Minimally invasive medical device for providing a radiation treatment

• US 5,354,257 A
• Filed: 01/29/1991
• Issued: 10/11/1994
• Est. Priority Date: 01/29/1991
• Status: Expired due to Term

• Current Assignee: Cook Medical Technologies, LLC (Cook Group Incorporated)
• Original Assignee: MED Institute, Inc. (Cook Group Incorporated)
• Inventors: Roubin, Gareth S. S., Fearnot, Neal E.
• Primary Examiner(s): Green, Randall L.
• Assistant Examiner(s): ZUTTARELLI, ANTHONY
• Application Number:
  US07/647,280
• Time in Patent Office: 1,351 Days
• Field of Search: 600/3, 600/7, 128/653.1, 128/654, 128/657, 128/659, 128/772, 604/164, 604/282, 250/496.1, 250/497.1
• US Class Current: 600/7
• CPC Class Codes: A61B 2017/22068 Centering
• CPC Class Codes: A61M 2025/1047 having centering means, e.g. balloons having an appropriate shape
• CPC Class Codes: A61N 2005/1003 having means for centering a radioactive source within the lumen, e.g. balloons
• CPC Class Codes: A61N 2005/1004 having expandable radiation sources
• CPC Class Codes: A61N 2005/1021 Radioactive fluid
• CPC Class Codes: A61N 2005/1025 Wires
• CPC Class Codes: A61N 5/1002 Intraluminal radiation therapy

Abstract

A minimally invasive intravascular medical device for providing a radiation treatment in a body passageway such as a coronary vessel of the vascular system. The device includes a flexible elongated member having distal and proximal portions. The distal portion is percutaneously insertable into a vessel and includes a distal end that is directable through the vessel to the treatment site. A radiation source is attached about the distal portion for delivering a radiation treatment to the walls a vessel having a stent positioned thereagainst. The distal portion of the elongated member includes a wire coil positioned about the tapered distal end of a mandril wire. The combination of the wire coil and the tapered distal end of the mandril wire provides variable flexibility to the distal portion of the device. The distal portion also has a predetermined curvature for directing the distal end of the device through the vessel. A safety wire is also extendable through the passageway of the wire coil to provide further flexibility to the distal portion. The radiation source is fixedly positioned about either the tapered distal end of the mandril wire or the safety wire in the passageway of the wire coil. An annular recess is included about the tapered distal end of the mandril wire to fixedly position a source of radioactive material therein.

Claims

1. A minimally invasive intravascular medical device for providing a radiation treatment, comprising:

a cylindrical first wire having a first uniform outer diameter and a longitudinally tapered distal end;

a wire coil including a distal end, a proximal end, and a passageway extending longitudinally therebetween, said tapered distal end of said first wire extending longitudinally in said passageway of said wire coil, said proximal end of said wire coil being attached to said first wire, said coil having a second outer diameter within a predetermined tolerance of said first uniform outer diameter, said wire coil having a predetermined longitudinal curvature;

a second wire having a distal end attached to said wire coil and a proximal end and extending longitudinally in said passageway to said tapered distal end of said first wire, said proximal end of said second wire being attached to said wire coil and said first wire in said longitudinal passageway; and

a sleeve of radioactive material fixedly positioned at least partially around said second wire in said passageway a predetermined distance from said distal end of said wire coil.

2. A minimally invasive medical device for providing a radiation treatment in a body passageway, comprising:

a flexible elongated member tube having a proximal portion, a distal portion, and a hollow passageway extending longitudinally therethrough, said distal portion being insertable in said body passageway over a guide positioned therein and having a distal end directable through said body passageway over the guide; and

a radiation source fixedly positioned and embedded in said tube around said hollow passageway of said tube.

3. The device of claim 2 further comprising a wire guide slidable through said hollow passageway of said tube.

4. A minimally invasive medical device for providing a radiation treatment in a body passageway, comprising:

a flexible elongated member having a proximal portion, a distal portion, and a first wire having a tapered distal end extending longitudinally in said distal portion, said distal portion being insertable in said body passageway and having a predetermined longitudinal curvature and a distal end directable through said body passageway, said distal portion also including a wire coil having a distal end, a proximal end, and a passageway extending longitudinally therebetween, said tapered distal end of said first wire extending longitudinally in said passageway of said wire coil and being attached to said wire coil; and

a radiation source attached at least partially around said tapered distal end of said first wire.

5. The device of claim 4 wherein said tapered distal end of said first wire includes an annular recess and said radiation source is fixedly positioned in said annular recess.

6. The device of claim 4 wherein said distal portion includes a second wire having a proximal end attached to said wire coil and to said first wire and a distal end attached to said wire coil and extending longitudinally in said passageway of said wire coil.

7. The device of claim 6 wherein said proximal end of said second wire extends and is attached to said proximal end of said wire coil.

8. The device of claim 7 wherein said wire coil has a first predetermined outer diameter and wherein a proximal portion of said first wire has a second predetermined outer diameter within a predetermined tolerance of said first outer diameter.

9. A minimally invasive intravascular medical device for providing a radiation treatment, comprising:

a first wire having a longitudinally tapered distal end;

a wire coil positioned around said tapered distal end of and attached to said first wire and having a distal end, a proximal end, and a passageway extending longitudinally therebetween; and

a radiation source attached at least partially around said first wire in said passageway of said wire coil.

10. The device of claim 9 wherein said wire coil has a predetermined longitudinal curvature.

11. The device of claim 10 wherein said radiation source includes radioactive material fixedly positioned at least partially around said tapered distal end of said first wire in said passageway.

12. The device of claim 10 wherein said tapered distal end of said first wire includes an annular recess and wherein said radiation source includes radioactive material fixedly positioned in said annular recess.

13. The device of claim 10 further comprising a second wire attached to said wire coil and extending longitudinally in said passageway to said first wire.

14. The device of claim 13 wherein said radiation source includes radioactive material fixedly positioned at least partially around said second wire in said passageway a predetermined distance from said distal end of said wire coil.