Human heart valve replacement with porcine pulmonary valve

• US 5,352,240 A
• Filed: 05/31/1989
• Issued: 10/04/1994
• Est. Priority Date: 05/31/1989
• Status: Expired due to Term

• Current Assignee: Cryolife Incorporated
• Original Assignee: Promedica International, Inc.
• Inventors: Ross, Donald N.
• Primary Examiner(s): Isabella, David
• Application Number:
  US07/359,478
• Time in Patent Office: 1,952 Days
• Field of Search: 623/1, 623/2, 623/3, 623/11, 623/66
• US Class Current: 600/36
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: Y10S 623/904 Heart

Abstract

A method of treating heart valve dysfunction in a human patient in which the dysfunctioning valve is replaced with a novel bioprosthesis. The novel bioprosthesis comprises a porcine pulmonary valve, which has preferably been treated to fix and also sterilize the valve tissue. The porcine pulmonary valve may either be stent mounted to facilitate its surgical implantation into the patient, or it may be unstented to reduce the possibility of embolism and thrombosis.

Claims

1. A method of treating aortic or pulmonary valve dysfunction in a human patient, comprising replacing the existing dysfunctioning valve with a fixed and sterilized whole excised unstented pulmonary porcine valve.

2. A method as in claim 1 wherein the porcine valve includes a section of porcine pulmonary artery associated with the porcine valve.

3. A method as in claim 1 wherein said porcine valve has attached thereto a flexible sewing skirt extending from the inlet side of the porcine valve to facilitate suturing of the valve in the patient.

4. A method of treating aortic or pulmonary valve dysfunction in a human patient comprising fixing and sterilizing an unstented pulmonary porcine valve, and replacing the existing dysfunctioning valve with the fixed and sterilized whole unstented pulmonary porcine valve.

5. A method of treating aortic or pulmonary valve dysfunction in a human patient comprising excising a whole porcine pulmonary valve and associated section of porcine pulmonary artery, fixing and sterilizing the pulmonary porcine valve and artery, and replacing the existing dysfunctioning valve with the fixed and sterilized whole pulmonary porcine valve which is unstented.

6. A method of treating aortic or pulmonary valve dysfunction in a human patient comprising excising a whole porcine pulmonary valve and associated section of porcine pulmonary artery, fixing and sterilizing the pulmonary porcine valve and artery, attacing a flexible sewing skirt to the porcine valve extending from the inlet side thereof to facilitate suturing of the valve in the patient, and replacing the existing dysfunctioning valve with the fixed and sterilized whole pulmonary porcine valve which is unstented.