Device and method for inhibiting intravascular device associated infection

• US 5,324,276 A
• Filed: 01/11/1993
• Issued: 06/28/1994
• Est. Priority Date: 05/01/1991
• Status: Expired due to Fees

• Current Assignee: Paul H. Rosenberg
• Original Assignee: Paul H. Rosenberg
• Inventors: Rosenberg, Paul H.
• Primary Examiner(s): WEISS, JOHN
• Application Number:
  US08/002,585
• Time in Patent Office: 533 Days
• Field of Search: 604/264, 604/265, 604/266, 604/267, 604/268, 604/269, 604/280, 604/284, 604/164, 604/167, 604/172, 604/49, 604/51, 604/53
• US Class Current: 604/269
• CPC Class Codes: A61M 2025/0056 provided with an antibacterial agent, e.g. by coating, residing in the polymer matrix or releasing an agent out of a reservoir
• CPC Class Codes: A61M 25/0017 specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
• CPC Class Codes: A61M 25/007 Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked

Abstract

The present invention is directed to a device for reducing the risk of infection and/or clotting associated with the establishment and/or maintenance of fluid communication between apparatus external to the body and the interior of the body. The device includes a first tube insertable into the body. A second tube is disposed within the first tube, the second tube having a distal end portion insertable into the body and extending through an opening defined at the distal end of the first tube. The first and second tubes define therebetween a longitudinally coaxially disposed channel which establishes a fluid communication path for a first fluid. The first tube has one or more predeterminately-sized capillary apertures defined therein and predeterminately sized so as to predeterminately control the flow of a first fluid through the aperture, so that the first fluid remains substantially on and along the outer surface of the first tube so as to coat the outer surface of the first tube with the first fluid, thereby creating an anti-infective barrier which surrounds the intravascular device as it lies within the body. The second tube may also or alternatively include apertures for the selective coating and/or irrigation of the interior of the second tube to prevent infection or clotting therein.

Claims

1. A catheter insertable into a body for establishing a fluid communication path between a location external to the body and a site within the body, said catheter comprising:

a first elongated tube;

a second elongated tube disposed longitudinally within said first tube, said first tube having a portion sized so as to fluid-tightly sealingly engage said second tube, said first and second tubes defining therebetween a coaxial channel extending longitudinally along and within said first tube to define a first fluid communication path through which a first fluid is deliverable;

said second tube defining therewithin a second fluid communication path through and along which a second fluid is flowable between a location external to the body and a site within the body; and

said second tube having defined therethrough a plurality of predeterminately-sized apertures for delivering said first fluid from said channel to an interior portion of said second tube for allowing selective irrigation of said interior portion with the first fluid so as to discourage accumulations of unwanted matter on an interior surface of the second tube.

2. The catheter according to claim 1, wherein said plural predeterminately-sized apertures are disposed circumferentially about and longitudinally along said second tube.

3. The catheter according to claim 1, wherein said plural predeterminately-sized apertures are sized and disposed for predeterminately controlling the flow of the first fluid through said apertures such that as the first fluid is delivered from said channel into the second tube through said apertures, the first fluid remains substantially on and along the interior surface of said second tube so as to substantially coat said interior surface of the second tube with the first fluid.

4. The catheter according to claim 1, wherein said plural predeterminately-sized apertures are sized and disposed for predeterminately controlling the flow of the first fluid through said apertures such that as the first fluid is delivered under pressure from said channel through said apertures, the first fluid substantially flushes the second fluid communication path of said second tube.

5. The catheter according to claim 1, wherein said first tube comprises a distal end portion operatively insertable into the body, an opening defined at said first tube distal end portion, said second tube having a distal end portion insertable into the body through said first tube distal end opening, said first tube distal end opening being sized so as to fluid-tightly sealingly engage said second tube, said distal end of said second tube being capable of extension beyond the distal end of said first tube, said first and second tubes being longitudinally movable relative to each other for selective adjustment of the extension of said second tube outwardly beyond said first tube distal end through said first tube distal end opening.

6. The catheter according to claim 5, wherein said plural predeterminately-sized apertures are disposed circumferentially around and longitudinally along said second tube.

7. The catheter according to claim 5, wherein said plural predeterminately-sized apertures are sized and disposed for predeterminately controlling the flow of the first fluid through said apertures such that as the first fluid is delivered from said channel through said aperture, the first fluid remains substantially on and along the interior surface of said second tube so as to substantially coat said interior surface of the second tube with the first fluid.

8. The catheter according to claim 5, wherein said plural predeterminately-sized apertures are sized and disposed for predeterminately controlling the flow of the first fluid through said apertures such that as the first fluid is delivered under pressure from said channel through said apertures, the first fluid substantially flushes the second tube so as to prevent the accumulation of unwanted matter on and along the interior surface of said second tube.

9. The catheter according to claim 1, wherein said first fluid is selected from a group consisting of a non-specific anti-microbial short chain fatty acid, saline, free water, a liquid lubricant, an anti-coagulant liquid and heparin.

10. The catheter according to claim 1, wherein said apertures are substantially circular in cross-section.

11. The catheter according to claim 1, wherein said apertures are shaped as elongated slits oriented substantially along the longitudinal axis of said second tube.

12. The catheter according to claim 1, wherein said apertures are shaped as elongated slits oriented at an angle substantially transverse to the longitudinal axis of said second tube.

13. The catheter according to claim 1, wherein said first tube includes a plurality of predeterminately-sized secondary apertures defined therein for delivering the first fluid outwardly from said channel to an outer surface of said first tube.

14. The catheter of claim 13, wherein said predetermined size of said secondary apertures is selected for predeterminately controlling the flow of the first fluid through said secondary apertures so that as the first fluid is delivered outwardly from said channel through said secondary apertures, the first fluid remains substantially on and along the outer peripheral surface of said first tube so as to coat said first tube peripheral surface with the first fluid and thereby create a fluid barrier on and along the first tube peripheral surface disposed within the body.

15. The catheter according to claim 1, wherein each of said tubes is flexible.

16. In combination:

a device insertable into a body for establishing a fluid communication path between a location external to the body and a site within the body, said device comprising;

a catheter comprising a first elongated tube capable of insertion into the body, said first tube having an outer peripheral surface;

a second elongated tube disposed longitudinally within said first tube, said first tube having an opening sized so as to fluid-tightly sealingly engage said second tube, said first and second tubes defining therebetween a channel extending longitudinally along and within said first tube to define a fluid communication path; and

a fluid deliverable through said fluid communication path and deliverable from said fluid communication path through a plurality of predeterminately-sized apertures defined in and through said first tube and said second tube for delivering said first fluid from said channel to an outer surface of said first tube and to an interior portion of said second tube.

17. A method for introducing fluid to exterior and interior surfaces of a catheter to reduce medical risks normally associated with catheter placement in the body, comprising the steps of:

inserting, into the body, a first tube and a second tube disposed within the first tube to create a longitudinal channel defined coaxially between the first and second tubes;

delivering a fluid through said channel and outwardly from said channel through a plurality of apertures defined in said first tube and through a plurality of apertures in said second tube so that said fluid is simultaneously delivered to the exterior surface of said first tube and to the interior of said second tube.

18. The method according to claim 17, wherein said step of delivering fluid comprises delivering a fluid selected from a group consisting of a non-specific anti-microbial short chain fatty acid, saline, free water, a liquid lubricant, an anti-coagulant solution and heparin.

19. A method for introducing fluid to exterior and interior surfaces of a catheter to reduce medical risks normally associated with catheter placement in the body, comprising the steps of:

inserting, into the body, a first tube and a second tube disposed within the first tube to create a longitudinal channel defined coaxially between the first and second tubes;

delivering a fluid through said channel and outwardly from said channel through a plurality of capillary apertures defined in said first tube and predeterminately sized so that as the fluid is delivered outwardly through said capillary apertures from said channel the fluid remains substantially on and along the outer peripheral surface of the first tube so as to coat the first tube outer peripheral surface with the fluid and thereby create an anti-infective barrier along the outer peripheral surface of the first tube within the body; and

simultaneously delivering the fluid through a plurality of predeterminately-sized openings defined in and through said second tube for delivering the fluid from said channel to an interior portion of said second tube so as to provide selective irrigation of said second tube interior portion with the fluid so as to prevent the accumulation of unwanted matter on and along the interior surface of said second tube.

20. The method according to claim 19, wherein said steps of delivering fluid comprises delivering a fluid selected from a group consisting of a non-specific anti-microbial short chain fatty acid, saline, free water, a liquid lubricant, an anti-coagulant solution and heparin.