Delivery apparatus with pressure controlled delivery

• US 5,354,273 A
• Filed: 12/14/1992
• Issued: 10/11/1994
• Est. Priority Date: 12/14/1992
• Status: Expired due to Term

• Current Assignee: Mallinckrodt Medical Inc. (Mallinckrodt plc)
• Original Assignee: Mallinckrodt Medical Inc. (Mallinckrodt plc)
• Inventors: Hagen, Ronald W.
• Primary Examiner(s): KRUTER, JEROME
• Application Number:
  US07/988,266
• Time in Patent Office: 666 Days
• Field of Search: 604/65-67, 128/DIG. 1, 128/DIG. 12
• US Class Current: 604/66
• CPC Class Codes: A61M 2005/14513 with secondary fluid driving or regulating the infusion
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 2230/50 Temperature
• CPC Class Codes: A61M 5/14526 the piston being actuated by fluid pressure
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: A61M 5/16836 by sensing tissue properties at the infusion site, e.g. for detecting infiltration detecting tissue temperature for diagnostic purposes A61M39/0247
• CPC Class Codes: A61M 5/16854 by monitoring line pressure
• CPC Class Codes: A61M 5/48 having means for varying, regulating, indicating or limiting injection pressure A61M5/142 takes precedence ; monitoring pressure in infusion systems A61M5/16854
• CPC Class Codes: Y10S 128/12 Pressure infusion

Abstract

A delivery apparatus for delivering various media, such as medical and/or pharmaceutical media or the like, from a delivery device, such as a syringe, in which the delivery pressure of the medium as it is dispensed from the delivery device is automatically maintained and regulated at a preselected level throughout delivery of the medium from the delivery apparatus. In one embodiment, the skin temperature of the patient is also sensed and the pressure of the medium being administered to the patient is further adjusted in response to the sensed skin temperature.

Claims

1. A delivery apparatus for delivering a stored medium from a variable volume delivery device in which mechanical actuating means are provided for expelling the stored medium from the delivery device through a delivery tip at one end thereof, said delivery apparatus comprising:

fixture means for receiving and positioning said delivery device;

said fixture means including force generating and application means for applying an actuating force to said mechanical actuating means of said delivery device to subject the stored medium in said variable volume chamber to a pressure for the expulsion of said medium from said chamber through said delivery tip;

said fixture means further including an opening therein for receiving said delivery tip and positioning the same for connection to a use application;

pressure sensing means for sensing and generating a signal proportional to the magnitude of the pressure in said medium resulting from the force applied by said force generating and application means;

reference pressure generating means for generating a reference pressure signal representing a preselected desired reference pressure magnitude for the pressure in said medium resulting from the actuating force applied by said applicator means;

comparator means for comparing the signal generated by said pressure sensing means with said reference pressure signal and for generating a difference signal proportional to the difference between the signal generated by said pressure sensing means and said reference pressure signal;

control means for controlling the magnitude of the force applied by said applicator means; and

means connecting said difference signal to said control means for controlling the magnitude of the force applied by said applicator means in a direction to reduce the magnitude of said difference signal to zero, whereby said applied force is automatically regulated to maintain a pressure in said medium at the level represented by said reference pressure signal.

2. A delivery apparatus as set forth in claim 1 in which said pressure sensing means includes means for sensing the pressure in said medium at a point downstream of the delivery tip of said delivery device.

3. A delivery apparatus as set forth in claim 1 in which said pressure sensing means includes means for sensing the pressure in said medium at the point of delivery to a patient.

4. A delivery apparatus as set forth in claims 1, 2 or 3 in which said force generating and application means includes a compartment and a piston and means for applying an actuating pressure to said piston and said force sensing means includes means for sensing the pressure applied to said piston.

5. A delivery apparatus as set forth in claims 1, 2 or 3 in which said force generating and application means includes an electric motor and said force sensing means includes current sensing means for sensing the current flowing to said electric motor.

7. A delivery apparatus as set forth in claim 4 in which said delivery device comprises a prefilled container containing a pressure sensitive medium to be dispensed from the container.

10. A delivery apparatus as set forth in claim 1 further including temperature sensing means for sensing the skin temperature of a patient to whom the medium is being administered and for adjusting the delivery pressure of said medium in response to said temperature sensing means.

6. A delivery apparatus for delivering a stored medium from a variable volume delivery device in which mechanical actuating means are provided for expelling the stored medium from the delivery device through a delivery opening thereof, said delivery apparatus comprising:

a delivery device having a variable volume chamber for storing a medium to be delivered from said delivery device;

a delivery opening connected to said variable volume chamber through which said stored medium is expelled;

said delivery device including actuating means for varying the volume of said chamber to expel the stored medium from said variable volume chamber through said delivery opening;

fixture means for receiving said delivery device;

said fixture means including force generating and application means for applying an actuating force to said actuating means of said delivery device, whereby the stored medium in said variable volume chamber is subjected to a pressure for the expulsion of said medium from said chamber through said opening;

pressure sensing means for sensing and generating a signal proportional to the magnitude of the pressure in said medium resulting from the force applied by said force generating and application means;

reference pressure generating means for generating a reference pressure signal representing a preselected desired pressure magnitude in said medium resulting from the actuating force applied by said applicator means;

comparator means for comparing the signal generated by said pressure sensing means with said reference pressure signal and for generating a difference signal proportional to the difference between the signal generated by said pressure sensing means and said reference pressure signal;

control means for controlling the magnitude of the force applied by said applicator means; and

means connecting said difference signal to said control means for controlling the magnitude of the force applied by said applicator means in a direction to reduce the magnitude of said difference signal to zero, whereby said applied force is automatically regulated to maintain a pressure in said medium at the level represented by said reference pressure signal.

8. A delivery apparatus as set forth in claims 6 or 7 in which said pressure sensing means includes means for sensing the pressure in said medium at a point downstream of the delivery tip of said delivery device.

9. A delivery apparatus as set forth in claims 6 or 7 in which said pressure sensing means includes means for sensing the pressure in said medium at the point of delivery to a patient.