Method of forming a membrane, especially a latex membrane, having a biocide barrier

• US 5,338,565 A
• Filed: 11/16/1992
• Issued: 08/16/1994
• Est. Priority Date: 07/17/1987
• Status: Expired due to Term

• Current Assignee: Alec Beck
• Original Assignee: Robin R.T. Shlenker
• Inventors: Smith, Clayton S., Plunkett, Jerry D., Shlenker, Robin R. T., Solomons, Clive C.
• Primary Examiner(s): LUSIGNAN, MICHAEL R
• Application Number:
  US07/976,881
• Time in Patent Office: 638 Days
• Field of Search: 2/167, 2/168, 128/844, 427/2, 427/407.1, 523/122, 604/96, 604/332, 606/236, 424/404
• US Class Current: 427/2.25
• CPC Class Codes: A01N 25/10 Macromolecular compounds
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A41D 19/0058 Three-dimensional gloves
• CPC Class Codes: A41D 19/0096 Means for resisting mechanical agressions, e.g. cutting or piercing
• CPC Class Codes: A41D 31/245 using layered materials
• CPC Class Codes: A61B 42/00 Surgical gloves; Finger-stalls specially adapted for surgery; Devices for handling or treatment thereof
• CPC Class Codes: A61F 6/04 Condoms, sheaths or the like , e.g. combined with devices protecting against contagion
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 2300/442 Colorants, dyes
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: A62D 5/00 Composition of materials for coverings or clothing affording protection against harmful chemical agents
• CPC Class Codes: B32B 27/18 characterised by the use of special additives

Abstract

Methods of forming a chemical barrier against the transmission of disease-causing microbes and other harmful agents through a membrane such as latex. In the principal method, a mold or former is coded with a coagulant, which is dried, and then the former is dipped into liquid latex, which is allowed to gel, and then the former is dipped into a solution containing the biocide, and then the former is dipped again into the liquid latex, after which the entire coating on the former is cured. Alternatively, the biocide may be sprayed or otherwise applied onto the gelled latex.

Claims

1. A method of making a material having a biocide barrier comprising the steps of:

applying a first coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers onto a former;

applying a coating of biocide over the first coating already on the former; and

applying a second coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers over the biocide and the first coating.

2. The method of claim 1, wherein said biocide is selected from the group consisting of gentian violet, dextran sulphate, benzalkonium, betadyne, gentian violet, acriflavine and acridine dyes, mercurochrome, silver salts, and an extract of blue green algae.

3. The method of claim 1, wherein said biocide is in a solution that coats over the first coating and said biocide is in a concentration substantially in the range of 0.10 percent to five percent by weight.

4. The method of claim 1, wherein said biocide is in a solution that coats over the first coating and wherein the ratio of the mass of the biocide solution coating to the mass of the first coating is substantially in the range of 0.05 to 0.3.

5. The method of claim 1, wherein said biocide coating is applied by dipping the first coating into a vat of biocide solution.

6. The method of claim 1, wherein said biocide coating is applied by spraying the biocide over the first coating.

7. The method of claim 1, wherein said biocide coating is applied over the first coating when the first coating is in a vat gel state.

8. The method of claim 1, comprising the further step of at least partial leaching of the first coating prior to applying the biocide coating.

9. The method of claim 1, wherein said biocide is in a solution that coats over the first coating and wherein said solution is substantially completely dried prior to applying the second coating.

10. A method of making a material having a biocide barrier comprising the steps of:

applying a first coating of biocide onto a former; and

applying a coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers over the biocide coating already on the former.

11. The method of claim 10, wherein said biocide is selected from the group consisting of dextran sulphate, benzalkonium, betadyne, gentian violet, acriflavine and acridine dyes, mercurochrome, silver salts, and an extract of blue green algae.

12. The method of claim 10, wherein said biocide is in a solution that coats over the first coating and said biocide is in a concentration substantially in the range of 0.10 percent to five percent by weight.

13. The method of claim 10, wherein said biocide is in a solution that coats over the first coating and wherein the ratio of the mass of the biocide solution coating to the mass of the first coating is substantially in the range of 0.05 to 0.2.

14. A method of making an article selected from the group consisting of gloves, condoms, diaphragms, slippers, overshoes, sterile bands, catheters, tubing, drapes, gut openings, mouthpieces, nipples, intra gastric nasal tubes, kidney shunts, dams for teeth, braces for teeth, sub-clavian vein and artery shunts, and colostomy bags having a biocide barrier comprising the steps of:

applying a first coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers onto a former;

applying a coating of biocide over the first coating already on the former; and

applying a second coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers over the biocide and the first coating.

15. A method of making an article selected from the group consisting of gloves, condoms, diaphragms, slippers, overshoes, sterile bands, catheters, tubing, drapes, gut openings, mouthpieces, nipples, intra gastric nasal tubes, kidney shunts, dams for teeth, braces for teeth, sub-clavian vein and artery shunts, and colostomy bags having a biocide barrier comprising the steps of:

applying a first coating of biocide onto a former; and

applying a coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers over the biocide coating already on the former.

16. A method of making an article selected from the group consisting of gloves, condoms, diaphragms, slippers, overshoes, sterile bands, catheters, tubing, drapes, gut openings, mouthpieces, nipples, intra gastric nasal tubes, kidney shunts, dams for teeth, braces for teeth, sub-clavian vein and artery shunts, and colostomy bags having a biocide barrier comprising the steps of:

applying a first coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers onto a former;

applying a coating of biocide comprising gentian violet over the first coating already on the former; and

applying a second coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers over the biocide and the first coating.

17. The method of claim 16, wherein said biocide is in a solution that coats over the first coating and said biocide is in a concentration substantially in the range of 0.10 percent to five percent by weight.

18. The method of claim 16, wherein said biocide is in a solution that coats over the first coating and wherein the ration of the mass of the biocide solution coating to the mass of the first coating is substantially in the range of 0.05 to 0.3.

19. The method of claim 16, wherein said biocide coating is applied by dipping the first coating into a vat of biocide solution.

20. The method of claim 16, wherein said biocide coating is applied by spraying the biocide over the first coating.

21. The method of claim 16, wherein said biocide coating is applied over the first coating when the first coating is in a wet gel state.

22. The method of claim 16, comprising the further step of at least partial leaching of the first coating prior to applying the biocide coating.

23. The method of claim 16 wherein said biocide is in a solution that coats over the first coating and wherein said solution is substantially completely dried prior to applying the second coating.

24. A method of making an article selected from the group consisting of gloves, condoms, diaphragms, slippers, overshoes, sterile bands, catheters, tubing, drapes, gut openings, mouthpieces, nipples, intra gastric nasal tubes, kidney shunts, dams for teeth, braces for teeth, sub-clavian vein and artery shunts, and colostomy bags having a biocide barrier comprising the steps of:

applying a first coating of a biocide comprising gentian violet onto a former; and

applying a coating of a liquid material selected from the group consisting of polymeric latex, a polymer dissolved in a solvent, and liquid polymers over the biocide coating already on the former.