Intracavity probe and interface device for MRI imaging and spectroscopy

• US 5,348,010 A
• Filed: 09/24/1992
• Issued: 09/20/1994
• Est. Priority Date: 02/24/1989
• Status: Expired due to Term

• Current Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Original Assignee: Medrea Incorporated Pennsylvania Corporation PA, Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Inventors: Claiborne, Theodore C., Rhinehart, Edward J., Misic, George J., Lenkinski, Robert E., Schnall, Mitchell D., Welch, Thomas R., Kressel, Herbert Y., Pollack, Howard M.
• Primary Examiner(s): Smith, Ruth S.
• Application Number:
  US07/949,918
• Time in Patent Office: 726 Days
• Field of Search: 128/653.2, 128/653.5, 324/318, 324/322
• US Class Current: 600/422
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/4381 Prostate evaluation or disorder diagnosis
• CPC Class Codes: A61M 2025/1013 with concentrically mounted balloons, e.g. being independently inflatable
• CPC Class Codes: A61M 25/1002 characterised by balloon shape A61M25/1006, A61M25/1009 take precedence
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: G01R 33/34007 Manufacture of RF coils, e.g. using printed circuit board technology; additional hardware for providing mechanical support to the RF coil assembly or to part thereof, e.g. a support for moving the coil assembly relative to the remainder of the MR system
• CPC Class Codes: G01R 33/34084 implantable coils or coils being geometrically adaptable to the sample, e.g. flexible coils or coils comprising mutually movable parts
• CPC Class Codes: G01R 33/341 comprising surface coils
• CPC Class Codes: G01R 33/3657 Decoupling of multiple RF coils wherein the multiple RF coils do not have the same function in MR, e.g. decoupling of a transmission coil from a receive coil

Abstract

An insertable pickup probe and interface network for magnetic resonance imaging and spectroscopy. The pickup probe in the preferred embodiment is for use in imaging the male prostate and comprises an elongated shaft supporting a patient interface balloon at its distal end which contains a RF receiving coil. The interface balloon comprises an inflatabe inner balloon enclosed by a flexible outer balloon. The receiving coil is positioned between the inner and outer balloons and placed intimately adjacent the region of interest by inflating the inner balloon to expand outwardly against the outer balloon. In addition, a non-stretchable planar material is provided on the surface on the inner balloon adjacent the receiving coil for ensuring that the receiving coil is placed adjacent the region of interest. The inner balloon is inflated by an inflator cuff connected to the shaft and communicated to the inner balloon by a first lumen in the shaft. The receiving coil is electrically connected to an interconnecting cable which is connected to the proximal end of the shaft and communicated to the receiving coil by a second lumen in the shaft. An interface network is also provided which receives the interconnecting cable of the pickup probe and includes impedance matching means, tuning means, and decoupling means for interfacing the probe with a magnetic resonance imaging scanner. In addition, the interface includes an electronic circuit for automatically adjusting the control voltage of a varactor diode in a Pi network which comprises the tuning means.

Claims

1. A method for obtaining magnetic resonance information from a region of interest within a cavity of a patient using an insertable probe having a RF receiving coil between an inner and outer balloon, the method comprising the steps of:

inserting the probe into a predetermined position in the cavity of the patient;

inflating the inner balloon and controlling the inflation of the inner balloon with a non-stretchable substantially planar member covering a surface on the inner balloon, thereby inflating the outer balloon against the cavity and positioning the coil proximate the region of interest;

inducing magnetic resonance RF signals in the region of interest; and

receiving the RF signals with the coil.

2. A method of magnetic resonance imaging of a region of interest within a cavity of a patient with an insertable probe having a RF receiving device movable with an inflatable interface device, the method comprising the steps of:

inserting the probe into a predetermined position in the cavity of the patient;

inflating the interface device into contact with the cavity, thereby causing an anterior saddle shaped surface of the interface device to conformally fit against a shaped portion of the cavity proximate the region of interest, and securely positioning the RF receiving device proximate the region of interest;

inducing RF signals in the region of interest;

receiving the RF signals with the RF receiving device; and

producing a magnetic resonance image derived from the received RF signals.

3. The method of claim 2 further comprising the steps of:

impedance matching the output impedance of the received RF signals with an input impedance of a scanner;

tuning the resonant frequency of the RF receiving device to the Larmour frequency of the scanner;

decoupling the RF receiving device from the scanner when inducing RF signals in the region of interest to prevent distortion of the received RF signals.

4. A method of magnetic resonance imaging of a region of interest within a cavity of a patient with an insertable probe having a RF receiving device movable with an inflatable interface device, the method comprising the steps of:

inserting the probe into a predetermined position in the cavity of the patient;

inflating the interface device into contact with the cavity, thereby causing an anterior saddle shaped surface of the interface device to conformally fit against a shaped portion of the cavity proximate the region of interest, and securely positioning the RF receiving device proximate the region of interest;

inducing RF signals in the region of interest;

receiving the RF signals with the RF receiving device;

producing a magnetic resonance image derived from the received RF signals; and

wherein the inflatable interface device comprises an inner and outer balloon, the RF receiving device being expandable with the inflating of the inner balloon, the method further comprising the step of controlling the inflation of the inner balloon with a non-stretchable substantially planar member covering a surface on the inner balloon.

5. A method for obtaining magnetic resonance information from a region of interest within a cavity of a patient using an insertable probe, the method comprising the steps of:

(a) providing a probe having an inflatable inner balloon and outer positioning means surrounding the inner balloon, the outer positioning means having undulating folds extending away from the region of interest;

(b) providing an RF receiving coil between the inner balloon and the outer positioning means;

(c) inserting the probe into a predetermined position in the cavity of a patient;

(d) inflating the inner balloon to first unfold the undulating folds of the outer positioning means against a wall of the cavity generally opposite the region of interest;

(e) continuing to inflate the inner balloon and securely position the RF receiving coil between the inner balloon and the outer positioning means and proximate the region of interest;

(f) inducing RF signals in the region of interest;

(g) receiving the RF signals with the RF receiving device; and

(h) producing a magnetic resonance image derived from the received RF signals.