Method and apparatus for treatment of angina same
First Claim
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1. A method of electrical stimulation, comprising:
- placing an electrode in an appropriate location surrounding for stimulating the SA nodal fat pad of a human heart;
defining a first heart rate;
sensing the rate at which said human heart is beating;
providing said stimulus pulses to said electrode, synchronized to depolarizations of a chamber of said human heart, during refractory periods following said depolarizations, in response to the rate at which said heart is beating exceeding said first heart rate;
determining the effect of said stimulus pulses on the rate at which said human heart is beating; and
adjusting the amplitude of said stimulus pulses as a function of the determined effect of said stimulus pulses.
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Abstract
A stimulator for providing stimulus pulses to the SA nodal fat pad, in response to heart rate exceeding a predetermined level, in order to reduce the ventricular rate. The device is also provided with a cardiac pacemaker to pace the ventricle in the event that the stimulus pulses reduce the heart rate below a predetermined value. The device is also provided with a feedback regulation mechanism for controlling the parameters of the stimulation pulses applied to the AV nodal fat pad, as a result of their determined effect on heart rate.
373 Citations
20 Claims
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1. A method of electrical stimulation, comprising:
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placing an electrode in an appropriate location surrounding for stimulating the SA nodal fat pad of a human heart; defining a first heart rate; sensing the rate at which said human heart is beating; providing said stimulus pulses to said electrode, synchronized to depolarizations of a chamber of said human heart, during refractory periods following said depolarizations, in response to the rate at which said heart is beating exceeding said first heart rate; determining the effect of said stimulus pulses on the rate at which said human heart is beating; and adjusting the amplitude of said stimulus pulses as a function of the determined effect of said stimulus pulses. - View Dependent Claims (5, 6)
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2. A method of electrical stimulation, comprising the steps of:
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placing an electrode in an appropriate location for stimulating the SA nodal fat pad of a human heart; defining a first heart rate; sensing the rate at which said human heart is beating; providing said stimulus pulses to said electrode, synchronized to depolarizations of a chamber of said human heart, during refractory periods following said depolarizations, in response to the rate at which said heart is beating exceeding said first heart rate; defining a second heart rate below said first heart rate; and pacing said human heart when the rate at which said human heart is beating falls below said second heart rate. - View Dependent Claims (3, 4)
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7. An electrical medical stimulator, comprising:
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electrode means for delivery of electrical stimulation to the fat pad associated with the SA node of a human heart; means for sensing depolarizations of a chamber of said human heart to determine the rate at which said human heart is beating; pulse generator means responsive to said sensing means for generating stimulus pulses and for providing said stimulus pulses to said electrode means during the refractory period of said chamber of said heart; means for defining a first heart rate; initiating means responsive to said sensing means for initiating the operation of said pulse generator means in response to the rate of said human heart exceeding said first heart rate; means responsive to said sensing means and to said pulse generator means for determining the effect of said stimulus pulses on the rate of said human heart; and means for adjusting the energy of said stimulus pulses as a function of the detected effected of said stimulus pulses. - View Dependent Claims (8, 9, 10)
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11. An electrical medial stimulator, comprising:
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electrode means for delivery of electrical stimulation to the fat pad associated with the SA node of a human heart; means for sensing depolarizations of a chamber of said human heart to determine the rate at which said human heart is beating; pulse generator means for generating stimulus pulses and for providing said stimulus pulses to said electrode means; means for defining a first heart rate; initiating means responsive to said sensing means for initiating the operation of said pulse generator means in response to the rate of said human heart exceeding said first heart rate; means for sensing a physiologic parameter other than heart rate and for providing an output signal indicative thereof; and means for defining a first sensor threshold; and wherein said initiating means further comprises means responsive to said output signal meeting said sensor threshold for initiating the operation of said pulse generator means. - View Dependent Claims (12, 13, 15, 16, 17, 18, 19)
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14. An electrical medical stimulator, comprising:
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electrode means for delivery of electrical stimulation to the fat pad associated with the SA node of a human heart; means for sensing depolarizations of a chamber of said human heart to determine the rate at which said human heart is beating; pulse generator means responsive to said sensing means for generating stimulus pulses and for providing said stimulus pulses to said electrode means; means for defining a first heart rate; means for defining an acceptable range of heart rates; initiating means responsive to said sensing means for enabling the operation of said pulse generator means in response to the rate of said human heart exceeding said first heart rate; and means responsive to said sensing means and to said pulse generator means for determining the effect of said stimulus pulses on the rate of said human heart and means for adjusting the energy of said stimulus pulses, while said pulse generator is enabled, as a function of the determined effect of said stimulus pulses, to maintain said heart rate within said acceptable range of heart rates. - View Dependent Claims (20)
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Specification