Peritoneal dialysis systems employing a liquid distribution and pumping cassette that emulates gravity flow

• US 5,350,357 A
• Filed: 03/03/1993
• Issued: 09/27/1994
• Est. Priority Date: 03/03/1993
• Status: Expired due to Term

• Current Assignee: Deka Products Limited Partnership
• Original Assignee: Deka Products Limited Partnership
• Inventors: Kamen, Dean, Vincent, Douglas E., Spencer, Geoffrey P.
• Primary Examiner(s): KRUTER, JEROME
• Application Number:
  US08/027,328
• Time in Patent Office: 573 Days
• Field of Search: 604/29-31
• US Class Current: 604/29
• CPC Class Codes: A61M 1/1524 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1561 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/288 Priming priming in extracorporeal blood circuits A61M1/3643
• CPC Class Codes: A61M 2205/12 with interchangeable cassettes forming partially or totally the fluid circuit
• CPC Class Codes: A61M 5/1486 the bags being substantially completely surrounded by fluid
• CPC Class Codes: Y10S 210/929 Hemoultrafiltrate volume measurement or control processes

Abstract

Peritoneal dialysis systems apply fluid pressure to move liquid. The systems can emulate either a fixed head height condition or different head height conditions, independent of the actual head height differential between the patient'"'"'s peritoneal cavity and the external liquid source or destination. The systems can also switch between low-relative pressure flow mode when considerations of patient comfort and safety predominate and a high-relative pressure flow mode when considerations of processing speed predominate.

Claims

1. A system for performing peritoneal dialysis comprising

a pumping mechanism comprising a diaphragm,

means for establishing flow communication with the patient'"'"'s peritoneal cavity through the pumping mechanism, and

actuating means for emulating a selected gravity flow condition by applying fluid pressure to the diaphragm to operate the pumping mechanism to either move dialysis solution from the peritoneal cavity or move dialysis solution into the peritoneal cavity, and

control means selectively operating the actuating means for applying fluid pressure to emulate either a fixed head height condition or different head height conditions.

2. A system according to claim 1

wherein the actuating means applies pneumatic fluid pressure.

3. A system according to claim 1

wherein the actuating means applies fluid pressure that is below atmospheric pressure.

4. A system according to claim 1

wherein the actuating means applies fluid pressure that is above atmospheric pressure.

5. A system according to claim 1

wherein, in a first mode of operation, the actuating means applies a first magnitude of fluid pressure and, in a second mode of operation, the actuating means applies a second magnitude of fluid pressure different than the first magnitude.

6. A system according to claim 1

and further including valve means for normally isolating the patient'"'"'s peritoneal cavity from the pumping mechanism including means for selectively opening the valve means to accommodate movement of the dialysis solution to and from the patient'"'"'s peritoneal cavity.

7. A system according to claim 6

wherein the valve means is operated in response to fluid pressure.

8. A system according to claim 6

wherein the valve means is operated in response to pneumatic pressure.

9. A peritoneal dialysis system comprising

a pumping mechanism comprising a pump chamber, at least one valve communicating with the pump chamber, and a diaphragm,

means for establishing flow communication between the pumping mechanism and the patient'"'"'s peritoneal cavity,

actuating means for emulating gravity flow conditions by applying fluid pressure to the diaphragm to operate the pump chamber and valve to:

(i) drain spent peritoneal dialysis solution from the patient'"'"'s peritoneal cavity, and

(ii) infuse fresh dialysis solution from a source into the patient'"'"'s peritoneal cavity, and

control means selectively operating the actuating means for applying fluid pressure to emulate either a fixed head height condition or different head height conditions.

10. A system according to claim 9

wherein the actuating means applies pneumatic fluid pressure.

11. A system according to claim 9

wherein the actuating means applies fluid pressure that is below atmospheric pressure.

12. A system according to claim 9

wherein the actuating means applies fluid pressure that is above atmospheric pressure.

13. A system according to claim 9

wherein, in a first mode of operation, the actuating means applies a first magnitude of fluid pressure and, in a second mode of operation, the actuating means applies a second magnitude of fluid pressure different than the first magnitude.

14. A peritoneal dialysis system comprising

means defining a pump chamber that has a diaphragm,

patient conduit means for establishing flow communication between the pump chamber and patient'"'"'s peritoneal cavity,

an other conduit means for establishing flow communication between the pump chamber and an external component outside the patient'"'"'s peritoneal cavity,

means for applying fluid pressure to the diaphragm to pump dialysis solution through patient conduit means and the other conduit means, and

pressure regulation means for applying fluid pressure variations to the diaphragm of a first magnitude when liquid is conveyed through the patient conduit means and for applying fluid pressure to the diaphragm of a second magnitude different than the first magnitude when liquid is conveyed through the other conduit means.

15. A system according to claim 14

wherein the first magnitude is less than the second magnitude.

16. A system according to claim 14

and further including means for varying the magnitudes of the pressure applied to the diaphragm to emulate different head height conditions.

17. A system according to claim 14

wherein the actuating means applies pneumatic pressure.

18. A system according to claim 14

wherein the actuating means applies fluid pressure that is below atmospheric pressure.

19. A system according to claim 14

wherein the actuating means applies fluid pressure that is above atmospheric pressure.

20. A peritoneal dialysis system comprising

means defining a pump chamber that has a diaphragm,

conduit means for establishing flow communication among the patient'"'"'s peritoneal cavity, a source of fresh dialysis solution, and a drain through the pump chamber,

actuating means for applying fluid pressure to the diaphragm to move spent peritoneal dialysis solution from the patient'"'"'s peritoneal cavity to the drain through the pump chamber and to pump fresh dialysis solution from the source to the patient'"'"'s peritoneal cavity through the pump chamber,

means for directing fluid flow through the pump chamber including

means for directing spent peritoneal dialysis solution from the patient'"'"'s peritoneal cavity into the pump chamber,

means for directing the spent dialysis solution from the pump chamber to the drain,

means for directing fresh dialysis solution from the source into the pump chamber, and

means for directing the fresh dialysis solution from the pump chamber to the patient'"'"'s peritoneal cavity, and

pressure regulation means for applying fluid pressure to the diaphragm of a first magnitude when liquid is conveyed through the pump chamber to and from the patient'"'"'s peritoneal cavity and for applying fluid pressure variations to the diaphragm of a second magnitude different than the first magnitude when liquid is conveyed through the pump chamber either to the drain or from the source container.

21. A system according to claim 20

and further including means for adjusting the magnitude of the fluid pressure variations applied to the diaphragm to emulate different head height conditions.

22. A system according to claim 20

wherein the actuating means applies pneumatic pressure.

23. A system according to claim 20

wherein the actuating means applies fluid pressure that is below atmospheric pressure.

24. A system according to claim 20

wherein the actuating means applies fluid pressure that is above atmospheric pressure.

25. A peritoneal dialysis system comprising

means defining a pump chamber that has a diaphragm,

conduit means for establishing flow communication among the patient'"'"'s peritoneal cavity, a source of fresh dialysis solution, a reservoir for heating the fresh dialysis solution, and a drain through the pump chamber,

actuating means for applying fluid pressure to the diaphragm to move liquid through the pump chamber,

means for directing liquid flow through the pump chamber including

means for directing spent peritoneal dialysis solution from the patient'"'"'s peritoneal cavity into the pump chamber,

means for directing the spent dialysis solution from the pump chamber to the drain,

means for directing fresh dialysis solution from the source into the pump chamber,

means for directing the fresh dialysis solution from the pump chamber to the reservoir for heating,

means for directing the heated fresh dialysis solution from the reservoir into the pump chamber, and

means for directing the heated fresh dialysis solution from the pump chamber to the patient'"'"'s peritoneal cavity, and

pressure regulation means for applying fluid pressure to the diaphragm of a first magnitude when liquid is conveyed through the pump chamber to and from the patient'"'"'s peritoneal cavity and for applying fluid pressure to the diaphragm of a second magnitude different than the first magnitude when liquid is conveyed through the pump chamber either to the drain;

or from the source container;

or to and from the reservoir.

26. A system according to claim 25

and further including means for adjusting the fluid pressure applied to the diaphragm to emulate different head height conditions.

27. A system according to claim 25

wherein the means for establishing flow communication includes

patient conduit means for establishing flow communication between the pump chamber and the patient'"'"'s peritoneal cavity, and

an other conduit means for establishing flow communication between the pump chamber and a component other than the patient'"'"'s peritoneal cavity, and

wherein the actuator includes pressure regulation means for the pressure conveying means to convey fluid pressure to the diaphragm of a first magnitude when liquid is moved through the patient conduit means and to convey fluid pressure to the diaphragm of a second magnitude different than the first magnitude when liquid is moved through the other conduit means.

28. A system according to claim 27

wherein the actuator includes control means for the pressure conveying means operable in a first mode for conveying fluid pressure to emulate a fixed head height condition.

29. A system according to claim 28

wherein the control means is operable in a second mode for varying the magnitude of the conveyed fluid pressure to emulate different head height conditions.

30. A system according to claim 27

wherein the pressure conveying means conveys pneumatic pressure.

31. A system according to claim 27

wherein the pressure conveying means conveys fluid pressure that is below atmospheric pressure.

32. A system according to claim 27

wherein the pressure conveying means applies fluid pressure that is above atmospheric pressure.

33. A system according to claim 25

wherein the first magnitude of fluid pressure is less than the second magnitude of fluid pressure.

34. A system for performing peritoneal dialysis comprising

a pumping mechanism comprising a diaphragm,

means for establishing flow communication with the patient'"'"'s peritoneal cavity through the pumping mechanism, and

actuating means for emulating a selected gravity flow condition by applying pneumatic fluid pressure to the diaphragm to operate the pumping mechanism to either move dialysis solution from the peritoneal cavity or move dialysis fluid into the peritoneal cavity, the actuating means including a chamber for receiving pneumatic pressure and insert means occupying the chamber for stabilizing the applied pneumatic pressure within the chamber.

35. A system according to claim 34

wherein the insert is made of an open cell porous material.