Method and apparatus for determining body composition using bioelectrical impedance

• US 5,335,667 A
• Filed: 11/20/1992
• Issued: 08/09/1994
• Est. Priority Date: 11/20/1992
• Status: Expired due to Term

• Current Assignee: University of Utah Research Foundation (State of Utah)
• Original Assignee: University of Utah Research Foundation (State of Utah)
• Inventors: Cha, Kichul, Horch, Kenneth W.
• Primary Examiner(s): Sykes, Angela D.
• Application Number:
  US07/979,791
• Time in Patent Office: 627 Days
• Field of Search: 128/734, 128/741, 128/630, 128/632, 128/693, 128/774
• US Class Current: 600/547
• CPC Class Codes: A61B 5/0537 Measuring body composition by impedance, e.g. tissue hydration or fat content
• CPC Class Codes: A61B 5/4869 Determining body composition
• CPC Class Codes: A61B 5/4872 Body fat

Abstract

A method and apparatus for determining body composition of a subject is provided. The composition determinations can include total body fat, lean body mass, total body water, inter-cellular fluid and/or extra-cellular fluid. The subject'"'"'s body is treated as a plurality of segmented conductors, each of the body segments having a relatively uniform cross-sectional area. By determining the composition of one or more exemplary body segments, the total body composition can be determined. The method in accordance with the present invention selects one or more body segments and introduces a uniform current flow through the body segments. The impedance which each of the body segments presents to the current flow is measured by a pair of voltage sensing electrodes positioned at each end of the body segments. Preferred body segments include the subject'"'"'s thigh, trunk, and upper arm. The length of the body segment and its cross sectional area are used, as well as the gender of the subject, in combination with the bioelectrical impedance of the body segment to determine the body composition.

Claims

1. A method of determining the body composition of a subject comprising the steps of:

selecting a first body segment, the first body segment comprising substantially less than the whole body of the subject, and determining the characteristics of the first body segment utilizing a method comprising the steps of;

causing a current flow through the first body segment;

measuring the impedance to the current flow of the first body segment;

selecting a second body segment, the second body segment comprising substantially less than the whole body of the subject, and determining the characteristics of the second body segment utilizing a method comprising the steps of;

causing a current flow through the second body segment;

measuring the impedance to the current flow of the second body segment; and

determining the total body composition in accordance with measured impedance of the first body segment and the measured impedance of the second body segment.

2. A method of determining body composition as defined in claim 1 wherein the first body segment is chosen from a group consisting of the thigh, truck, and upper arm of the subject.

3. A method of determining body composition as defined in claim 1 further comprising measuring the length of the first body segment and the circumference of the first body segment and calculating a first body segment cross sectional area and wherein the step of determining the characteristics of the first body segment further comprises the step of determining the composition of the first body segment from the impedance derived from a voltage sensed at a first location and a second location on the subject'"'"'s body in combination with the measured length of the first body segment and the cross sectional area of the first body segment.

4. A method of determining body composition as defined in claim 3 wherein the step of measuring the circumference of the first body segment comprises the step of obtaining a plurality of circumference measurements each at a different location along the length of the first body segment.

5. A method of determining body composition as defined in claim 1 further comprising the step of determining the gender of the subject and wherein the step of determining the characteristics of the first body segment further comprises the step of considering the subject'"'"'s gender to determine the composition of at least the first body segment.

6. A method of determining body composition as defined in claim 1 wherein the step of determining the characteristics of the first body segment comprises the step of applying an equation of the form:

space="preserve" listing-type="equation">SBF.sub.v =C.sub.1 *F(ζ

.sub.a)+C.sub.2 (sex)/A.sub.T +C.sub.3 (sex)

wherein;

SBF_v is segmental body fat on a volume fraction basis,

F(ζ

_a) is the segmental specific impedance or its inverse,

A_T is segmental average cross-sectional area,

(sex) indicates a gender dependent constant, and the coefficients of the variables are determined from empirical data collection.

7. A method of determining body composition as defined in claim 1 wherein the subject comprises four extremities and wherein the step of causing a current flow through the first body segment and wherein the step of causing a current flow through the second body segment together comprise the step of attaching an electrode to the distal portion of each of the subject'"'"'s extremities.

8. A method of determining body composition as defined in claim 1 wherein the step of measuring the impedance to the current flow of the first body segment comprises the step of attaching a first electrode at a first end of the first body segment and measuring the voltage thereat and the step of attaching a second at a second end of the first body segment and measuring the voltage thereat.

9. A method of determining body composition as defined in claim 1 further comprising the step of determining the gender of the subject and wherein the step of determining the characteristics of the first body segment further comprises the step of considering the subject'"'"'s gender to determine the first body segment'"'"'s composition.

10. A method of determining body composition as defined in claim 1 further comprising the step of estimating the composition of the entire subject'"'"'s body.

11. A method of determining body composition as defined in claim 1 wherein the body composition material is one selected from a group consisting of fat, lean body mass, total body water, inter-cellular fluid, and extra-cellular fluid.

12. A method of determining body composition as defined in claim 1 further comprising the steps of:

selecting a third body segment, the third body segment comprising substantially less than the whole body of the subject and determining the characteristics of the third body segment utilizing a method comprising the steps of;

causing a current flow through the third body segment; and

measuring the impedance to the current flow of the third body segment.

13. A method of determining the body composition of a subject, the subject having four extremities, the method comprising the steps of:

injecting a current into a distal portion of a first extremity of the subject'"'"'s body;

injecting a current into a distal portion of a second extremity of the subject'"'"'s body simultaneously with that injected into the first extremity;

injecting a current into a distal portion of a third extremity of the subject'"'"'s body simultaneously with that injected into the first and second extremities;

injecting a current into a distal portion of a fourth extremity of the subject'"'"'s body simultaneously with that injected into the first, second, and third extremities;

selecting a first body segment, the first body segment comprising substantially less than the whole body of the subject;

sensing the voltage at a first location on the first body segment;

sensing the voltage at a second location on the first body segment to arrive at the bioelectrical impedance of the first body segment, the second location on the first body segment being spaced apart from the first location on the first body segment;

selecting a second body segment, the second body segment comprising substantially less than the whole body of the subject;

sensing the voltage at a first location on the second body segment;

sensing the voltage at a second location on the second body segment to arrive at the bioelectrical impedance of the second body segment, the second location on the second body segment being spaced apart from the first location on the second body segment; and

determining the composition of the subject'"'"'s body using the voltages sensed at the first body segment and the second body segment of the subject'"'"'s body.

14. A method of determining the body composition of a subject as defined in claim 13 wherein the first body segment is one chosen from a group consisting of the thigh, truck, and upper arm segments of the subject.

15. A method of determining the body composition of a subject as defined in claim 13 further comprising the steps of measuring the length of the first body segment and measuring the circumference of the first body segment and calculating a first body segment cross sectional area and wherein the step of determining the composition of the subject'"'"'s body further comprises the step of determining the composition of the first body segment from the bioelectrical impedance derived from the voltage sensed at the first location and at the second location on the first body segment of the subject'"'"'s body in combination with the measured length of the first body segment and the cross sectional area of the first body segment.

16. A method of determining the body composition of a subject as defined in claim 15 further comprising the steps of determining the gender of the subject and the step of determining the composition of the subject'"'"'s body further comprises the step of considering the subject'"'"'s gender to determine the composition of subject'"'"'s body.

17. A method of determining the body composition of a subject as defined in claim 13 wherein the step of determining the composition of the subject'"'"'s body comprises the step of determining the composition of the first body segment by applying an equation of the form:

space="preserve" listing-type="equation">SBF.sub.v =C.sub.i *F(ζ

.sub.a)+C.sub.2 (sex)/A.sub.T +C.sub.3 (sex)

where

SBF_v is segmental body fat on a volume fraction basis,

F(ζ

_a) is the segmental specific impedance or its inverse,

A_T is segmental average cross-sectional area,

(sex) indicates a gender dependent constant, and the coefficients of the variables are determined from empirical data collection.

18. A method of determining the body composition of a subject as defined in claim 13 wherein the body composition material is one selected from a group consisting of fat, lean body mass, total body water, inter-cellular fluid, and extra-cellular fluid.

19. A method of determining the amount of fat contained in at least a portion of the body of a subject, the subject having two arms and two legs, the method comprising the steps of:

attaching a first electrode to a distal portion of the subject'"'"'s first arm;

providing a current to the first electrode;

attaching a second electrode to a distal portion of the subject'"'"'s second arm;

providing a current to the second electrode;

attaching a third electrode to a distal portion of the subject'"'"'s first leg;

providing a current to the third electrode;

attaching a fourth electrode to a distal portion of the subject'"'"'s second leg;

providing a current to the fourth electrode;

selecting a first body segment, the first body segment comprising substantially less than the whole body of the subject;

attaching a fifth electrode to a first end of the first body segment;

attaching a sixth electrode to a second end of the first body segment;

measuring the voltage difference between the fifth electrode and the sixth electrode to determine the bioelectrical impedance of the first body segment;

measuring the distance between the fifth electrode and the sixth electrode;

measuring the circumference of the first body segment; and

calculating the amount of fat in the first body segment based upon the voltage difference and the distance between the fifth and sixth electrodes and the diameter of the first body segment.

20. A method of determining the amount of fat contained in at least a portion of the body of a subject as defined in claim 19 wherein the first body segment is one chosen from a group consisting of the thigh, truck, and upper arm segments of the subject.

21. A method of determining the amount of fat contained in at least a portion of the body of a subject as defined in claim 19 further comprising the steps of

moving the fifth electrode to a first end of a second body segment;

moving the sixth electrode to a second end of a second body segment;

measuring the voltage difference between the fifth electrode and the sixth electrode to determine the bioelectrical impedance of the second body segment;

measuring the distance between the fifth electrode and the sixth electrode on the second body segment;

measuring the circumference of the second body segment; and

calculating the amount of fat in the second body segment based upon the voltage difference and the distance between the fifth and sixth electrodes and the diameter of the second body segment.

22. A method of determining the amount of fat contained in at least a portion of the body of a subject as defined in claim 19 further comprising the step of determining the gender of the subject and wherein the step of calculating the amount of fat in the first body segment further comprises the step of considering the subject'"'"'s gender to determine the composition of the first body segment.

23. A method of determining the amount of fat contained in at least a portion of the body of a subject as defined in claim 19 wherein the step of calculating the amount of fat in the first body segment comprises the step of calculating the amount of fat in the first body segment by applying an equation of the form:

space="preserve" listing-type="equation">SBF.sub.v =C.sub.l *F(ζ

.sub.a)+C.sub.2 (sex)/A.sub.T +C.sub.3 (sex)

where

SBF_v is segmental body fat on a volume fraction basis,

F(ζ

_a) is the segmental specific impedance or its inverse,

A_T is segmental average cross-sectional area,

(sex) indicates a gender dependent constant, and the coefficients of the variables are determined from empirical data collection.

24. A method of determining the amount of fat contained in at least a portion of the body of a subject as defined in claim 19 further comprising the step of calculating the amount of material in the first body segment wherein the material is one selected from a group consisting of lean body mass, total body water, intra-cellular fluid, and extra-cellular fluid.

25. A method of determining the body composition of at least a portion of a subject, the subject having four extremities, the method comprising the steps of:

injecting a current into a distal portion of a first extremity of the subject'"'"'s body;

injecting a current into a distal portion of a second extremity of the subject'"'"'s body simultaneously with that injected into the first extremity;

injecting a current into a distal portion of a third extremity of the subject'"'"'s body simultaneously with that injected into the first and second extremities;

injecting a current into a distal portion of a fourth extremity of the subject'"'"'s body simultaneously with that injected into the first, second, and third extremities;

selecting a first body segment, the first body segment comprising substantially less than the whole body of the subject.

sensing the voltage at a first location on the first body segment;

sensing the voltage at a second location on the first body segment, the second location being spaced apart from the first location; and

determining the composition of at least the first body segment from an impedance derived from the voltage sensed at the first location and the second location of the subject'"'"'s body.

26. An apparatus for determining the bioelectrical impedance of at least a portion of a subject having four extremities, the apparatus comprising:

current means for generating a current;

means for injecting the current into a distal portion of a first extremity of the subject'"'"'s body;

means for injecting the current into a distal portion of a second extremity of the subject'"'"'s body;

means for injecting the current into a distal portion of a third extremity of the subject'"'"'s body;

means for injecting the current into a distal portion of a fourth extremity of the subject'"'"'s body;

voltage means for measuring voltage found on the subject'"'"'s body;

means for sensing a first voltage present at a first location on the subject'"'"'s body and conveying the first voltage to the voltage means;

means for sensing second voltage present at a second location on the subject'"'"'s body, the second location being spaced apart from the first location, and conveying the second voltage to the voltage means; and

means for outputting an impedance of the subject'"'"'s body between the means for sensing a first voltage and the means for sensing a second voltage.

27. An apparatus for determining the bioelectrical impedance of at least a portion of a subject as defined in claim 26 wherein the first location is one end of a body segment and the second location is the opposite end of the body segment wherein the body segment is one selected from a group consisting of a thigh segment, a truck segment, and an upper arm segment of the subject.

28. An apparatus for determining the bioelectrical impedance of at least a portion of a subject as defined in claim 26 wherein the means for injecting the current into a distal portion of a first extremity and the means for injecting the current into a distal portion of a second extremity comprises a pair of electrodes each connected in parallel and connected to a constant current source.