Collection and display device

• US 5,366,902 A
• Filed: 06/22/1993
• Issued: 11/22/1994
• Est. Priority Date: 10/30/1990
• Status: Expired due to Fees

• Current Assignee: Hypoguard USA Inc.
• Original Assignee: Hypoguard USA Inc.
• Inventors: Cox, Stephen J., Lydford, Thomas
• Primary Examiner(s): BHAT, NINA NMN
• Application Number:
  US08/050,168
• Time in Patent Office: 518 Days
• Field of Search: 422/56, 422/57, 422/58, 422/100, 422/101, 422/102, 436/165, 436/169, 436/180, 436/178
• US Class Current: 436/165
• CPC Class Codes: B01L 2200/0684 Venting, avoiding backpressure, avoid gas bubbles
• CPC Class Codes: B01L 2300/0832 cylindrical, tube shaped
• CPC Class Codes: B01L 2400/0406 capillary forces
• CPC Class Codes: B01L 3/502723 characterised by venting arrangements
• CPC Class Codes: Y10T 436/255 including use of a solid sorbent, semipermeable membrane, or liquid extraction
• CPC Class Codes: Y10T 436/2575 Volumetric liquid transfer

Abstract

A device and method are shown for assessing a fluid sample. The device includes a fluid receptor for receiving a sample of a fluid from an external source and a closed chamber for receiving fluid from the receptor through a fluid flow connection. Part of a wall of the chamber is provided by a member which carries a reagent which responds to a component of the fluid sample, whereby an indication of the response can be detected from the exterior of the chamber.

Claims

1. A device for assessing a fluid sample, which device comprises:

a. a fluid receptor means for receiving a sample of a fluid from an external source, said fluid receptor means comprising a cup or recess having an exposed open top having a rim across which a user may wipe his finger so as to transfer a sample of blood from the finger into the cup or recess;

b. a substantially closed chamber adapted to receive fluid from the receptor means;

c. a bore connecting the fluid receptor means and the chamber for transferring said fluid from the receptor means to the chamber, which bore has an outlet at said chamber end of the bore;

d. a generally planar member removably mounted upon the device and providing at least part of one wall of said chamber, said member carrying one or more reagents adapted to respond to one or more components of the fluid sample and adapted to give an indication of that response which can be detected from the exterior of the chamber, said reagents being located generally centrally on said member and in register with the outlet of said bore into the chamber;

wherein the diameter of the outlet of said device is selected such that the fluid in the bore is adapted to form a droplet or meniscus at the outlet to the bore, whereby the bore is adapted to conduct the fluid from the receptor to the chamber and to deposit the fluid substantially centrally onto the reagent carrying area of the said reagent carrying member.

2. A device as claimed in claim 1, wherein the said reagent is located on or accessible from the chamber adjacent face of the said generally planar member and is adapted to provide a visual display of the response from the reagent to the sample at the other face thereof.

3. A device as claimed in claim 1, wherein the chamber is provided with means to vent or accommodate air displaced by the fluid entering the chamber.

4. A device as claimed in claim 1, wherein the chamber and the fluid receptor are connected by a capillary bore.

5. A device as claimed in claim 1, wherein it is of a generally radially symmetrical form having the fluid receptor located at one end thereof and the chamber at the other end thereof and having an axial bore for fluid flow connection between the chamber and the receptor.

6. A device as claimed in claim 1, wherein the generally planar member forms at least part of the transverse end wall of the chamber.

7. A device as claimed in claim 6, wherein the generally planar member comprises a transparent or translucent planar member having applied thereto and accessible from one face thereof the reagents to respond to the fluid sample and adapted to provide a visual response to the fluid sample through the other face of the member.

8. A device as claimed in claim 1, wherein the chamber has an internal transverse diameter to axial depth ratio which is from 12:

1 to 5;

1.

9. A device as claimed in claim 1, wherein the bore has a diameter of from 0.25 to 2.5 mms and the chamber has an axial depth of from 0.5 to5 mms.

10. A device as claimed in claim 1, wherein the reagent(s) respond to glucose in a blood sample.

11. A device as claimed in claim 1, wherein the said generally planar member comprises a transparent or translucent substrate adapted to be removably attached across an open end face of the chamber, the substrate carrying one or more test reagents applied thereto and carrying an annular disc of an opaque material surrounding the reagents so as to restrict the development of the response to the fluid sample to the central area of the substrate.

12. A method for testing a fluid sample for the presence of a component or property therein, wherein the sample of fluid is applied to the fluid receptor of a device as claimed in claim 1, the fluid is allowed to flow through the bore to the chamber and to form a drop or partial drop at the chamber end of the bore which contacts the reagent carrying surface of the generally planar member so as to contact the reagent(s) carried thereon;

and observing the response of the reagent(s) to the fluid externally through the planar member.

13. A method as claimed in claim 12, wherein the fluid is blood and the reagents give a colour response to the glucose content of the sample.