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Surface plasmon resonance measuring instruments

  • US 5,351,127 A
  • Filed: 06/17/1992
  • Issued: 09/27/1994
  • Est. Priority Date: 06/17/1992
  • Status: Expired due to Term
First Claim
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1. A surface plasmon resonance (SPR) instrument, comprising:

  • a block of material transparent to an electromagnetic beam, the block of material having a first surface;

    a crystalline material having an amplitude that is electrically modulated, the amplitude corresponding to an adjustable index of refraction, having a second surface for providing internal reflection of the electromagnetic beam;

    a source of electricity supplying electricity with adjustable amplitude to modulate the adjustable index of refraction of said crystalline material;

    a conductive layer adjacent to the second surface, the conductive layer adapted to contact a sample;

    an electromagnetic beam radiating to the second surface to produce internal reflection; and

    a detector of electromagnetic radiation coupled to the block for detecting reflection of the source beam from the second surface.

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