a front position of the end piece in the front seat and in a rear position of the end piece in the rear seat. The fingers are of such an axial length that the plug is fitted snugly into the collar in the rear position but is not snugly fitted in the collar in the front position. When the end piece is in the front position a medicament in the body can be lyophilized and when in the rear position the syringe is plugged.

Claims

1. A hypodermic syringe comprising:

a tubular body extending along and centered on an axis and having at an axial front end a small-diameter collar formed with a front radially outwardly open groove and, axially spaced backward therefrom on the collar, a rear radially outwardly open groove;

an end piece on the front end of the body;

a deformable plug fixed on the end piece, fittable sealingly in the collar and adapted to receive a needle;

mounting formations extending axially back from the end piece and engageable in a front position of the end piece radially inward into the front groove and in a rear position of the end piece radially inward into the rear groove, the formations being of such an axial length that

the plug is fitted snugly into the collar in the rear position and blocks flow out of the body through the front end but

is not snugly fitted in the collar in the front position and forms therewith an annular gap permitting flow out of the body through the front end; and

a piston axially displaceable in the body.

2. The hypodermic syringe defined in claim 1 wherein the formations include a radially inwardly projecting but elastically outwardly deflectable ridge formed on a rear end of the formations.

3. The hypodermic syringe defined in claim 2 wherein the formations are axially rearwardly extending fingers having rear ends forming the ridge and separated by notches that are radially throughgoing and axially rearwardly open.

4. The hypodermic syringe defined in claim 1 wherein the end piece has a rearwardly projecting collar forming a rearwardly tapering frustoconical seat, the plug having a front end fitting complementarily in the tapering seat of the end piece.

5. The hypodermic syringe defined in claim 1 wherein the plug has a rear end formed with

a radially outwardly projecting annular bulge,

a frustoconical and rearwardly tapering intermediate surface extending from immediately forward of the bulge, and

a cylindrical portion immediately forward of the frustoconical surface and of a diameter slightly greater than an inside diameter of the collar.

6. The hypodermic syringe defined in claim 1 wherein the end piece is formed with a forwardly projecting and axially centered tubular extension and with an axially throughgoing passage, the plug having a forward extension fitting complementarily in the end-piece extension, the syringe further comprising

a tip cap fitted over the end-piece extension and blocking a front end of the passage.

7. The hypodermic syringe defined in claim 1, further comprising

a protector ring axially slidable on the end piece between a front position mounted thereon forward of the formations and a rear position engaged around the formations and holding same in the rear position of the end piece in the rear groove against radial outward deflection therefrom.

8. The hypodermic syringe defined in claim 7 wherein the end piece and the protector ring are formed with a ridge and groove that radially interfit in the front position of the ring.

9. The hypodermic syringe defined in claim 7 wherein the protector ring is unitarily formed with a protector cap and is connected to it via a weakened-line region permitting the cap to be snapped off the ring.

10. The hypodermic syringe defined in claim 9 wherein the end piece is formed with a forwardly projecting and axially centered tubular extension, the plug having a forward extension fitting complementarily in the end-piece extension, the syringe further comprising

a tip cap fitted over the end-piece extension and blocking a front end of the passage, the protector cap being formed with a central observation hole aligned with the tip cap but of too small a size for the tip cap to fit through, the protector cap having a front wall sitting on a front face of the tip cap in the rear position of the protector ring.