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Peptide production

  • US 5,322,775 A
  • Filed: 11/22/1991
  • Issued: 06/21/1994
  • Est. Priority Date: 06/30/1986
  • Status: Expired due to Term
First Claim
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1. A method of producing a proteinaceous compound, the method comprising the steps of(a) producing milk in a female transgenic, non-human placental mammal, said mammal containing a transgene construct in its somatic and germ cells, said construct comprising(i) a DNA sequence encoding a polypeptide chain of said proteinaceous compound;

  • and(ii) a β

    -lactoglobulin promoter operatively linked to said DNA sequence encoding said polypeptide chain;

    said transgene construct being integrated in such a way that said DNA sequence encoding said polypeptide chain is expressed in the mammary gland of said female mammal and said polypeptide is present in said milk; and

    (b) collecting the milk produced in step (a).

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