Antimicrobial medical devices

• US 5,324,275 A
• Filed: 10/02/1992
• Issued: 06/28/1994
• Est. Priority Date: 10/02/1992
• Status: Expired due to Fees

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Raad, Issam I., Zermeno, Alfonso, Bodey, Gerald P.
• Primary Examiner(s): KRUTER, JEROME
• Application Number:
  US07/956,642
• Time in Patent Office: 634 Days
• Field of Search: 604/20, 604/21, 604/114, 604/265
• US Class Current: 604/265
• CPC Class Codes: A61M 25/0017 specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
• CPC Class Codes: A61N 1/40 Applying electric fields by inductive or capacitive coupling microwave apparatus A61N5/00; Applying radio-frequency signals

Abstract

A catheter assembly is described which comprises a catheter tube, an exterior portion of which is circumferentially surrounded by at least two parallel elongated helical conductive elements which may be operably connected to a first power source to create a first open circuit to induce an antimicrobial effect in the area proximate the exterior conductive elements through oligodynamic activity. The catheter assembly further comprises a hub at its proximal end having a cap containing a second power source. At least two internal conductive elements are disposed along the internal length of the hub and are operably connected to the second power source upon closure of the hub with the cap to create a second open circuit which creates an antimicrobial effect proximate the hub through oligodynamic activity.

Claims

1. A catheter assembly comprising:

(a) a catheter tube having a proximal end and a distal end to transmit fluid therethrough;

(b) a hub at the proximal end of said catheter tube to permit fluid flow through said catheter tube;

(c) at least two elongated external conductive elements fixedly disposed to be in a substantially parallel spaced relation to each other along their entire lengths and to helically surround the exterior circumference of a central portion of said catheter tube, said elements forming portions of an open circuit means upon application of power to said elements, said open circuit means inducing an antimicrobial effect through oligodynamic activity.

2. The catheter assembly of claim 1 wherein said elongated external conductive elements may be operably connected toward their proximal ends to power to form said open circuit means.

3. The catheter assembly of claim 2, wherein said elongated external conductive elements are substantially comprised of a heavy metal of the group consisting of gold, silver, platinum, iron, aluminum, zinc and copper.

4. The catheter assembly of claim 3, wherein said elongated external conductive elements are substantially comprised of copper.

5. The catheter assembly of claim 1 wherein said power is provided by a battery source.

6. The catheter assembly of claim 1, wherein said hub further comprises:

(a) A cap adapted to removably seal said hub;

(b) at least two internal conductive elements disposed in a parallel spaced relation from each other along portions of the internal length of said hub, said internal conductive elements to be energized by an operably connected power source to create a second open circuit means, said second open circuit means inducing antimicrobial effect in the area proximate said hub through oligodynamic activity.

7. The catheter assembly of claim 6, wherein said cap contains a power source which becomes operably connected to said internal conductive elements to create said second open circuit means upon closure of said hub with said cap.

8. The catheter assembly of claim 7 wherein said power source comprises a battery source.

9. The catheter assembly of claim 6 wherein said internal conductive elements are substantially comprised of a material in the group consisting of gold, silver, platinum, iron, aluminum, zinc and copper.

10. The catheter assembly of claim 6, wherein said internal conductive elements are substantially comprised of copper.

11. A catheter assembly comprising:

(a) a catheter tube having a proximal end and a distal end to transmit fluid therethrough.

(b) a hub at the proximal end of said catheter tube to permit fluid flow through said catheter tube;

(c) at least two elongated external conductive elements fixedly disposed to be substantially parallel to each other along their entire length and helically surrounding the exterior circumference of a portion of said catheter tube, said elements forming portions of a first open circuit means upon application of power to said elements to induce an antimicrobial effect along portions of the exterior surface of said catheter tube through oligodynamic activity;

(d) a cap adapted to removably seal said hub;

(e) at least two internal conductive elements disposed in a parallel spaced relation from each other along portions of the internal length of said hub, said elements being energizable by power to create a second open circuit means, said second open circuit means inducing antimicrobial effect in the area proximate said hub through oligodynamic activity;

(f) a first power source which may be operably connected to apply power to said elongated external conductive elements to create said first open circuit means;

(g) a second power source contained within said cap, said second power source being operably connected to apply power to said internal conductive elements to create said second open circuit means upon closure of the hub with said cap.

12. The catheter assembly of claim 11 wherein said antimicrobial effect is induced within sequential fields of oligodynamic activity along any longitudinal radial segment of said catheter tube.