Multiwell test apparatus

• US 5,326,533 A
• Filed: 11/04/1992
• Issued: 07/05/1994
• Est. Priority Date: 11/04/1992
• Status: Expired due to Term

• Current Assignee: Millipore Corporation
• Original Assignee: Millipore Corporation
• Inventors: Zermani, Thomas, Lee, Carolyn, Rising, Donald
• Primary Examiner(s): WARDEN, JILL ALICE
• Application Number:
  US07/971,498
• Time in Patent Office: 608 Days
• Field of Search: 422/101, 435/301, 435/311, 210/455, 210/473
• US Class Current: 422/534
• CPC Class Codes: B01D 61/18 Apparatus therefor
• CPC Class Codes: B01D 61/28 Apparatus therefor
• CPC Class Codes: B01D 61/30 Accessories; Auxiliary operation
• CPC Class Codes: B01L 3/50255 Multi-well filtration

Abstract

A dialysis apparatus is provided including a multiwell plate, a separations membrane and a template having holes which mate with the wells. The membrane is sealed to one end of the wells by positioning the template about the outer peripheral surfaces of the wells with the membrane being frictionally held therebetween.

Claims

1. An apparatus suitable for separating liquid samples comprising:

a plate having a plurality of wells, each of said wells having a first open end, a second end and an outside peripheral surface,

a single separation membrane in sealing relationship with each of said second ends,

and a template having a plurality of holes of a size and arrangement corresponding to said wells,

said template being positioned so as to retain said membrane in sealing relationship with the second end and outside peripheral surface of each of said wells, and each second end extending through said template.

2. The apparatus of claim 1 including a container for a liquid composition in direct contact with said membrane sealed to the second end of said at least one well.

3. The apparatus of claim 1 including a shelf extending from an inner peripheral surface at said second end.

4. The apparatus of claim 1 wherein said membrane is a cellulosic.

5. The apparatus of claim 2 wherein said membrane is a cellulosic.

6. The apparatus of claim 3 wherein said membrane is a cellulosic.

7. The apparatus of claim 1 wherein said membrane is a dialysis membrane.

8. The apparatus of claim 1 wherein said membrane is a reverse osmosis membrane.

9. The apparatus of claim 1 wherein said membrane is an ultrafiltration membrane.