Apparatus and method for increasing the amplitude of P300 waves in the human brain
First Claim
1. A system for providing electrical stimulation to a human being and thereby increasing amplitude of P300 wave activity in a brain of said human being, said human being having a forehead and a wrist, said system comprising:
- a source for generating a substantially periodic electrical waveform;
a first electrode means for connecting said source to the forehead of said human being; and
a second electrode means for connecting said source to the wrist of said human being wherein said source produces said substantially periodic waveform having an amplitude in a range of approximately 0.1 to 400 mA, a frequency in a range of 50 to 300 Hz and a pulse width of greater than 0.2 milliseconds and less than 2.0 milliseconds.
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Abstract
A cranial electrotherapy stimulation ("CES") device which generates periodic electrical signals is connected between the forehead and wrist area of a human being in order to affect electrical activity in the brain and thereby decrease the individual'"'"'s craving for controlled substances such as alcohol and drugs and reduce anxiety, insomnia and depression. A portable, cranial electrical stimulator is preferably mounted adjacent the arm area or worn about the waist of a patient. A first electrode is attached to the forehead of the patient, preferably above the bridge of the nose between the eyes, and a second electrode is attached to the wrist area of one am, preferably at the radial artery. Periodic electrical pulses having a waveform with a current amplitude in the range of 0.1 to 60 mA, a voltage of approximately 40-60 volts, a frequency of approximately 0.1 to 400 Hz, and a pulse width approximately 0.2 to 2 milliseconds at a 20% duty cycle are applied for at least 20 minutes between the forehead and wrist electrode. As a result, electrical activity in the brain is affected, in particular, the amplitude of P300 electrical brain activity is increased. Since decreased P300 activity is associated with increased patient interest in drugs and alcohol, the use of the CES in the is way makes it less likely that the patient will desire such controlled substances.
116 Citations
16 Claims
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1. A system for providing electrical stimulation to a human being and thereby increasing amplitude of P300 wave activity in a brain of said human being, said human being having a forehead and a wrist, said system comprising:
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a source for generating a substantially periodic electrical waveform; a first electrode means for connecting said source to the forehead of said human being; and a second electrode means for connecting said source to the wrist of said human being wherein said source produces said substantially periodic waveform having an amplitude in a range of approximately 0.1 to 400 mA, a frequency in a range of 50 to 300 Hz and a pulse width of greater than 0.2 milliseconds and less than 2.0 milliseconds. - View Dependent Claims (2)
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3. A method of increasing amplitude of P300 waves in a skull of a human being, said human being having a forehead and a wrist, comprising the steps of:
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attaching a first electrode to the forehead of said human being; attaching a second electrode to the wrist of said human being; and applying a substantially periodic electrical signal between said first electrode and said second electrode wherein said electrical signal has a frequency in a range of 50 to 300 Hz, an amplitude in a range of 0.1 to 60 mA, and a pulse width greater than 0.2 milliseconds and less than 2.0 milliseconds. - View Dependent Claims (4)
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5. A method of increasing the amplitude of P300 waves in a brain of a human being, said human being having a head and wrist, comprising the steps of:
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attaching a first electrode means to the head of said human being; attaching a second electrode means to said wrist of said human being; and
,applying between said first and second electrode means a substantially periodic waveform having a frequency in a range of 50 to 300 Hz, a current amplitude of approximately 0.1 to 400 mA, a voltage in a range of 40 to 60 volts, and a pulse width greater than 0.2 milliseconds and less than 20 milliseconds at a duty cycle of about 20% for at least 20 minutes. - View Dependent Claims (6, 7, 8, 9, 10, 11)
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12. An apparatus for providing electrical stimulation to a human being and thereby increasing amplitude of P300 wave activity in a brain of said human being, said human being having a forehead and a wrist, said apparatus comprising:
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a source for generating a substantially periodic electrical waveform, said source including a cranial electrotherapy stimulation device which produces said substantially periodic waveform having an amplitude in a range of approximately 0.1 to 400 mA, a frequency in a range of approximately 50 to 300 Hz and a pulse width of greater than 0.20 milliseconds and less than 2.0 milliseconds; a first electrode means for connecting said source to the forehead of said human being; and a second electrode means for connecting said source to the wrist of said human being. - View Dependent Claims (13, 14, 15, 16)
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Specification