Laser pulse format for penetrating an absorbing fluid

• US 5,321,715 A
• Filed: 05/04/1993
• Issued: 06/14/1994
• Est. Priority Date: 05/04/1993
• Status: Expired due to Term

• Current Assignee: Lumenis Limited (Boston Scientific Corporation)
• Original Assignee: Coherent Inc (Coherent Corp.)
• Inventors: Trost, David
• Primary Examiner(s): Scott, Jr., Leon
• Application Number:
  US08/057,125
• Time in Patent Office: 406 Days
• Field of Search: 372/39, 372/6, 372/25, 372/69, 372/78, 128/303.1
• US Class Current: 372/69
• CPC Class Codes: A61B 18/201 with beam delivery through a hollow tube, e.g. forming an articulated arm through a flexible conduit A61B18/22; Hand-pieces therefor
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2017/00154 pulsed
• CPC Class Codes: A61B 2017/00176 Two pulses, e.g. second pulse having an effect different from the first one

Abstract

A pulse format for a laser system is disclosed for maximizing the energy delivered to a target immersed in an absorbing liquid. A first pulse is generated having an energy sufficient to initiate the formation of a vapor bubble in the liquid medium adjacent the end of the delivery device. A second, high energy pulse is generated after the vapor bubble initiated by the first pulse has expanded an amount sufficient to displace the liquid between the delivery device and the target. In this manner, the second pulse is delivered directly to the target and little energy is lost to the liquid medium.

Claims

1. A method of irradiating a target with laser radiation, wherein said radiation is delivered to the target by a guide having a delivery end, and wherein the delivery end is spaced from the target, and wherein the space between the delivery end of the guide and the target is occupied with a liquid medium, and wherein the laser radiation has a wavelength which is absorbed in the liquid medium, said method comprising the steps of:

generating a first laser pulse having sufficient energy to form a vapor bubble in the liquid medium at the delivery end of the guide; and

generating a second laser pulse a predetermined time after the first laser pulse, said predetermined time being selected to allow the vapor bubble to expand an amount sufficient to displace a substantial portion of the liquid medium from the space between the delivery end of the guide and the target so that said second laser pulse may be delivered to the target through the vapor bubble thereby minimizing the laser radiation absorbed by the liquid medium and maximizing the laser radiation reaching the target.

2. A method as recited in claim 3 wherein said steps of generating first and second pulses are sequentially repeated.

3. A method as recited in claim 1 wherein the energy of the first pulse exceeds an amount given by

4. A method as recited in claim 1 wherein the energy of the second pulse is at least an order of magnitude greater than the energy of the first pulse.

5. A method as recited in claim 1 wherein the first pulse is shorter than the second pulse.

6. A method as recited in claim 1 wherein the duration of the first pulse is less than 100 microseconds.

7. A method as recited in claim 1 wherein the duration of the first pulse is less than 30 microseconds.

8. A method as recited in claim 1 wherein the time period between the end of the first pulse and the beginning of the second pulse is at least 50 microseconds.

9. A method as recited in claim 1 wherein the time period between the end of the first pulse and the beginning of the second pulse is between 100 and 200 microseconds.

10. A laser system for irradiating a target with a laser beam, said target being immersed in a liquid medium, said system comprising:

a gain medium generating an output wavelength which is absorbed by the liquid medium;

means for exciting the gain medium to generate a laser beam;

means for guiding the laser beam from the gain medium to the target, said guide means having a delivery end positioned close to but spaced from the target; and

means for controlling the excitation means, said control means functioning to cause a first laser pulse to be generated having an energy sufficient to form a vapor bubble in the liquid medium at the delivery end of the guide means and wherein said control means further functions to cause a second laser pulse to be generated a predetermined time after the first laser pulse, said predetermined time being selected to allow the vapor bubble to expand an amount sufficient to displace a substantial portion of the liquid medium from the space between the delivery end of the guide means and the target so that said second laser pulse may be delivered to the target through the vapor bubble thereby minimizing the laser radiation absorbed by the liquid medium and maximizing the laser radiation reaching the target.

11. A system as recited in claim 10 wherein the energy of the first pulse exceeds an amount given by

12. A system as recited in claim 10 wherein the energy of the second pulse is at least an order of magnitude greater than the energy of the first pulse.

13. A system as recited in claim 10 wherein the first pulse is shorter than the second pulse.

14. A system as recited in claim 10 wherein the duration of the first pulse is less than 100 microseconds.

15. A system as recited in claim 10 wherein the duration of the first pulse is less than 30 microseconds.

16. A system as recited in claim 10 wherein the time period between the end of the first pulse and the beginning of the second pulse is at least 50 microseconds.

17. A system as recited in claim 10 wherein the time period between the end of the first pulse and the beginning of the second pulse is between 100 and 200 microseconds.

18. A system as recited in claim 10 wherein said control means functions to generate a sequence of first and second pulses.

19. A system as recited in claim 10 wherein said gain medium is a rare earth doped crystal.

20. A system as recited in claim 10 wherein said gain medium is a material selected from the group consisting of Nd:

YAG, Nd;

YLF, Nd;

YAP, Nd;

YALO, Ho;

YAG, Ho;

YSGG, Ho;

YLF and Er;

YAG.

21. A system as recited in claim 10 wherein said gain medium is carbon dioxide.

22. A system as recited in claim 10 wherein said means for guiding the light is an optical fiber.

23. A medical laser system for treating tissue with a laser beam, said tissue being immersed in a liquid medium formed primarily of water, said system comprising:

a solid state gain medium generating an output wavelength between 1.0 and 3.0 microns;

a flashlamp for exciting the gain medium to generate a laser beam;

an optical fiber for guiding the laser beam from the gain medium to the tissue, said fiber having a delivery end positioned close to but spaced from the tissue to be treated; and

means for controlling the flashlamp and functioning to sequentially generate a series of first and second laser pulses, wherein each said first laser pulse has an energy sufficient to form a vapor bubble in the liquid medium at the delivery end of the fiber and wherein each said second laser pulse is generated a predetermined time after the first laser pulse, said predetermined time being selected to allow the vapor bubble created by the first laser pulse to expand an amount sufficient to displace a substantial portion of the liquid medium from the space between the delivery end of the fiber and the tissue so that said second laser pulse may be delivered to the tissue through the vapor bubble thereby minimizing the laser radiation absorbed by the liquid medium and maximizing the laser radiation reaching the target.

24. A system as recited in claim 23 wherein the duration of the first pulse is less than 100 microseconds.

25. A system as recited in claim 24 wherein the time period between the end of the first pulse and the beginning of the second pulse is between 100 and 200 microseconds.

26. A system as recited in claim 24 wherein the time period between the end of the first pulse and the beginning of the second pulse is at least 50 microseconds.

27. A system as recited in claim 26 wherein gain medium is a material selected from the consisting of Nd:

YAG, Nd;

YLF, Nd;

YAP, Nd;

YALO, Ho;

YAG, Ho;

YSGG, Ho;

YLF and Er;

YAG.

28. A system as recited in claim 27 wherein the duration of the second pulse is at least 200 microseconds.

29. A method of irradiating a target with laser radiation, wherein said radiation is delivered to the target by a guide having a delivery end, and wherein the delivery end is spaced from the target, and wherein the space between the delivery end of the guide and the target is occupied with a liquid medium, and wherein the laser radiation has a wavelength which is absorbed in the liquid medium, said method comprising the steps of:

generating a first laser output having sufficient energy to form a vapor bubble in the liquid medium at the delivery end of the guide;

allowing the vapor bubble to expand an amount sufficient to displace a substantial portion of the liquid medium from the space between the delivery end of the guide and the target; and

thereafter generating a second laser output, said second laser output being delivered to the target through the vapor bubble thereby minimizing the laser radiation absorbed by the liquid medium and maximizing the laser radiation reaching the target.

30. A method as recited in claim 29 wherein the energy of the first output exceeds an amount given by

31. A method as recited in claim 29 wherein the energy of the second laser output is at least an order of magnitude greater than the energy of the first output.

32. A method as recited in claim 29 wherein the first and second laser outputs are in the form of pulses and wherein the first pulse is shorter than the second pulse.

33. A method as recited in claim 32 wherein the duration of the first pulse is less than 100 microseconds.

34. A method as recited in claim 32 wherein the duration of the first pulse is less than 30 microseconds.

35. A method as recited in claim 32 wherein the time period between the end of the first pulse and the beginning of the second pulse is at least 50 microseconds.

36. A method as recited in claim 32 wherein the time period between the end of the first pulse and the beginning of the second pulse is between 100 and 200 microseconds.

37. A method as recited in claim 29 wherein said steps of generating first and second outputs are sequentially repeated.