Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same
First Claim
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1. A method for synthesizing a liposome having encapsulated therein a gas comprising contacting liposomes in an aqueous medium with gas under elevated pressures.
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Abstract
Liposomes suitable as ultrasound contrast agents which contain media of various types including gases, gaseous precursors activated by pH, temperature or pressure, as well as other solid or liquid contrast enhancing agents, are described. Methods of using the same as ultrasound contrast agents are also disclosed. The present invention also comprises novel methods for synthesizing liposomes having encapsulated therein gases.
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30 Claims
- 1. A method for synthesizing a liposome having encapsulated therein a gas comprising contacting liposomes in an aqueous medium with gas under elevated pressures.
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