Method for alleviating and diagnosing symptoms of heart block

• US 5,320,642 A
• Filed: 01/22/1992
• Issued: 06/14/1994
• Est. Priority Date: 06/01/1990
• Status: Expired due to Fees

• Current Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Original Assignee: The Board of Regents of the University of Colorado (University of Colorado System)
• Inventors: Scherlag, Benjamin J.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US07/823,500
• Time in Patent Office: 874 Days
• Field of Search: 128/419 PG
• US Class Current: 607/9
• CPC Class Codes: A61N 1/365 controlled by a physiological parameter, e.g. heart potential evoked response A61N1/371
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

A method for alleviating and diagnosing syndromes of heart block wherein a stimulus is continuously or intermittently delivered via a single electrode catheter at a site in a heart in close proximity to the A-V junction in the heart. The subthreshold stimuli were sufficient to cause impulses in the atrium to pass through the damaged His bundle to the ventricle and the stimuli were set at a level below a level required to excite the heart tissue. The delivery of the stimuli alleviates the symptoms of heart block. In one application, the delivery of the stimuli is used for diagnosing heart block when delivery of the stimuli induces the symptoms of heart block in the patient with partial or covert conduction disease.

Claims

1. A method for alleviating the symptoms of heart block comprising:

generating a subthreshold stimuli below a level required to excite the heart tissue; and

delivering the subthreshold stimuli to the heart for alleviating heart block, the stimuli being sufficient to cause impulses in the atrium to pass to the ventricle and the stimuli being below a level required to excite the heart tissue.

2. The method of claim 1 wherein the step of delivering the subthreshold stimuli is further defined as delivering the subthreshold stimuli.

3. The method of claim 1 wherein the step of delivering the stimuli further comprises:

connecting one end of an electrode catheter to the heart and connecting the opposite end of the electrode catheter for receiving the subthreshold stimuli; and

conducting the subthreshold stimuli through the electrode catheter and delivering the stimuli to the heart via the connection of the one end of the electrode catheter to the heart.

4. The method of claim 1 wherein the stimuli is a DC current having an amplitude sufficient to cause impulses in the atrium to pass to the ventricle and the amplitude being below a level required to excite the heart tissue.

5. The method of claim 1 wherein the stimuli is a train of pulses with each pulse having an amplitude sufficient to cause impulses in the atrium to pass to the ventricle and the amplitude being below a level required to excite the heart tissue.

6. The method of claim 1 wherein the step of delivering the subthreshold stimuli as further defined as delivering the subthreshold stimuli intermittently.