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Method for use in treating a patient with FK 506 to prevent an adverse immune response

  • US 5,365,948 A
  • Filed: 08/21/1992
  • Issued: 11/22/1994
  • Est. Priority Date: 08/21/1992
  • Status: Expired due to Fees
First Claim
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1. A method for treating a patient to prevent an adverse immune response by partially suppressing the patient'"'"'s immune system without unduly suppressing the ability of the immune system to combat infection, comprising the steps of:

  • (a) administering an initial dose of FK 506 to the patient;

    (b) examining the patient to determine information concerning patient examination criteria;

    (c) assigning a characterization to each of the patient examination criteria, each such characterization being selected from a predetermined standardized range of characterizations applicable to each patient examination criterion;

    (d) providing the assigned characterizations to a computing device comprising;

    a knowledge base comprising rules which include one of a plurality of treatment instructions in response to at least one of various combinations of the characterizations which can be assigned to the patient examination criteria, andan expert computer program including a first routine for prompting, through an output means, a user to enter, through an input means, the assigned characterizations;

    a second routine for selecting a treatment instruction by locating a rule which covers the assigned characterizations, and thereby determines the treatment instruction; and

    a third routine for communicating the treatment instruction to the output means;

    (e) receiving from the computing device the treatment instruction; and

    (f) administering a next FK 506 dose to the patient in accordance with the treatment instruction.

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