Method of testing for leakage in a solution pumping system

• US 5,336,053 A
• Filed: 01/29/1993
• Issued: 08/09/1994
• Est. Priority Date: 01/29/1993
• Status: Expired due to Term

• Current Assignee: Hospira Incorporated (Pfizer Inc.)
• Original Assignee: Abbott Laboratories
• Inventors: Wynkoop, Richard D.
• Primary Examiner(s): Bertsch, Richard A.
• Assistant Examiner(s): Thorpe, Timothy S.
• Application Number:
  US08/010,728
• Time in Patent Office: 557 Days
• Field of Search: 417/9, 417/53, 417/413 R, 73/40, 73/168
• US Class Current: 417/53
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 2205/70 with testing or calibration facilities
• CPC Class Codes: A61M 5/16854 by monitoring line pressure
• CPC Class Codes: F04B 43/04 Pumps having electric drive
• CPC Class Codes: F04B 51/00 Testing machines, pumps, or pumping installations

Abstract

A method of testing a pumping system including a pump cassette effects pressurization of the system, with subsequent monitoring of any pressure loss in the system. This is achieved by closing any inlets and outlets of the cassette, and thereafter over-pressurizing the cassette beyond its normal operating range. Pressure measurements are taken before and after a specified time interval, with any significant pressure loss indicating system leakage. In the preferred practice, the diaphragm of the pump cassette is first subjected to cold flow, or "creep", thereby minimizing the influence of cold flow of the diaphragm on subsequent pressure measurement.

Claims

1. A method of testing a pumping system including pump means which creates a positive liquid pressure in the system during a pumping stroke, said method comprising the steps of:

operating said pump means to create a positive liquid pressure within the pumping system;

measuring the pressure of liquid in the system to obtain a first liquid pressure P₁ ;

waiting a predetermined time interval after measurement of pressure P₁ ;

measuring the pressure of liquid in the system to obtain a second liquid pressure P₂ ;

comparing the pressure P₁ to the pressure P₂ to ascertain any drop in pressure in the system; and

providing a signal indicating leakage in the system when the difference between P₁ and P₂ exceeds a predetermined value.

2. The method of testing a pumping system in accordance with claim 1, wherein

each of said steps of measuring the pressure of liquid in the system includes obtaining an average pressure of said system over a predetermined time interval.

3. The method of testing a pumping system in accordance with claim 1, wherein

said step of operating said pump means includes first operating said pump means to create a relatively high liquid pressure in the system, and thereafter operating said pump means to reduce the pressure in the system prior to measuring the pressure to obtain pressure P₁.

4. A method of operating a pumping system, including positive displacement pump means having a deformable pump diaphragm which is displaced for creating positive liquid pressure in the system, the method comprising the steps of:

displacing said pump diaphragm to a first position to create a relatively high pressure in the system to stretch the pump diaphragm;

maintaining said pump diaphragm in said first position for a predetermined time interval; and

thereafter operating said pump means at a system pressure less than said relatively high pressure, with said displacing and maintaining steps acting to reduce the influence of any of cold flow of said diaphragm.

5. A method of operating a pumping system in accordance with claim 4, including

moving said diaphragm to a second position, monitoring the liquid pressure in said system to detect any leakage in the system.

6. A method of operating a pumping system in accordance with claim 5, wherein

said monitoring step includes:

measuring the pressure of liquid in the system to obtain a first liquid pressure P₁,

waiting a predetermined time interval,

measuring the pressure of liquid in the system to obtain a second liquid pressure P₂,

comparing the pressure P₁ to the pressure P₂, and providing a signal indicating leakage in the system when the difference between P₁ and P₂ exceeds a predetermined value.

7. The method of operating a pumping system in accordance with claim 6, wherein

each of said steps of measuring the pressure of liquid in the system includes obtaining an average pressure of said system over a predetermined time interval.

8. A method of testing a pump cassette of a pumping system including a pump driver having a reciprocable pump piston, said pump cassette having pump means including a diaphragm positionable in operative association with the pump piston, the method comprising the steps of:

operating said pump driver to close liquid inlets and outlets of said pump cassette;

advancing said pump piston to displace said diaphragm to a first position to pressurize liquid in the cassette;

maintaining said pump diaphragm in said first position for a predetermined time interval;

retracting said pump piston so that said diaphragm moves to a second piston where said diaphragm is displaced less than in said first position;

measuring the pressure of liquid in the cassette of the system to obtain a first liquid pressure P₁ ;

waiting a predetermined time interval after measurement of P₁ ;

measuring the pressure of liquid in the cassette of the system to obtain a second liquid pressure P₂ ;

comparing the pressure P₁ to the pressure P₂ to ascertain any drop in pressure in the cassette of the system; and

providing a signal indicating leakage in the cassette of the system when the difference between P₁ and P₂ exceeds a predetermined value.

9. The method of testing of claim 8, when

each of said steps of measuring the pressure of liquid in the system includes obtaining an average pressure of said system over a predetermined time interval.

10. A method of operating a pump system, including positive displacement pump means having a deformable pump diaphragm which is displaced for creating positive liquid pressure in the system, the method comprising the steps of:

displacing said pump diaphragm to create a relatively high pressure in the system to stretch the pump diaphragm;

maintaining sufficiently high pressure in said system for a sufficient time interval to subject said stretched diaphragm to cold flow; and

thereafter operating said pump means at a system pressure less than said relatively high pressure, with said displacing and maintaining steps acting to reduce the influence of cold flow of said diaphragm on subsequent operation of said pump means.