Photoplethysmographics using energy-reducing waveform shaping

• US 5,343,818 A
• Filed: 03/05/1991
• Issued: 09/06/1994
• Est. Priority Date: 03/05/1991
• Status: Expired due to Term

• Current Assignee: Sensormedics Corporation (Becton, Dickinson & Co)
• Original Assignee: Sensormedics Corporation (Becton, Dickinson & Co)
• Inventors: Smith, Robert, McCarthy, Rex
• Primary Examiner(s): Cohen, Lee S.
• Assistant Examiner(s): NASSER, ROBERT L
• Application Number:
  US07/664,782
• Time in Patent Office: 1,281 Days
• Field of Search: 128/633, 128/664-666, 356/41, 250/343, 364/413.03
• US Class Current: 600/310
• CPC Class Codes: A61B 5/1455 using optical sensors, e.g. spectral photometrical oximeters
• CPC Class Codes: A61B 5/417 the bone marrow

Abstract

A method of energy-reducing waveform shaping of carrier signals in a photoplethysmographic system, in which a carrier signal may comprise a time-varying periodic waveform comprising a sum of carrier components. The carrier signal has its energy reduced by adding additional carrier components, which reduce the energy envelope for a period of the carrier signal, while preserving the signal information. The method of energy-reducing waveform shaping may be coupled with frequency-division, phase-division and component-amplitude-division multiplexing, and more generally with any method of multiplexing which employs a time-varying periodic carrier signal. Redundant information may be used for error detection and correction. A plurality of carrier components may be chosen which reduces the energy envelope for a period of the carrier signal, and which employs more carrier components than needed to perform the preferred form of multiplexing and demultiplexing of the modulation effects introduced by a tissue section of the patient. Majority voting of carrier components may then provide for error detection and correction.

Claims

1. A device for collecting photoplethysmographic data, comprising

means for generating a first and a second signal, said first and second signals each comprising at least one carrier component, each said carrier component having a component energy, wherein at least one of said first and second signals has a plurality of said carrier components and has an energy less than the sum of its respective component energies;

means for applying said first and second signal to a modulating medium;

means for detecting a composite signal at an output of said modulating medium, said modulating medium having a first and a second modulating effect; and

means for generating a first and a second output signal responsive to said composite signal, said first output signal corresponding to said first modulating effect applied to said first signal and said second output signal corresponding to said second modulating effect applied to said second signal.

2. A device as in claim 1, comprising means for determining, in response to a set of photoplethysmographic data, blood gas data.

3. A device as in claim 1, comprising means for determining, in response to a set of photoplethysmo-graphic data, at least one of blood oxygen, blood carbon dioxide, or blood carbon monoxide.

4. A device as in claim 1, wherein said means for generating a first and a second signal comprises means for generating first and second signals which comprise differing frequency spectra.

5. A device as in claim 1, wherein said means for generating a first and a second signal comprises means for generating first and second signals which comprise disjoint sets of carrier components.

6. A device as in claim 1, wherein said means for generating a first and a second signal comprises means for generating first and second signals which are periodic time-varying signals with differing periods.

7. A device as in claim 1, wherein said means for generating comprises means for generating first and second signals which comprise identical frequency spectra.

8. A device as in claim 1, wherein said means for generating comprises means for generating first and second signals which comprise identical sets of carrier components.

9. A device as in claim 1, wherein said means for generating comprises means for generating first and second signals which are periodic time-varying signals with identical periods.

10. A device as in claim 1, wherein said means for generating comprises means for generating first and second signals which differ in phase with respect to at least one said carrier component.

11. A device as in claim 1, wherein said means for generating comprises means for generating first and second signals which are periodic time-varying signals which are identical except for phase.

12. A device as in claim 1, wherein said means for generating comprises means for generating first and second signals which differ in amplitude for at least one carrier component.

13. A device as in claim 1, wherein said means for generating comprises means for generating first and second signals which are periodic time-varying signals which are identical except for amplitude of carrier components.

14. A device as in claim 1, wherein said means for generating a first and a second signal comprises means for generating at least one signal comprising a plurality of component signals, at least one of said carrier components comprising a sum of at least one of a sine wave or, a square wave.

15. A device as in claim 1, wherein said means for applying comprises a plurality of light-emitters.

16. A device as in claim 1, wherein said means for applying comprises a plurality of light-emitters tuned to at least two differing wavelengths.

17. A device as in claim 1, wherein said means for applying comprises means for directing at least one of said first and second signals at animal tissue.

18. A device as in claim 1, wherein said means for applying comprises means for directing at least one of said first and second signals toward at least one of blood, blood vessels, bone marrow, ligament, muscle, or skin.

19. A device as in claim 1, wherein said means for detecting comprises a photodiode.

20. A device as in claim 1, wherein said means for detecting a composite signal comprises means for detecting a sum of said first modulating effect applied to said first signal and said second modulating effect applied to said second signal.

21. A device as in claim 1, wherein said means for detecting a composite signal comprises means for detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said modulating effects comprises amplitude modulation.

22. A device as in claim 1, wherein said means for detecting a composite signal comprises means for detecting a composite signal comprising a result of a plurality of modulating effects, wherein said first and second modulating effects comprise an amplitude modulation effect which varies with energy wavelength.

23. A device as in claim 1, wherein said means for detecting a composite signal comprises means for detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprises a time-varying component.

24. A device as in claim 1, wherein said means for detecting a composite signal comprises means for detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprises a time-varying component which is correlated with a biological process.

25. A device as in claim 1, wherein said means for detecting a composite signal comprises means for detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprises at least one transmission response of said modulating medium at a predetermined frequency.

26. A device for collecting photoplethysmographic data, comprising

means for generating a first and a second signal, said first and second signals each comprising at least one carrier component, each said carrier component having a component energy, wherein said first signal has a plurality of said carrier components and has an energy less than the sum of its component energies;

means for applying said first and second signal to a modulating medium;

means for detecting a composite signal at an output of said modulating medium, said modulating medium having a first and a second modulating effect; and

means for generating a first and a second output signal responsive to said composite signal, said first output signal corresponding to said first modulating effect applied to said first signal and said second output signal corresponding to said second modulating effect applied to said second signal.

27. A device for collecting photoplethysmographic data, comprising

means for generating a plurality of signals, said plurality of signals each comprising at least one component signal, each said component signal having a component energy, wherein at least one of said plurality of signals has a plurality of said carrier components and has an energy less than the sum of its respective component energies;

means for applying said plurality of signals to a modulating medium;

means for detecting a composite signal at an output of said modulating medium, said modulating medium having a first and a second modulating effect; and

means for generating a first and a second output signal responsive to said composite signal, said first output signal corresponding to said first modulating effect applied to said first signal and said second output signal corresponding to said second modulating effect applied to said second signal.

28. A method for collecting photoplethysmographic data, comprising the steps of

generating a first and a second signal, said first and second signals each comprising at least one carrier component, each said carrier component having a component energy, wherein at least one of said first and second signals has a plurality of said carrier components and has an energy less than the sum of its respective component energies;

applying said first and second signal to a modulating medium;

detecting a composite signal at an output of said modulating medium, said modulating medium having a first and a second modulating effect; and

generating a first and a second output signal responsive to said composite signal, said first output signal corresponding to said first modulating effect applied to said first signal and said second output signal corresponding to said second modulating effect applied to said second signal.

29. A method as in claim 28, comprising the step of determining, in response to a set of photoplethysmographic data, blood gas data.

30. A method as in claim 28, comprising the step of determining, in response to a set of photoplethysmographic data, at least one of blood oxygen, blood carbon dioxide, or blood carbon monoxide.

31. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals having differing frequency spectra.

32. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals having disjoint sets of carrier components.

33. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which are periodic time-varying signals with differing periods.

34. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which comprise identical frequency spectra.

35. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which comprise identical sets of carrier components.

36. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which are periodic time-varying signals with identical periods.

37. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which differ in phase with respect to at least one said carrier component.

38. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which are periodic time-varying signals which are identical except for phase.

39. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which differ in amplitude for at least one carrier component.

40. A method as in claim 28, wherein said step of generating said first and second signals comprises generating said first and second signals which are periodic time-varying signals which are identical except for amplitude of carrier components.

41. A method as in claim 28, wherein said step of generating a first and a second signal comprises the step of generating at least one signal comprising a plurality of carrier components, at least one of said carrier components comprising a sum of at least one of the group:

a sine wave, a square wave.

42. A method as in claim 28, wherein said step of applying comprises the step of directing at least one of said first and second signals at animal tissue.

43. A method as in claim 28, wherein said step of applying comprises the step of directing at least one of said first and second signals toward at least one of blood, blood vessels, bone marrow, ligament, muscle, or skin.

44. A method as in claim 28, wherein said step of detecting a composite signal comprises the step of detecting a composite signal which comprises a sum of said first modulating effect applied to said first signal and said second modulating effect applied to said second signal.

45. A device as in claim 28, wherein said step of detecting a composite signal comprises the step of detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprises amplitude modulation.

46. A method as in claim 28, wherein said step of detecting a composite signal comprises the step of detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprise an amplitude modulation effect which varies with energy wavelength.

47. A method as in claim 28, wherein said step of detecting a composite signal comprises the step of detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprises a time-varying component.

48. A method as in claim 28, wherein said step of detecting a composite signal comprises the step of detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprises a time-varying component which is correlated with a biological process.

49. A method as in claim 28, wherein said step of detecting a composite signal comprises the step of detecting a composite signal comprising a result of a plurality of modulating effects, wherein at least one of said first and second modulating effects comprises at least one transmission response of said modulating medium at a predetermined frequency.

50. A method for collecting photoplethysmographic data, comprising the steps of

generating a first and a second signal, said first and second signals each comprising at least one carrier component, each said carrier component having a component energy, wherein said first signal has a plurality of said carrier components and has an energy less than the sum of its component energies;

applying said first and second signal to a modulating medium;

detecting a composite signal at an output of said modulating medium, said modulating medium having a first and a second modulating effect; and

generating a first and a second output signal responsive to said composite signal, said first output signal corresponding to said first modulating effect applied to said first signal and said second output signal corresponding to said second modulating effect applied to said second signal.

51. A method for collecting photoplethysmographic data, comprising the steps of

generating a plurality of signals, said plurality of signals each comprising at least one component signal, each said component signal having a component energy, wherein at least one of said plurality of signals has a plurality of said carrier components and has an energy less than the stun of its respective component energies;

applying said plurality of signals to a modulating medium;

detecting a composite signal at an output of said modulating medium, said modulating medium having a first and a second modulating effect; and

generating a first and a second output signal responsive to said composite signal, said first output signal corresponding to said first modulating effect applied to said first signal and said second output signal corresponding to said second modulating effect applied to said second signal.